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Home > Operators > HX Expeditions > Ships > MS Santa Cruz II
HX Expeditions

MS Santa Cruz II

MS Santa Cruz II offers guests an exceptional cruising experience, with a cozy guest capacity of a maximum of 90, it creates a relaxed yet classy atmosphere. This environmentally-conscious ship operates carbon-neutrally with a sleek and spacious layout which provides ample opportunities to enjoy your cruise. From savoring mouthwatering meals in the elegant restaurant to engaging with fellow travelers in the Science Center, MS Santa Cruz II truly feels like a home away from home for world explorers.
173
Cruises On Sale
Ship Type
Expedition Cruise Ship
Passengers
90
Crew
50
Launched
2002
Refurbished
2021

MS Santa Cruz II Cruises View all Choose from 173 vacations cruising on board the MS Santa Cruz II

Galápagos Islands - Nine Of The Best Isles Plus Machu...

16 Days Lima to Quito

Operator: HX Expeditions

From 13,780pp
Save 2,206pp
Galápagos Islands – Iconic Wildlife & Sublime Scenery...

7 Days Quito to Quito

Operator: HX Expeditions

From 6,305pp
Save 1,240pp
Galápagos Islands – Iconic Wildlife & Sublime Scenery...

7 Days Quito to Quito

Operator: HX Expeditions

From 5,734pp
Save 1,345pp
Galápagos Islands – Iconic Wildlife & Sublime Scenery...

12 Days Lima to Quito

Operator: HX Expeditions

From 10,520pp
Save 1,277pp

Life On Board MS Santa Cruz II What can you expect when cruising on board MS Santa Cruz II

MS Santa Cruz II
MS Santa Cruz II

Embark on a sustainable and stylish Galápagos adventure aboard the MS Santa Cruz II and embrace the cozy atmosphere for an unforgettable experience. Read more

Unforgettable Expeditions
Unforgettable Expeditions

Explore the Galapagos Islands on an enticing and interesting expedition provided by your committed Expedition Team. Read more

The Science Corner
The Science Corner

The Science Corner includes a glass cabinet, a microscope and a whale vertebrae clone, a perfect learning zone about our science activities.

Gastronomic Delights
Gastronomic Delights

Savour the delightful cuisine and cocktails crafted by our dedicated staff on the MS Santa Cruz II, drawing from delicious local flavours and ingredients. Read more

Adventure is All-Inclusive
Adventure is All-Inclusive

Everything from daily excursions and activities to our onboard Science Centre, meals, gratuities, drinks and more. Read more

Wellness & Workouts
Wellness & Workouts

Enjoy exercise facilities to stay active and find moments of relaxation to rejuvenate both your body and mind. Read more

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Deck Plans

Ocean Deck
EH
Explorer Cabin
FH
Explorer Family Cabin
VH
Voyager Single Cabin
Horizon Deck
EE
Explorer Cabin
Expedition Deck
EP
Explorer Cabin
DS
Darwin suite
Panorama Deck
Sky Deck

Cabins

Oceanview

Voyager Single Cabin

With comfortable spaces and large picture windows to illuminate the interior spaces and allow guests to take in the views, these cabins offer single bed, and plenty of space for solo travelers. 12sqm.

Oceanview

Explorer Cabin

With comfortable spaces and large picture windows to illuminate the interior spaces and allow guests to take in the views, these cabins offer elegant areas to relax after a day of active exploring. The beds convert from double to twin upon request. 15sqm.

Oceanview

Explorer Family Cabin

With comfortable spaces and large picture windows to illuminate the interior spaces and allow guests to take in the views, these cabins offer elegant areas to relax after a day of active exploring. Cabins are equipped with twin beds and a sofa bed (ideal for children under 12). 18sqm.

Suite

Darwin suite

Our three Darwin suites on the Panorama deck feature double picture windows, and offers superb comfort and deluxe amenities. Available with a twin or double bed, and if more space is desired, these suites can be interconnected with an Explorer cabin. 30sqm.

MS Santa Cruz II Cruise Schedule All 173 cruise sailings by departure date on board MS Santa Cruz II

Starts
Days
Name
From - To
From
Starts
Saturday
08 Nov 2025
Days
14
Cruise Name
Nine Of The Best Isles - Plus Machu Picchu (Western And Northern Route)
From - To
Lima to Quito
From
15,660pp
Starts
Tuesday
11 Nov 2025
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,456pp
Starts
Tuesday
11 Nov 2025
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
12,550pp
Starts
Saturday
15 Nov 2025
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,832pp
Starts
Sunday
16 Nov 2025
Days
12
Cruise Name
In Darwin’s Footsteps Plus Machu Picchu (Eastern Route)
From - To
Lima to Quito
From
12,238pp
Starts
Wednesday
19 Nov 2025
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,128pp
Starts
Saturday
22 Nov 2025
Days
14
Cruise Name
Nine Of The Best Isles - Plus Machu Picchu (Western And Northern Route)
From - To
Lima to Quito
From
15,660pp
Starts
Tuesday
25 Nov 2025
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,832pp
Starts
Tuesday
25 Nov 2025
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
12,550pp
Starts
Saturday
29 Nov 2025
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,079pp
Starts
Sunday
30 Nov 2025
Days
12
Cruise Name
In Darwin’s Footsteps Plus Machu Picchu (Eastern Route)
From - To
Lima to Quito
From
12,239pp
Starts
Wednesday
03 Dec 2025
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,129pp
Starts
Saturday
06 Dec 2025
Days
10
Cruise Name
Iconic Wildlife & Sublime Scenery - Plus Machu Picchu (Western Route)
From - To
Lima to Quito
From
10,942pp
Starts
Saturday
06 Dec 2025
Days
14
Cruise Name
Nine Of The Best Isles - Plus Machu Picchu (Western And Northern Route)
From - To
Lima to Quito
From
15,660pp
Starts
Tuesday
09 Dec 2025
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,832pp
Starts
Tuesday
09 Dec 2025
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
12,550pp
Starts
Saturday
13 Dec 2025
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,079pp
Starts
Sunday
14 Dec 2025
Days
12
Cruise Name
In Darwin’s Footsteps Plus Machu Picchu (Eastern Route)
From - To
Lima to Quito
From
13,679pp
Starts
Wednesday
17 Dec 2025
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
10,569pp
Starts
Saturday
27 Dec 2025
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,694pp
Starts
Sunday
28 Dec 2025
Days
12
Cruise Name
In Darwin’s Footsteps Plus Machu Picchu (Eastern Route)
From - To
Lima to Quito
From
12,759pp
Starts
Wednesday
31 Dec 2025
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,649pp
Starts
Saturday
10 Jan 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,079pp
Starts
Sunday
11 Jan 2026
Days
12
Cruise Name
In Darwin’s Footsteps Plus Machu Picchu (Eastern Route)
From - To
Lima to Quito
From
12,759pp
Starts
Wednesday
14 Jan 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,649pp
Starts
Saturday
24 Jan 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,456pp
Starts
Tuesday
03 Feb 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,832pp
Starts
Tuesday
03 Feb 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
12,550pp
Starts
Saturday
07 Feb 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,832pp
Starts
Saturday
21 Feb 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,079pp
Starts
Wednesday
25 Feb 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
10,169pp
Starts
Tuesday
03 Mar 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,456pp
Starts
Saturday
07 Mar 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,079pp
Starts
Saturday
14 Mar 2026
Days
10
Cruise Name
Iconic Wildlife & Sublime Scenery - Plus Machu Picchu (Western Route)
From - To
Lima to Quito
From
10,189pp
Starts
Tuesday
17 Mar 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,079pp
Starts
Thursday
26 Mar 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
Starts
Thursday
26 Mar 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
16,393pp
Starts
Tuesday
31 Mar 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,490pp
Starts
Tuesday
31 Mar 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
12,243pp
Starts
Friday
03 Apr 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,659pp
Starts
Saturday
04 Apr 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,882pp
Starts
Wednesday
08 Apr 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,509pp
Starts
Thursday
09 Apr 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
Starts
Thursday
09 Apr 2026
Days
16
Cruise Name
Galápagos Islands - Nine Of The Best Isles Plus Machu Picchu
From - To
Lima to Quito
From
15,715pp
Starts
Tuesday
14 Apr 2026
Days
7
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route)
From - To
Quito to Quito
From
7,490pp
Starts
Tuesday
14 Apr 2026
Days
11
Cruise Name
Nine Of The Best Isles (Western And Northern Route)
From - To
Quito to Quito
From
11,565pp
Starts
Friday
17 Apr 2026
Days
14
Cruise Name
Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu
From - To
Lima to Quito
From
13,660pp
Starts
Saturday
18 Apr 2026
Days
7
Cruise Name
Nature And Wildlife Expedition Cruise (Northern Route)
From - To
Quito to Quito
From
7,490pp
Starts
Wednesday
22 Apr 2026
Days
9
Cruise Name
In Darwin’s Footsteps (Eastern Route)
From - To
Quito to Quito
From
9,510pp
Starts
Thursday
23 Apr 2026
Days
12
Cruise Name
Galápagos Islands – Iconic Wildlife & Sublime Scenery Plus Machu Picchu
From - To
Lima to Quito
From
11,640pp
View all MS Santa Cruz II Cruises
Cruise Content
Cabin images are sourced from HX Expeditions. These should be treated as indicative only. Cabin inclusions, upholsteries and room layout may differ to the image(s) shown depending on sailing dates.

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