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River Cruises from Siem Reap to Ho Chi Minh City

Are you looking for a river cruise from Siem Reap to Ho Chi Minh City? January, April and September are the most popular months to river cruise between Siem Reap and Ho Chi Minh City and there are 214 departures available from four of the world's leading river cruise lines.
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Duration
8 Days
15 Days
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Price
$2,800pp
$22,255pp
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11 River Cruises (214 River Cruise Departures)
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$5,755
BALCONY
$6,255
SUITE
$8,555
Save (per person) 6,320
From (per person) 5,755
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
2 for 1 Fares + Fly Free Economy2 for 1 Fares + Fly Free Premium Economy
INSIDE
-
RIVER VIEW
-
BALCONY
$7,350
SUITE
$10,655
Save (per person) 8,120
From (per person) 7,350
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
2 for 1 Fares + Fly Free Economy2 for 1 Fares + Fly Free Premium Economy
INSIDE
-
RIVER VIEW
-
BALCONY
$6,690
SUITE
$9,995
Save (per person) 8,120
From (per person) 6,690
View Trip
10 Day Riches of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to May 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
INSIDE
-
RIVER VIEW
-
BALCONY
$3,248
SUITE
$4,947
From (per person) 3,248
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
INSIDE
-
RIVER VIEW
-
BALCONY
$2,849
SUITE
$4,548
From (per person) 2,849
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Avalon Exclusive
INSIDE
-
RIVER VIEW
-
BALCONY
-
SUITE
$4,386
Save (per person) 2,056
From (per person) 4,386
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Siem Reap to Ho Chi Minh City
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$5,255
BALCONY
$5,755
SUITE
$8,555
Save (per person) 5,495
From (per person) 5,255
View Trip
11 Day Temple Discovery and Luxury Mekong Cruise with Scenic
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ships: Scenic Spirit
Departures: Apr 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Mutiple Deals Available
INSIDE
-
RIVER VIEW
-
BALCONY
$6,590
SUITE
$9,325
Save (per person) 10,075
From (per person) 6,590
View Trip
13 Day Riches of the Mekong with Siem Reap and Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
INSIDE
-
RIVER VIEW
-
BALCONY
$4,047
SUITE
$5,746
From (per person) 4,047
View Trip
11 Day Riches of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

11 Days Siem Reap to Ho Chi Minh City
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
INSIDE
-
RIVER VIEW
-
BALCONY
$3,648
SUITE
$5,347
From (per person) 3,648
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ships: Scenic Spirit
Departures: Apr 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Mutiple Deals Available
INSIDE
-
RIVER VIEW
-
BALCONY
$7,250
SUITE
$9,960
Save (per person) 10,075
From (per person) 7,250
View Trip
Results: 11 results

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River Cruises from Siem Reap to Ho Chi Minh City

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