Best of South America with Amazon Cruise

Welcome to Santiago. We'll meet you on arrival and transfer you to your hotel. Then, set off on a guided discovery of Chile's capital, wedged between the snow-capped Andes mountains and the Pacific Ocean.

Tonight, join a welcome reception. Stay Two Nights: The Singular Santiago

• Explore this World Heritage-listed city's historic quarter before a funicular ride offering great views over Valparaiso.

• In Buenos Aires, enjoy a taste of local culture with a tango demonstration and a selection of tapas.

Join a guided discovery of the city, which includes the Italian-influenced barrio of La Boca, a neighbourhood known for its Latino vibe and brightly painted pedestrian streets. Explore the bohemian district of Palermo, filled with trendy eateries and galleries, before arriving at La Recoleta Cemetery. This is the resting place of Argentine notables such as the nation's former First Lady Eva Peron. (B)

• Perhaps journey to the island of Tigre for a cruise along the waterways of the Parana Delta. Discover daily life within this maze of rainforest and tiny islands, which is also a haven for birdlife. Or you might like to explore the Parisian influence on Buenos Aires during a walking tour. Alternatively, join a fascinating tour of the iconic and majestic Teatro Colon, considered the world's leading opera house by acoustic finesse, and immerse yourself in the city's sophisticated high arts scene.
• Tonight, choose from three dining options: dinner and a tango show; dine in style at Alvear Grill; or sit down to a traditional Argentinian Asado experience.

• Stay within Brazil's Iguazu National Park for two nights, enjoying the property's unrivalled location.

• Get up close to the roaring cascades of Iguazu Falls on an included jet boat safari, or for a special bird's-eye-view, soar over the falls on a helicopter flight.

• Indulge in a cachaca tasting this evening at your hotel, which boasts one of the largest cachaca collections in Brazil. In celebration of Brazil's national spirit, well known as the key ingredient in the Caipirinha cocktail, a cachaca sommelier will lead you on a delightful journey of flavours.

Begin your day with a visit to Parque das Aves bird sanctuary where you'll see a spectacular array of colourful native South American birds.

Later, fly to Rio de Janeiro, Brazil's most visited and naturally blessed city, set between lush forest mountains and sandy shores.

On arrival, we'll meet and transfer you to the elegant art deco grandeur of your hotel opposite the golden sands of iconic Copacabana Beach. Stay Three Nights: Rio de Janeiro, Belmond Copacabana Palace (B)

See Rio from above with a visit to Corcovado, the mountain famed for its Christ the Redeemer statue, the world's largest art deco sculpture. From here, enjoy sweeping city views. Towards evening, board a cable car to the summit of Sugarloaf Mountain to toast the sunset and incredible views with a drink.

Tonight, dine at a local restaurant for Brazil's famously delicious barbecue fare. (B/D)

• This morning is set aside for you to sail the waters of Guanabara Bay aboard a schooner sailing ship. If you'd prefer to stay on dry land, perhaps join a colonial walking tour, where the legends woven through the city's narrow colonial-era streets are brought to life.

Enjoy a leisurely morning before lunch at Confeitaria Colombo, an ornate coffee house considered one of the most beautiful cafes in the world and an iconic landmark of downtown Rio.

Afterwards, we'll transfer you to the airport for your included flight to Lima. In Lima, we'll meet and transfer you to your hotel. Stay Two Nights: Country Club Lima Hotel (B/L)

• Pay a visit to a private hacienda to enjoy lunch and a Peruvian Paso horse show.

• Enjoy a traditional weaving demonstration which reveals how South America's colourful materials are created by hand.

• See the glistening salt pools spill over the terraced slopes at the World Heritage-listed Salt Mines of Maras. Visit the circular Moray Inca terraces archaeological site.

• Board Inca Rail's First Class Train and travel through forested landscapes to the lost Inca citadel of Machu Picchu. Enjoy a gourmet Andean-inspired lunch on board while taking in the view.

This morning, relax at your hotel and perhaps join a culinary demonstration to learn the secrets of South American cuisine. Board the 360° train for your return trip to the Sacred Valley. Here, transfer by coach to Cusco and settle into your hotel in the heart of this historic city. Stay Two Nights: Cusco, Palacio del Inka, a Luxury Collection Hotel (B)

A guided discovery of Cusco takes you to Plaza de Armas, a square at the city's historic heart. You'll also visit the sacred sites of Koricancha and Cusco Cathedral.

This evening, dine on flavours of Peru at MAP Cafe, located in the central courtyard of the Museum of Pre-Columbian Art. (B/D)

Board an early flight via Lima to Iquitos, a city located on the banks of the Peruvian Amazon. Here, you'll step aboard your boutique vessel and set off to discover the spectacular flora and fauna as you explore the Pacaya-Samiria National Reserve. Naturalist guides will reveal the secrets of the rainforest and its inhabitants; taking skiff boats to hidden corners of the river, trail walks through the lush vegetation, or on a gentle kayak in calm creeks.

This afternoon, embark on a skiff exploration along the Maranon River and listen to the rhythmic sounds of the jungle as you settle in. Stay Four Nights: Delfin III (B/D)

Spend the morning on the waters of the Samiria River on a skiff exploration. Travel on a stable and safe boat accompanied by an expert naturalist guide and learn about this part of the river. After lunch, relax back on board before you ascend to the canopy on a suspended walkway, one of the longest treetop walks in the world, to get a higher perspective of the rainforest. Encounter the birds and animals less visible from below on this spectacular excursion. (B/L/D)

Get even closer to the water on a kayaking trip in the calm waters of the Reserve at Yanayacu Pucate Then, search for more amazing creatures and vegetation, as your naturalist guide takes you deep into the rainforest on a jungle walk at Fundo Casual. Get an intimate view of the Amazon's ecosystem and wildlife inhabiting this unique environment including frogs, snakes and insects. (B/L/D)

Today you have the chance to fish for piranhas on the Yarapa River and discover other exotic animals who call the river home. As you cruise, watch for scarlet macaws, Amazonian parrotlets, iguanas and squirrel monkeys. (B/L/D)

Your cruise ends with a transfer to Iquitos. On the way, stop off for a visit to the Rescue and Rehabilitation Center of River Mammals. Learn about the rescue work achieved by volunteers at the centre, then hear about manatees and feed these majestic, endangered animals. (B)