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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 451 unique cruise itineraries from 10 leading cruise lines. September is the most popular month to join a luxury cruise in the Mediterranean with 542 departures starting between May 2024 and April 2027.
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451 Cruises (542 Cruise Departures)
19 Day Andalusian Nights & Monte Carlo Masters with Seabourn
Cruise

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Seabourn
Ship: Venture
Departure: 26 March 2025
Countries Visited: Portugal, Spain, Morocco, France (+2 more), Monaco, Italy
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$17,946
SUITE
$43,443
From 17,946
View Trip
12 Day Antiquity To Anatolia with Oceania Cruises
Cruise

12 Days (11 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,924
SUITE
$10,844
Save 2,056
From 6,924
View Trip
13 Day Tyrrhenian Treasures & Malta with Seabourn
Cruise

13 Days (12 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 September 2024
Countries Visited: Monaco, Italy, Sicily, Malta (+3 more), Corsica, France, Spain
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$12,187
SUITE
$22,087
From 12,187
View Trip
15 Day Ultimate Treasures of Spain & the Mediterranean with Scenic
New ReleaseCruise

15 Days (14 Nights) Malaga to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 22 April 2025
Countries Visited: Spain, Gibraltar, France, Monaco
Earlybird SavingExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,695
SUITE
$28,235
Save 7,635
From 17,695
View Trip
22 Day Cradle Of Empires with Oceania Cruises
Cruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 30 October 2024
Countries Visited: Italy, France, Malta, Sicily (+3 more), Croatia, Montenegro, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,597
SUITE
$18,596
Save 2,103
From 12,597
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,579
BALCONY
-
SUITE
$8,890
Save 1,566
From 6,579
View Trip
10 Day Exquisite Mediterranean with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 05 September 2024
Countries Visited: Italy, Sicily, Greece, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,315
SUITE
$14,790
Save 4,225
From 13,315
View Trip
8 Day Cruising the Mediterranean: Sicily, Sardinia, and Mallorca - with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Valletta to Tarragona
Cruise Line: Ponant
Ship: L'Austral
Departure: 03 October 2025
Countries Visited: Malta, Sicily, Sardinia, Spain
Exclusive Savings
INSIDE
-
OCEANVIEW
$6,772
BALCONY
$7,282
SUITE
$10,859
Save 128
From 6,772
View Trip
11 Day Ramparts & Rivieras with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 August 2025
Countries Visited: Italy, Sicily, Malta, Spain (+2 more), France, Monaco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,953
SUITE
$11,705
Save 2,067
From 7,953
View Trip
9 Day Rome to Rome with Silversea
Cruise

9 Days (8 Nights) Rome to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Tunisia, France
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,078
From 12,078
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Aug 2024 to Sep 2024
Countries Visited: Spain, Sardinia, Corsica, Sicily (+1 more), Italy
INSIDE
$2,130
OCEANVIEW
$2,328
BALCONY
$2,932
SUITE
$4,120
From 2,130
View Trip
8 Day Iconic Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 09 June 2025
Countries Visited: Greece, Italy, Monaco, France (+1 more), Spain
Exclusive Deal
INSIDE
$4,190
OCEANVIEW
$4,952
BALCONY
$5,715
SUITE
$7,457
Save 2,030
From 4,190
View Trip
13 Day Mediterranean Melody with Oceania Cruises
Cruise

13 Days (12 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 September 2025
Countries Visited: Spain, France, Monaco, Italy (+3 more), Sicily, Greece, Turkey
Exclusive Deal
INSIDE
$6,926
OCEANVIEW
-
BALCONY
$9,371
SUITE
$12,539
Save 2,054
From 6,926
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 08 October 2026
Countries Visited: Portugal, Spain, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,182
BALCONY
-
SUITE
$15,142
Save 2,613
From 11,182
View Trip
11 Day Mediterranean Overture with Seabourn
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 30 October 2024
Countries Visited: Italy, Sardinia, Corsica, Monaco (+2 more), France, Spain
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,315
SUITE
$16,146
From 9,315
View Trip
31 Day Malta, Morocco & Mediterranean with Seabourn
Cruise

31 Days (30 Nights) Rome to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 21 June 2025
Countries Visited: Italy, Malta, Tunisia, France (+4 more), Spain, Gibraltar, Morocco, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$23,841
SUITE
$43,028
From 23,841
View Trip
12 Day Barcelona to Lisbon with Silversea
Cruise

12 Days (11 Nights) Barcelona to Lisbon
Cruise Line: Silversea
Ship: Silver Ray
Departure: 23 November 2024
Countries Visited: Gibraltar, Morocco, Portugal, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,286
From 11,286
View Trip
11 Day Nice to Barcelona with Silversea
Cruise

11 Days (10 Nights) Nice to Barcelona
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 27 July 2025
Countries Visited: France, Corsica, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,286
BALCONY
$12,078
SUITE
$19,701
From 11,286
View Trip
10 Day Athens to Athens with Silversea
Cruise

10 Days (9 Nights) Athens to Athens
Cruise Line: Silversea
Ship: Silver Muse
Departure: 08 October 2025
Countries Visited: Greece, Turkey, Cyprus, Israel
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$10,296
SUITE
$15,840
From 10,296
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save 2,098
From 9,747
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 11 August 2025
Countries Visited: Italy, France, Corsica, Spain
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
8 Day Mediterranean Tapestry with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 15 November 2024
Countries Visited: Italy, France, Spain
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$3,830
BALCONY
$5,006
SUITE
$5,927
Save 7,440
From 3,830
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sicily
INSIDE
$2,726
OCEANVIEW
$2,974
BALCONY
$3,370
SUITE
$7,231
From 2,726
View Trip
8 Day Exploring the Balearic Islands with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: Oct 2025 to Oct 2025
Countries Visited: Spain, France
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,678
BALCONY
-
SUITE
$8,989
Save 1,567
From 6,678
View Trip
11 Day Tyrrhenian Treasures & Malta with Seabourn
Cruise

11 Days (10 Nights) Monte Carlo to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: Apr 2025 to Sep 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+3 more), Corsica, France, Spain
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$8,929
SUITE
$15,913
From 8,929
View Trip
8 Day Monte Carlo to Rome with Silversea
Cruise

8 Days (7 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 July 2025
Countries Visited: Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,801
From 9,801
View Trip
8 Day A Journey From Barcelona To Rome with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 13 May 2025
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$6,192
SUITE
$7,529
From 6,192
View Trip
8 Day Barcelona to Lisbon with Silversea
Cruise

8 Days (7 Nights) Barcelona to Lisbon
Cruise Line: Silversea
Ship: Silver Moon
Departure: 11 October 2024
Countries Visited: Morocco, Portugal, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$12,375
SUITE
$14,256
From 12,375
View Trip
8 Day Etruscan Waterways with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 21 April 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
$3,872
OCEANVIEW
$4,714
BALCONY
$5,248
SUITE
$7,298
Save 2,028
From 3,872
View Trip
11 Day Mediterranean Wanderlust with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 September 2025
Countries Visited: Spain, France, Italy, Malta (+1 more), Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,465
SUITE
$15,010
Save 6,175
From 13,465
View Trip
Results: 61-90 of 451

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