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River Cruises from Amsterdam to Prague

Are you looking for a river cruise from Amsterdam to Prague? November is the most popular month to river cruise between Amsterdam and Prague and there are 47 departures available from two of the world's leading river cruise lines.
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$5,200pp
$28,175pp
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5 River Cruises (47 River Cruise Departures)
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$9,194
Balcony
$12,007
Suite
$15,596
From
US$9,194
Save 9,014
Per Person
View Trip
18 Day Prague & Christmas Markets of Europe with Emerald Cruises
River Cruise
 (5)

18 Days Amsterdam to Prague
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Fly Free Economy
Exclusive Savings
Inside
-
River View
$6,725
Balcony
$8,762
Suite
$13,214
From
US$6,725
Save 7,225
Per Person
View Trip
18 Day Splendours of Europe & Prague with Emerald Cruises
River Cruise
 (2)

18 Days Amsterdam to Prague
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$5,294
Balcony
$7,331
Suite
$11,793
From
US$5,294
Save 10,061
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Holland, Germany, Austria, Hungary, Czech Republic
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$8,951
Balcony
$11,910
Suite
$16,323
From
US$8,951
Save 8,763
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Aug 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Multiple Deals Available
Inside
-
River View
$7,967
Balcony
$10,925
Suite
$13,947
From
US$7,967
Save 14,059
Per Person
View Trip
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River Cruises from Amsterdam

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