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MSC South America Cruises

MSC South America Cruises

Join MSC on one of 136 cruises visiting the coastal ports and cities of South America this season. January is the most popular month to begin your cruise and MSC have 369 cruises departing between December 2024 and April 2026.
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3 Days
102 Days
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$400pp
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136 Cruises (369 Cruise Departures)
11 Day South America with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 26 December 2025
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$2,589
OCEANVIEW
$3,074
BALCONY
$3,262
SUITE
$4,292
From (per person) 2,589
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 February 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$912
OCEANVIEW
$1,080
BALCONY
$1,318
SUITE
$2,436
From (per person) 912
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 March 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$1,351
OCEANVIEW
$1,529
BALCONY
$1,806
SUITE
$3,103
From (per person) 1,351
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Jan 2025 to Jan 2025
Countries Visited: Brazil, Argentina, Uruguay
Save And Sail Offer
INSIDE
$1,443
OCEANVIEW
$1,493
BALCONY
$1,938
SUITE
$3,364
From (per person) 1,443
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Sao Paulo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 18 April 2025
Countries Visited: Brazil, Spain
Last Minute DealEarly Booking Offer
INSIDE
$1,610
OCEANVIEW
$2,006
BALCONY
$2,550
SUITE
$4,025
From (per person) 1,610
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 13 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,259
OCEANVIEW
$1,526
BALCONY
$1,754
SUITE
$2,377
From (per person) 1,259
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 26 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$2,454
OCEANVIEW
$2,820
BALCONY
$3,117
SUITE
$3,899
From (per person) 2,454
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Barcelona to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 08 November 2025
Countries Visited: Spain, Gibraltar, Brazil, Uruguay
Early Booking Offer
INSIDE
$1,878
OCEANVIEW
$2,155
BALCONY
$2,432
SUITE
$4,323
From (per person) 1,878
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Jan 2025 to Feb 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$912
OCEANVIEW
$1,080
BALCONY
$1,318
SUITE
$2,436
From (per person) 912
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 28 December 2024
Countries Visited: Brazil
Save And Sail Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$3,255
SUITE
-
From (per person) 3,255
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 29 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$2,454
OCEANVIEW
$2,731
BALCONY
$3,117
SUITE
$4,622
From (per person) 2,454
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to São Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Jan 2025 to Mar 2025
Countries Visited: Brazil
Early Booking OfferSave And Sail Offer
INSIDE
$835
OCEANVIEW
$915
BALCONY
$1,103
SUITE
$1,548
From (per person) 835
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 20 March 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$786
OCEANVIEW
$915
BALCONY
$1,103
SUITE
$1,548
From (per person) 786
View Trip
11 Day South America with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 December 2025
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$2,708
OCEANVIEW
$3,074
BALCONY
$3,312
SUITE
$4,510
From (per person) 2,708
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2025 to Mar 2026
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$1,276
OCEANVIEW
$1,662
BALCONY
$1,820
SUITE
$2,642
From (per person) 1,276
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Sao Paulo to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 18 April 2025
Countries Visited: Brazil, Spain, France
Save And Sail OfferEarly Booking Offer
INSIDE
$2,108
OCEANVIEW
$2,415
BALCONY
$2,880
SUITE
$4,276
From (per person) 2,108
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$1,705
OCEANVIEW
$2,041
BALCONY
$2,269
SUITE
$3,358
From (per person) 1,705
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 05 January 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,159
OCEANVIEW
$1,406
BALCONY
$1,901
SUITE
$2,911
From (per person) 1,159
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

19 Days (18 Nights) Sao Paulo to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 18 April 2025
Countries Visited: Brazil, Spain, France, Italy
Save And Sail OfferEarly Booking Offer
INSIDE
-
OCEANVIEW
$2,399
BALCONY
$3,102
SUITE
$4,497
From (per person) 2,399
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar, France (+1 more), Italy
Early Booking Offer
INSIDE
$2,197
OCEANVIEW
$2,504
BALCONY
$3,069
SUITE
$4,771
From (per person) 2,197
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$1,616
OCEANVIEW
$2,041
BALCONY
$2,219
SUITE
$3,150
From (per person) 1,616
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2025 to Mar 2026
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$1,375
OCEANVIEW
$1,662
BALCONY
$1,850
SUITE
$2,820
From (per person) 1,375
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar, France
Early Booking Offer
INSIDE
$2,065
OCEANVIEW
$2,372
BALCONY
$2,906
SUITE
$4,520
From (per person) 2,065
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 March 2026
Countries Visited: Argentina, Brazil, Spain, Morocco
Early Booking Offer
INSIDE
$2,392
OCEANVIEW
$2,699
BALCONY
$3,055
SUITE
$4,946
From (per person) 2,392
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Barcelona to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 08 November 2025
Countries Visited: Spain, Gibraltar, Brazil, Uruguay (+1 more), Argentina
Early Booking Offer
INSIDE
$2,005
OCEANVIEW
$2,302
BALCONY
$2,589
SUITE
$4,252
From (per person) 2,005
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 08 February 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$1,054
OCEANVIEW
$1,252
BALCONY
$1,529
SUITE
$2,826
From (per person) 1,054
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 16 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,259
OCEANVIEW
$1,526
BALCONY
$1,754
SUITE
-
From (per person) 1,259
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

19 Days (18 Nights) Buenos Aires to Valencia
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 March 2026
Countries Visited: Argentina, Brazil, Spain, Morocco
Early Booking Offer
INSIDE
$2,260
OCEANVIEW
$2,557
BALCONY
$2,894
SUITE
-
From (per person) 2,260
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Jan 2025 to Mar 2025
Countries Visited: Brazil, Uruguay, Argentina
Save And Sail Offer
INSIDE
$1,143
OCEANVIEW
$1,371
BALCONY
$1,707
SUITE
$2,371
From (per person) 1,143
View Trip
19 Day Mediterranean with MSC Cruises
Cruise
 (1)

19 Days (18 Nights) Rome to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 06 November 2025
Countries Visited: Italy, Spain, Gibraltar, Brazil (+2 more), Uruguay, Argentina
Early Booking Offer
INSIDE
$2,229
OCEANVIEW
$2,576
BALCONY
$2,913
SUITE
$4,784
From (per person) 2,229
View Trip
Results: 1-30 of 136

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