South America Tours Starting In April 2026

If you're looking at joining a tour through South America in April 2026, we have 183 unique tours and small group adventures with 12,875 departures from the world's leading tour operators departing in April.
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Departures (April 2026)
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3 Days
65 Days
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$400pp
$100,565pp
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183 Tours (12,875 Tour Departures)
Tour
 (13)

19 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Deal
Save (per person) 150
From (per person) 5,070
Tour
 (3)

12 Days Lima to Lima
Operated By: Globus
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Peru
Your Wow Starts Now
Save (per person) 500
From (per person) 5,047
Tour
 (3)

22 Days Rio de Janeiro to Lima
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Your Wow Starts Now
Save (per person) 500
From (per person) 9,505
Tour
 (3)

23 Days Manaus to Lima
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru
From (per person) 6,832
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
From (per person) 11,484
Tour
 (2)

20 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
From (per person) 5,627
Tour
 (2)

8 Days Lima to Lima
Operated By: Trafalgar
Departures: May 2025 to Dec 2026
Trip Styles: Coach, Scenic
Countries Visited: Peru
Today's DealLast Minute Deal
Save (per person) 256
From (per person) 3,350
Tour
 (2)

8 Days Lima to Lima
Operated By: Globus
Departures: Apr 2025 to Dec 2026
Trip Styles: Coach, Scenic
Countries Visited: Peru
Your Wow Starts Now
Save (per person) 500
From (per person) 2,872
Tour
 (2)

26 Days Manaus to Lima
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
From (per person) 11,692
Tour
 (1)

21 Days Lima to Lima
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Trip Styles: Adventure, Small Group, Walking & Hiking, Wildlife, Inca Trail
Countries Visited: Peru
Latest Offer
Save (per person) 980
From (per person) 3,909
Tour
 (1)

18 Days Santiago to Rio de Janeiro
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile, Brazil
Latest Offer
Save (per person) 847
From (per person) 4,377
Tour
 (1)

24 Days Manaus to Lima
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
From (per person) 7,203
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Countries Visited: Ecuador, Galapagos
Last Minute OfferLatest Offer
Save (per person) 900
From (per person) 2,699
Tour
 (1)

23 Days Lima to Rio de Janeiro
Operated By: Luxury Gold
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Peru, Chile, Argentina, Brazil
From (per person) 17,350
Tour
 (1)

9 Days Buenos Aires to Rio de Janeiro
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Brazil
Latest Offer
Save (per person) 610
From (per person) 2,439
Tour
 (1)

4 Days Iguazu Falls to Iguazu Falls
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Trip Styles: Adventure, Short Break
Countries Visited: Argentina, Brazil
From (per person) 539
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Trip Styles: Adventure, Small Group, Wildlife
Countries Visited: Ecuador
Last Minute Offer
Save (per person) 225
From (per person) 2,024
Tour
 (1)

9 Days Rio de Janeiro to Buenos Aires
Operated By: Costsaver
Departures: May 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Brazil, Argentina
Last Minute DealToday's Deal
Save (per person) 170
From (per person) 2,325
Tour
 (1)

12 Days Rio de Janeiro to Santiago
Operated By: Globus
Departures: Jun 2025 to Dec 2026
Trip Styles: Coach, Scenic
Countries Visited: Brazil, Argentina, Chile
Your Wow Starts Now
Save (per person) 500
From (per person) 4,813
Tour
 (1)

23 Days Manaus to Santiago
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Chile, Easter Island
From (per person) 11,821
Tour
 (1)

6 Days Puerto Natales to Puerto Natales
Operated By: G Adventures
Departures: Mar 2025 to Apr 2027
Countries Visited: Chile
Last Minute Offer
Save (per person) 670
From (per person) 2,679
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
From (per person) 9,878
New ReleaseTour
 (1)

11 Days Cusco to Cusco
Operated By: Crooked Compass
Departures: Apr 2025 to Oct 2026
Trip Styles: Adventure, Small Group, Walking & Hiking, Cultural, Off The Beaten Track
Countries Visited: Peru
From (per person) 6,243
River Cruise

16 Days Lima to Lima
Ships: Aria Amazon
Departures: May 2025 to Dec 2026
Rivers: Amazon
Countries Visited: Peru
Earlybird SavingSail Into Savings
Save (per person) 1,650
From (per person) 13,049
Tour

16 Days Manaus to Santiago
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Chile
From (per person) 7,079
Tour

8 Days Quito to Quito
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Trip Styles: Adventure, Small Group
Countries Visited: Ecuador
Latest Offer
Save (per person) 195
From (per person) 892
Tour

12 Days Rio de Janeiro to Santiago
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Scenic
Countries Visited: Brazil, Argentina, Chile
Exclusive Deal
Save (per person) 150
From (per person) 3,273
Tour

15 Days Quito to Lima
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Trip Styles: Adventure, Small Group, 18-30's
Countries Visited: Ecuador, Peru
Latest Offer
Save (per person) 297
From (per person) 1,452
Tour

19 Days Manaus to Santiago
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Chile
From (per person) 8,907
Tour

10 Days Quito to Papallacta
Operated By: G Adventures
Departures: Mar 2025 to Dec 2026
Countries Visited: Ecuador, Galapagos
Last Minute OfferLatest Offer
Save (per person) 1,380
From (per person) 3,219
Results: 1-30 of 183

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