All South America Tour & Cruise Packages

Compare 43 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
Filter Results
Departures
Show More...
Duration
7 Days
37 Days
Countries
Show More...
Budget
Ship Size
Start & End Cities
Operators
Show More...
Price
$7,200pp
$73,155pp
Filter Results
43 Packages (304 Package Departures)
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save (per person) 264
From (per person) 16,983
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departure: 01 March 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Brazil, Argentina, Uruguay, Falkland Islands (+2 more), Chile, Peru
Exclusive Deal
Save (per person) 1,544
From (per person) 17,851
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departure: 20 February 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save (per person) 1,546
From (per person) 17,649
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save (per person) 227
From (per person) 14,607
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Apr 2025 to Dec 2025
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Mar 2025 to Dec 2026
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 170
From (per person) 10,227
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Mar 2025 to Nov 2026
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 197
From (per person) 12,049
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Peru, Chile, Argentina
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$36,594
SUITE
$46,514
Save (per person) 6,816
From (per person) 36,594
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2026 to Oct 2026
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 25,790
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Departure: 28 February 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Chile, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$25,518
SUITE
$29,517
Save (per person) 6,707
From (per person) 25,518
New ReleaseTour + Cruise

34 Days Lima to Rio de Janeiro
Operated By: Scenic
Departure: 30 October 2025
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Peru, Argentina, Antarctica, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$52,476
SUITE
$57,946
Save (per person) 5,469
From (per person) 52,476
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$58,013
SUITE
$65,438
Save (per person) 7,052
From (per person) 58,013
Tour + Cruise

29 Days Lima to Rio de Janeiro
Operated By: APT
Departure: 08 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Peru, Argentina, Antarctica, Brazil
Fly Business Class + Save
Save (per person) 5,661
From (per person) 31,434
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2025 to Oct 2026
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 21,350
Tour + Cruise

32 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Antarctica, South Georgia Island, Falkland Islands (+1 more), Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$45,756
SUITE
$57,408
Save (per person) 13,424
From (per person) 45,756
Tour + Cruise

11 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Nov 2025 to Mar 2026
Trip Styles: Coach, Small Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Exclusive Savings
Save (per person) 286
From (per person) 11,902
Tour + Cruise

13 or 14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Dec 2024 to Mar 2026
Countries Visited: Argentina, Chile
Last Minute Deal
Save (per person) 409
From (per person) 11,600
Tour + Cruise

25 Days Lima to Buenos Aires
Operated By: Scenic
Departure: 30 October 2025
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Peru, Argentina, Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$42,993
SUITE
$48,463
Save (per person) 5,382
From (per person) 42,993
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save (per person) 252
From (per person) 16,348
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Departures: Feb 2026 to Jan 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$61,143
SUITE
$72,056
Save (per person) 5,594
From (per person) 61,143
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Jan 2025 to Nov 2025
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
New ReleaseTour + Cruise

26 Days Buenos Aires to Lima
Operated By: Scenic
Departure: 15 January 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Antarctica, Peru
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$44,924
SUITE
-
Save (per person) 5,401
From (per person) 44,924
Tour + Cruise

20 Days Buenos Aires to Rio de Janeiro
Operated By: APT
Departure: 17 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Argentina, Antarctica, Brazil
Fly Business Class + Save
Save (per person) 5,613
From (per person) 24,582
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$28,579
SUITE
$38,498
Save (per person) 6,746
From (per person) 28,579
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Aug 2025 to Sep 2025
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save (per person) 2,343
From (per person) 40,052
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Mar 2025 to Mar 2026
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 154
From (per person) 7,267
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Feb 2025 to Dec 2026
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 213
From (per person) 12,448
Tour + Cruise

22 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Departures: Jan 2025 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Antarctica, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$33,135
SUITE
$41,458
Save (per person) 5,341
From (per person) 33,135
Tour + Cruise

21 Days Rio de Janeiro to Buenos Aires
Operated By: Scenic
Departures: Dec 2025 to Jan 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Brazil, Argentina, Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$36,488
SUITE
$42,067
Save (per person) 5,378
From (per person) 36,488
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departures: Feb 2025 to Sep 2026
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 295
From (per person) 16,689
Results: 1-30 of 43

No Results found. Try changing your search filters.