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River Cruises from Siem Reap to Ho Chi Minh City

Are you looking for a river cruise from Siem Reap to Ho Chi Minh City? January, February and March are the most popular months to river cruise between Siem Reap and Ho Chi Minh City and there are 310 departures available from six of the world's leading river cruise lines.
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Duration
8 Days
15 Days
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Price
$2,700pp
$14,575pp
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15 River Cruises (310 River Cruise Departures)
12 Day Essential Vietnam and Cambodia with Travelmarvel
River Cruise
 (6)

12 Days Siem Reap to Ho Chi Minh City
Operated By: Travelmarvel
Ship: RV Apsara
Departures: Aug 2025 to Mar 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$4,259
SUITE
$6,234
Save (per person) 1,547
From (per person) 4,259
View Trip
11 Day Spiritual Cambodia and The Mekong with APT
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Operated By: APT
Ship: Mekong Serenity
Departures: Jul 2025 to Apr 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$6,437
SUITE
$8,313
Save (per person) 771
From (per person) 6,437
View Trip
13 Day Vietnam and Cambodia Highlights with APT
River Cruise
 (3)

13 Days Siem Reap to Ho Chi Minh City
Operated By: APT
Ship: Mekong Serenity
Departures: Jul 2025 to Apr 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$7,428
SUITE
$9,304
Save (per person) 1,582
From (per person) 7,428
View Trip
8 Day Majestic Mekong Cruising with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operated By: Travelmarvel
Ships: RV Apsara
Departures: Jan 2025 to Mar 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$2,719
SUITE
$4,946
Save (per person) 2,021
From (per person) 2,719
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Jan 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$5,197
BALCONY
$6,068
SUITE
$8,815
Save (per person) 1,563
From (per person) 5,197
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Siem Reap to Ho Chi Minh City
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Super EarlybirdSuper Earlybird: No Single Supplement
INSIDE
-
RIVER VIEW
$4,951
BALCONY
$5,822
SUITE
$7,955
Save (per person) 2,251
From (per person) 4,951
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Feb 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
Save (per person) 3,084
From (per person) 6,580
View Trip
11 Day Temple Discovery and Luxury Mekong Cruise with Scenic
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ships: Scenic Spirit
Departures: Jan 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Mutiple Deals Available
INSIDE
-
RIVER VIEW
-
BALCONY
$8,207
SUITE
$11,068
Save (per person) 1,607
From (per person) 8,207
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Anniversary SaleSummer Triple Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$3,583
SUITE
$6,104
Save (per person) 1,168
From (per person) 3,583
View Trip
13 Day Riches of the Mekong with Siem Reap and Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Summer Triple Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$5,071
SUITE
$7,593
Save (per person) 1,183
From (per person) 5,071
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Super EarlybirdReduced Single Supplement
INSIDE
-
RIVER VIEW
-
BALCONY
$7,327
SUITE
$10,188
Save (per person) 4,589
From (per person) 7,327
View Trip
10 Day Riches of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to May 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Summer Triple Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$3,841
SUITE
$6,362
Save (per person) 1,171
From (per person) 3,841
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Super EarlybirdReduced Single Supplement
INSIDE
-
RIVER VIEW
-
BALCONY
$7,317
SUITE
$10,178
Save (per person) 3,589
From (per person) 7,317
View Trip
11 Day Riches of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

11 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Summer Triple Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$4,449
SUITE
$6,970
Save (per person) 1,177
From (per person) 4,449
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ships: Scenic Spirit
Departures: Jan 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Mutiple Deals Available
INSIDE
-
RIVER VIEW
-
BALCONY
$8,217
SUITE
$11,078
Save (per person) 2,607
From (per person) 8,217
View Trip
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River Cruises from Siem Reap to Ho Chi Minh City

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