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River Cruises from Ho Chi Minh City to Siem Reap

Are you looking for a river cruise from Ho Chi Minh City to Siem Reap? March and April are the most popular months to river cruise between Ho Chi Minh City and Siem Reap and there are 191 departures available from four of the world's leading river cruise lines.
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Duration
8 Days
15 Days
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Price
$2,800pp
$18,955pp
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11 River Cruises (191 River Cruise Departures)
13 Day Treasures of the Mekong with Scenic
River Cruise
 (1)

13 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ships: Scenic Spirit
Departures: Apr 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Fly Free Economy2 for 1 Fares + Fly Free Premium Economy
INSIDE
-
RIVER VIEW
-
BALCONY
$7,250
SUITE
$10,360
Save (per person) 8,425
From (per person) 7,250
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Ho Chi Minh City to Siem Reap
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$5,755
BALCONY
$6,255
SUITE
$8,555
Save (per person) 5,795
From (per person) 5,755
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$5,255
BALCONY
$5,755
SUITE
$8,555
Save (per person) 5,995
From (per person) 5,255
View Trip
10 Day Charms of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
INSIDE
-
RIVER VIEW
-
BALCONY
$3,248
SUITE
$4,947
From (per person) 3,248
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Aug 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Fly Free Economy2 for 1 Fares + Fly Free Premium Economy
INSIDE
-
RIVER VIEW
-
BALCONY
$6,690
SUITE
$9,995
Save (per person) 8,320
From (per person) 6,690
View Trip
12 Day Charms of the Mekong with Ho Chi Minh City and Siem Reap with AmaWaterways
New ReleaseRiver Cruise

12 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
INSIDE
-
RIVER VIEW
-
BALCONY
$3,947
SUITE
$5,646
From (per person) 3,947
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Fly Free Economy2 for 1 Fares + Fly Free Premium Economy
INSIDE
-
RIVER VIEW
-
BALCONY
$7,350
SUITE
$10,655
Save (per person) 8,320
From (per person) 7,350
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ships: Scenic Spirit
Departures: Apr 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Fly Free Economy2 for 1 Fares + Fly Free Premium Economy
INSIDE
-
RIVER VIEW
-
BALCONY
$6,590
SUITE
$9,725
Save (per person) 8,425
From (per person) 6,590
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
INSIDE
-
RIVER VIEW
-
BALCONY
$2,849
SUITE
$4,548
From (per person) 2,849
View Trip
10 Day Charms of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
INSIDE
-
RIVER VIEW
-
BALCONY
$3,548
SUITE
$5,247
From (per person) 3,548
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2025 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Avalon Exclusive
INSIDE
-
RIVER VIEW
-
BALCONY
-
SUITE
$5,119
Save (per person) 2,055
From (per person) 4,446
View Trip
Results: 11 results

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