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Cruises From Manaus

Choose from 1 unique expeditions and cruises starting in Manaus, and travelling to Guayaquil. April, June and September are the most popular months to join a cruise from Manaus and you can select from 14 departures available from one leading cruise lines.
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1 Cruises (14 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save (per person) 264
From (per person) 16,983
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April 2025 June 2025 September 2025 November 2025 February 2026 April 2026 May 2026 June 2026 September 2026 October 2026 November 2026

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Manaus Rio de Janeiro Santos Sao Paulo

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