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River Cruises from Amsterdam to Prague

Are you looking for a river cruise from Amsterdam to Prague? December is the most popular month to river cruise between Amsterdam and Prague and there are 91 departures available from four of the world's leading river cruise lines.
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8 River Cruises (91 River Cruise Departures)
18 Day European Gems - Amsterdam to Prague with Travelmarvel
River Cruise
 (7)

18 Days Amsterdam to Prague
Operated By: Travelmarvel
Ships: Capella, Polaris (+2 more), Rigel, Vega
Departures: May 2025 to Dec 2026
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Hungary (+1 more), Czech Republic
Exclusive Deal
Save (per person) 3,359
From (per person) 6,396
View Trip
18 Day Magnificent Europe with Prague with APT
River Cruise
 (11)

18 Days Amsterdam to Prague
Operated By: APT
Ships: APT Ostara, APT Solara
Departures: Jun 2025 to Dec 2026
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Flights IncludedFlights Included + Save
Save (per person) 838
From (per person) 11,198
View Trip
18 Day Prague & Christmas Markets of Europe with Emerald Cruises
River Cruise
 (2)

18 Days Amsterdam to Prague
Operated By: Emerald Cruises
Ships: Emerald Sun, Emerald Dawn
Departures: Dec 2025 to Nov 2026
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$7,431
BALCONY
$9,114
SUITE
$11,995
Save (per person) 2,567
From (per person) 7,431
View Trip
18 Day Splendours of Europe & Prague with Emerald Cruises
River Cruise
 (2)

18 Days Amsterdam to Prague
Operated By: Emerald Cruises
Ships: Emerald Luna, Emerald Sun (+5 more), Emerald Astra, Emerald Dawn, Emerald Destiny, Emerald Sky, Emerald Star
Departures: Jun 2025 to Oct 2026
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$7,233
BALCONY
$9,510
SUITE
$12,143
Save (per person) 3,565
From (per person) 7,233
View Trip
24 Day Eastern Europe and European Gems River Cruise with Travelmarvel
River Cruise

24 Days Amsterdam to Prague
Operated By: Travelmarvel
Ships: Polaris, Vega
Departure: 26 May 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Hungary (+3 more), Slovakia, Poland, Czech Republic
Exclusive Deal
Save (per person) 1,912
From (per person) 12,783
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Operated By: Scenic
Ships: Scenic Crystal, Scenic Jade (+4 more), Scenic Jewel, Scenic Amber, Scenic Jasper, Scenic Opal
Departures: Jul 2025 to Oct 2026
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Hungary (+2 more), Slovakia, Czech Republic
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$9,114
BALCONY
$13,425
SUITE
$17,014
Save (per person) 2,603
From (per person) 9,114
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Operated By: Scenic
Ships: Scenic Jade, Scenic Opal
Departures: Nov 2025 to Nov 2026
Rivers: Danube, Main, Rhine
Countries Visited: Holland, Germany, Austria, Hungary (+1 more), Czech Republic
Super Earlybird
INSIDE
-
RIVER VIEW
$9,362
BALCONY
$13,524
SUITE
$17,846
Save (per person) 2,583
From (per person) 9,362
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Operated By: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2025 to Dec 2026
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Super Earlybird
INSIDE
-
RIVER VIEW
$9,956
BALCONY
$14,118
SUITE
$17,707
Save (per person) 2,589
From (per person) 9,956
View Trip
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River Cruises from Amsterdam to Prague

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