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Cruises From Santa Cruz de Tenerife

Choose from 57 unique cruises starting in Santa Cruz de Tenerife, and travelling to Barcelona, Bari, Lisbon, Madeira, Miami and more. December is the most popular month to join a cruise from Santa Cruz de Tenerife and you can select from 195 departures available from four leading cruise lines.
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21 Days
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57 Cruises (195 Cruise Departures)
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,029
OCEANVIEW
$1,247
BALCONY
$1,920
SUITE
$2,840
From 1,029
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 28 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,703
OCEANVIEW
$2,039
BALCONY
$2,404
SUITE
-
From 1,703
View Trip
12 Day Canary Islands And Madeira with MSC Cruises
Cruise

12 Days (11 Nights) Santa Cruz de Tenerife to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+2 more), Italy, Croatia
Save And Sail Offer
INSIDE
$1,567
OCEANVIEW
$1,914
BALCONY
$2,844
SUITE
$4,280
From 1,567
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$693
OCEANVIEW
$1,049
BALCONY
$1,315
SUITE
$2,157
From 693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
INSIDE
$3,643
OCEANVIEW
$4,104
BALCONY
$5,132
SUITE
-
From 3,643
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
INSIDE
$1,772
OCEANVIEW
$1,959
BALCONY
$2,621
SUITE
$4,353
From 1,772
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 20 December 2025
Countries Visited: Spain, Portugal
INSIDE
$3,643
OCEANVIEW
$4,104
BALCONY
$5,132
SUITE
-
From 3,643
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 24 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,029
OCEANVIEW
$1,247
BALCONY
$1,920
SUITE
$2,840
From 1,029
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 13 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
INSIDE
$2,655
OCEANVIEW
$3,402
BALCONY
$4,084
SUITE
-
From 2,655
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
-
From 1,633
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$712
OCEANVIEW
$969
BALCONY
$1,315
SUITE
$2,087
From 712
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$4,016
SUITE
$5,213
From 1,748
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Feb 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,471
SUITE
$4,332
From 1,497
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
INSIDE
$1,653
OCEANVIEW
$1,959
BALCONY
$2,621
SUITE
$3,927
From 1,653
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 22 December 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,603
OCEANVIEW
$1,821
BALCONY
$2,494
SUITE
$3,415
From 1,603
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 28 December 2024
Countries Visited: Spain, Portugal
INSIDE
$3,081
OCEANVIEW
$3,750
BALCONY
$4,451
SUITE
-
From 3,081
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$2,055
BALCONY
$2,657
SUITE
$4,744
From 1,633
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 01 November 2025
Countries Visited: Spain, Portugal
INSIDE
$2,059
OCEANVIEW
$2,451
BALCONY
$3,301
SUITE
$5,368
From 2,059
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$693
OCEANVIEW
$969
BALCONY
$1,345
SUITE
$2,157
From 693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$1,762
OCEANVIEW
$1,976
BALCONY
$2,657
SUITE
$4,744
From 1,762
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 14 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
INSIDE
$2,525
OCEANVIEW
$3,154
BALCONY
$3,756
SUITE
-
From 2,525
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2024
Countries Visited: Spain, Portugal
INSIDE
$2,883
OCEANVIEW
$3,899
BALCONY
$4,451
SUITE
$9,945
From 2,883
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco, Corsica, Sardinia (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$19,246
BALCONY
-
SUITE
$26,918
Save 6,694
From 19,246
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$763
OCEANVIEW
$1,079
BALCONY
$1,315
SUITE
$2,206
From 763
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 14 December 2024
Countries Visited: Spain, Portugal
INSIDE
$3,309
OCEANVIEW
$3,978
BALCONY
$4,778
SUITE
-
From 3,309
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$712
OCEANVIEW
$969
BALCONY
$1,413
SUITE
$2,095
From 712
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2024 to Feb 2025
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$959
OCEANVIEW
$1,177
BALCONY
$1,850
SUITE
$2,771
From 959
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
INSIDE
$3,366
OCEANVIEW
$3,906
BALCONY
$4,885
SUITE
-
From 3,366
View Trip
11 Day Canary Islands & Spanish coast with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Santa Cruz de Tenerife to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,242
BALCONY
-
SUITE
$14,202
Save 2,603
From 10,242
View Trip
13 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

13 Days (12 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,515
OCEANVIEW
$1,839
BALCONY
$2,599
SUITE
-
From 1,515
View Trip
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