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Tours from Rome to Palermo

Are you looking for a tour from Rome to Palermo? June is the most popular month to tour between Rome and Palermo and there are 188 departures available from five of the world's leading tour operators.
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11 Tours (188 Tour Departures)
17 Day Grand Italy & Sicily with Insight Vacations
Tour
 (12)

17 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Aug 2025 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Italy, Sicily
Mutiple Deals Available
Save (per person) 1,073
From (per person) 6,684
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14 Day Country Roads of Southern Italy & Sicily with Insight Vacations
Tour
 (8)

14 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Aug 2025 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Italy, Sicily
Mutiple Deals Available
Save (per person) 752
From (per person) 4,432
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14 Day Highlights of Sicily & Southern Italy with Globus
Tour
 (5)

14 Days Rome to Palermo
Operated By: Globus
Departures: Jul 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Italy, Sicily
Mutiple Deals Available
Save (per person) 322
From (per person) 3,772
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10 Day Southern Italy and Sicily with Trafalgar
Tour
 (2)

10 Days Rome to Palermo
Operated By: Trafalgar
Departures: Jul 2025 to Oct 2026
Trip Styles: Coach, Scenic
Countries Visited: Italy, Sicily
Mutiple Deals Available
Save (per person) 522
From (per person) 3,186
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22 Day Ultimate Italy with Contiki
Tour

22 Days Rome to Palermo
Operated By: Contiki
Departures: Aug 2025 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Countries Visited: Italy, Sicily
Ultimate Trip Offer
Save (per person) 712
From (per person) 4,426
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13 Day Italian Escape & Sicily with Contiki
Tour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Sep 2025 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Countries Visited: Italy, Sicily
Exclusive Savings
Save (per person) 262
From (per person) 3,247
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22 Day Ultimate Italy (Ages 27 to 35) with Contiki
Tour

22 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Countries Visited: Italy, Sicily
Ultimate Trip Offer
Save (per person) 595
From (per person) 4,560
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13 Day Italian Escape & Sicily (Ages 27 to 35) with Contiki
New ReleaseTour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Countries Visited: Italy, Sicily
Exclusive Savings
Save (per person) 66
From (per person) 3,247
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17 Day Grand Italy & Sicily (Small Group) with Insight Vacations
Tour

17 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Apr 2026 to Aug 2026
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Italy, Sicily
Sign Up SavingsPrice Drop Promise
Save (per person) 405
From (per person) 8,051
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14 Day Country Roads of Southern Italy & Sicily (Small Group) with Insight Vacations
Tour

14 Days Rome to Palermo
Operated By: Insight Vacations
Departure: 13 June 2026
Trip Styles: Coach, Small Group, Scenic
Countries Visited: Italy, Sicily
Sign Up SavingsPrice Drop Promise
Save (per person) 339
From (per person) 6,111
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23 Day Rome to Sicily with Intrepid Travel
Tour

23 Days Rome to Palermo
Operated By: Intrepid Travel
Departures: Aug 2025 to Oct 2027
Trip Styles: Adventure, Small Group
Countries Visited: Italy, Sicily
Exclusive Deal
Save (per person) 1,984
From (per person) 6,625
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Results: 11 results

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Italy & Sicily

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Travel Styles

18-30's Tours Active Adventures Coach Tours Cycling Tours Family Holidays Food & Wine Tours Kayaking Trips Locally Guided Tours Luxury Tours Rail Journeys Religious Tours Short Breaks Small Group Tours Walking & Hiking Tours Winter Tours & Trips

Trip Lengths

10 Day 2 Week 7 Day

Departure Months

July 2025 August 2025 September 2025 October 2025 November 2025 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 April 2027 May 2027 June 2027 July 2027 August 2027 September 2027 October 2027

Countries

Croatia France Greece Italy Malta Monaco Sicily Slovenia Switzerland Turkey

Cities

Rome

Routes

Tours from Rome to Palermo

Popular Italy Operators

Collette Italy Tours Cosmos Italy Tours Costsaver Italy Tours Exodus Italy Tours Explore's Italy Tours G Adventures Italy Tours Globus Italy Tours Insight Vacations Italy Tours Intrepid Italy Tours Topdeck Italy Tours Trafalgar Italy Tours

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