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USA Cruises Starting In September 2025

If you're looking at joining a cruise up and down the east and west coasts of the US in September 2025, we have 19 unique cruises with 131 departures from the world's leading cruise lines departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
4 Days
21 Days
Regions
Start & End Cities
Ship Size
Ship Features
Cruise Lines
Price
$100pp
$48,180pp
Countries
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19 Cruises (131 Cruise Departures)
8 Day Great Lakes Explorer with Viking Cruises
Cruise

8 Days (7 Nights) Milwaukee to Thunder Bay
Operated By: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Jun 2025 to Sep 2025
Countries Visited: USA, Canada
INSIDE
-
OCEANVIEW
-
BALCONY
$7,695
SUITE
$10,495
From (per person) 7,695
View Trip
8 Day Pacific Wine Country with Princess
Cruise

8 Days (7 Nights) Vancouver to Los Angeles
Cruise Line: Princess
Ships: Caribbean Princess, Island Princess
Departures: Sep 2025 to Sep 2026
Countries Visited: Canada, USA
Exclusive Deal
INSIDE
$609
OCEANVIEW
$682
BALCONY
$849
SUITE
$1,119
From (per person) 609
View Trip
6 Day Pacific Coastal Cruise with Holland America
Cruise

6 Days (5 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 24 September 2025
Countries Visited: Canada, USA
Exclusive Deal
INSIDE
$724
OCEANVIEW
$724
BALCONY
$1,294
SUITE
$2,574
From (per person) 724
View Trip
8 Day A Voyage Along the Great Lakes – with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Toronto to Milwaukee
Cruise Line: Ponant
Ship: Le Champlain
Departure: 17 September 2025
Countries Visited: Canada, USA
INSIDE
-
OCEANVIEW
-
BALCONY
$12,260
SUITE
$17,890
From (per person) 12,260
View Trip
12 Day Classic California Coast with Princess
Cruise
 (2)

12 Days (11 Nights) Vancouver to Vancouver
Cruise Line: Princess
Ship: Coral Princess
Departure: 24 September 2025
Countries Visited: Canada, USA
Exclusive Deal
INSIDE
$1,978
OCEANVIEW
$2,028
BALCONY
$2,214
SUITE
$2,878
From (per person) 1,978
View Trip
8 Day Niagara & the Great Lakes with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Milwaukee to Toronto
Operated By: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: May 2025 to Sep 2027
Countries Visited: USA, Canada
INSIDE
-
OCEANVIEW
-
BALCONY
$6,295
SUITE
$9,195
From (per person) 6,295
View Trip
7 Day Pacific Coastal Cruise with Holland America
Cruise
 (1)

7 Days (6 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 28 September 2025
Countries Visited: Canada, USA
Exclusive Deal
INSIDE
$739
OCEANVIEW
$1,039
BALCONY
$1,039
SUITE
$1,939
From (per person) 739
View Trip
6 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

6 Days (5 Nights) Vancouver to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 14 September 2025
Countries Visited: Canada, USA
Exclusive DealExclusive Solo Offer
INSIDE
$449
OCEANVIEW
$498
BALCONY
$618
SUITE
$2,266
Save (per person) 156
From (per person) 449
View Trip
8 Day Pacific Wine Country with Princess
Cruise
 (10)

8 Days (7 Nights) Vancouver to Los Angeles
Cruise Line: Princess
Ship: Royal Princess
Departure: 27 September 2025
Countries Visited: Canada, USA
Exclusive Deal
INSIDE
$629
OCEANVIEW
-
BALCONY
$774
SUITE
$1,079
From (per person) 629
View Trip
9 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

9 Days (8 Nights) Vancouver to San Diego
Cruise Line: Royal Caribbean
Ship: Radiance of the Seas
Departure: 26 September 2025
Countries Visited: Canada, USA
Exclusive DealExclusive Solo Offer
INSIDE
$717
OCEANVIEW
$797
BALCONY
$1,073
SUITE
-
Save (per person) 305
From (per person) 717
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Los Angeles to Los Angeles
Cruise Line: Royal Caribbean
Ships: Navigator of the Seas, Ovation of the Seas, Quantum of the Seas
Departures: Mar 2025 to Apr 2027
Countries Visited: USA, Mexico
Mutiple Deals Available
INSIDE
$285
OCEANVIEW
$305
BALCONY
$304
SUITE
$502
Save (per person) 1,003
From (per person) 285
View Trip
12 Day Cruising the Great Lakes: Toronto to Chicago with Tauck
Cruise

12 Days (11 Nights) Toronto to Chicago
Operated By: Tauck
Departure: 01 September 2025
Countries Visited: Canada, USA
Complimentary Hotel Night
From (per person) 10,790
View Trip
12 Day Inside Passage with Glacier Bay National Park with Princess
Cruise

12 Days (11 Nights) San Francisco to San Francisco
Cruise Line: Princess
Ship: Ruby Princess
Departures: May 2025 to Sep 2025
Countries Visited: USA, Canada
Exclusive Deal
INSIDE
$1,299
OCEANVIEW
$1,517
BALCONY
$2,099
SUITE
$2,884
From (per person) 1,299
View Trip
14 Day Mexican Riviera & Pacific Coast with Holland America
Cruise
 (1)

14 Days (13 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 28 September 2025
Countries Visited: Canada, USA, Mexico
Exclusive Deal
INSIDE
$1,349
OCEANVIEW
$1,849
BALCONY
$1,849
SUITE
$3,249
From (per person) 1,349
View Trip
21 Day Mexican Riviera, California And Pacific Coast with Holland America
Cruise
 (1)

21 Days (20 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 28 September 2025
Countries Visited: Canada, USA, Mexico
Exclusive Deal
INSIDE
$1,938
OCEANVIEW
$2,618
BALCONY
$2,618
SUITE
$4,913
From (per person) 1,938
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Los Angeles to Los Angeles
Cruise Line: Royal Caribbean
Ships: Navigator of the Seas, Ovation of the Seas (+2 more), Quantum of the Seas, Voyager of the Seas
Departures: Jun 2025 to Mar 2027
Countries Visited: USA, Mexico
Exclusive DealExclusive Solo Offer
INSIDE
$305
OCEANVIEW
$302
BALCONY
$345
SUITE
$510
Save (per person) 269
From (per person) 302
View Trip
15 Day Canada & East Coast Explorer with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Toronto to Fort Lauderdale
Operated By: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2025 to Oct 2026
Countries Visited: Canada, USA
INSIDE
-
OCEANVIEW
-
BALCONY
$9,995
SUITE
$14,995
From (per person) 9,995
View Trip
13 Day Eastern Seaboard Explorer with Viking Cruises
Cruise
 (7)

13 Days (12 Nights) New York to Montreal
Operated By: Viking Cruises
Ship: Viking Mars
Departures: Sep 2025 to Oct 2027
Countries Visited: USA, Canada
INSIDE
-
OCEANVIEW
-
BALCONY
$6,499
SUITE
$11,749
From (per person) 6,499
View Trip
13 Day Eastern Seaboard Explorer with Viking Cruises
Cruise

13 Days (12 Nights) Montreal to New York
Operated By: Viking Cruises
Ships: Viking Mars, Viking Neptune
Departures: May 2025 to Sep 2027
Countries Visited: Canada, USA
INSIDE
-
OCEANVIEW
-
BALCONY
$6,499
SUITE
$10,749
From (per person) 6,499
View Trip
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