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Cruises Starting and Ending in Colon

Are you looking for a cruise starting and ending in Colon? December is the most popular month to join a roundtrip cruise from Colon and we have 25 departures available from one of the world's leading cruise lines.
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9 Days
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$2,790pp
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11 Cruises (25 Cruise Departures)
9 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

9 Days (8 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 12 December 2025
Countries Visited: Panama, Colombia, Bonaire, Aruba (+1 more), Curacao
Exclusive Deal
INSIDE
$1,723
OCEANVIEW
$1,784
BALCONY
$2,032
SUITE
$2,753
Save (per person) 411
From (per person) 2,037
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 17 January 2026
Countries Visited: Panama, Colombia, Bonaire, Aruba
Exclusive Deal
INSIDE
$1,606
OCEANVIEW
$1,618
BALCONY
$1,738
SUITE
$2,713
Save (per person) 386
From (per person) 1,899
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2026 to Feb 2026
Countries Visited: Panama, Colombia, Bonaire, Aruba
Exclusive Deal
INSIDE
$1,298
OCEANVIEW
$1,412
BALCONY
$1,731
SUITE
$2,741
Save (per person) 344
From (per person) 1,530
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Jan 2026 to Mar 2026
Countries Visited: Panama, Colombia, Aruba, Curacao
Exclusive Deal
INSIDE
$1,423
OCEANVIEW
$1,574
BALCONY
$1,909
SUITE
$2,777
Save (per person) 373
From (per person) 1,679
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2025 to Nov 2025
Countries Visited: Panama, Colombia, Bonaire, Curacao
Exclusive Deal
INSIDE
$1,441
OCEANVIEW
$1,510
BALCONY
$1,809
SUITE
$2,468
Save (per person) 353
From (per person) 1,703
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 20 December 2025
Countries Visited: Panama, Colombia, Curacao, Aruba
Exclusive Deal
INSIDE
$1,704
OCEANVIEW
$1,810
BALCONY
$2,097
SUITE
$3,117
Save (per person) 414
From (per person) 2,019
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2025 to Apr 2026
Countries Visited: Panama, Colombia, Curacao, Aruba
Exclusive Deal
INSIDE
$1,422
OCEANVIEW
$1,555
BALCONY
$1,722
SUITE
$2,395
Save (per person) 371
From (per person) 1,678
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2025 to Feb 2026
Countries Visited: Panama, Colombia, Aruba, Bonaire
Exclusive Deal
INSIDE
$1,369
OCEANVIEW
$1,445
BALCONY
$1,704
SUITE
$2,665
Save (per person) 479
From (per person) 1,614
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2025 to Nov 2025
Countries Visited: Panama, Colombia, Aruba, Curacao
Exclusive Deal
INSIDE
$1,444
OCEANVIEW
$1,527
BALCONY
$1,745
SUITE
$2,395
Save (per person) 400
From (per person) 1,706
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

7 Days (6 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 06 December 2025
Countries Visited: Panama, Colombia, Aruba, Curacao
Exclusive Deal
INSIDE
$1,427
OCEANVIEW
$1,543
BALCONY
$1,789
SUITE
$2,672
Save (per person) 340
From (per person) 1,684
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2025 to Apr 2026
Countries Visited: Panama, Colombia, Aruba, Curacao
Exclusive Deal
INSIDE
$1,422
OCEANVIEW
$1,496
BALCONY
$1,776
SUITE
$2,689
Save (per person) 398
From (per person) 1,678
View Trip
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