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Cruises from Fort Lauderdale to San Diego

Are you looking for a cruise from Fort Lauderdale to San Diego? April is the most popular month to cruise between Fort Lauderdale and San Diego and there are 7 departures available from two of the world's leading cruise lines.
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7 Cruises (7 Cruise Departures)
30 Day Panama Canal & Eastern Caribbean with Holland America
Cruise
 (2)

30 Days (29 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 29 March 2026
Visit: USA, Puerto Rico, Virgin Islands, Antigua and Barbuda (+10 more), Dominica, Saint Lucia, Saint Kitts and Nevis, Bahamas, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$3,509
Oceanview
$4,411
Balcony
$5,753
Suite
-
From
US$3,509
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$2,344
Oceanview
$2,754
Balcony
$3,795
Suite
$5,942
From
US$2,344
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (2)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 10 April 2026
Visit: USA, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$2,199
Oceanview
$2,709
Balcony
$3,549
Suite
-
From
US$2,199
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 March 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$2,299
Oceanview
$2,599
Balcony
$4,233
Suite
$8,349
From
US$2,299
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 05 April 2026
Visit: USA, Colombia, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$2,214
Oceanview
-
Balcony
$3,404
Suite
$7,374
From
US$2,214
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (3)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$2,614
Oceanview
$3,024
Balcony
$4,063
Suite
$6,503
From
US$2,614
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Princess
Ship: Island Princess
Departure: 13 January 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$2,089
Oceanview
$2,169
Balcony
$3,139
Suite
$3,882
From
US$2,089
Per Person
View Trip
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