Sicily Cruises Starting In October 2025

If you're looking at joining a cruise to Sicily in October 2025, we have 8 unique cruise itineraries and 71 departures available, operated by six of the world's leading cruise lines departing in October.
Filter Results
Departures (October 2025)
Duration
4 Days
12 Days
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$100pp
$33,610pp
Countries
Show More...
Filter Results
8 Cruises (71 Cruise Departures)
Cruise

4 Days (3 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Departure: 01 October 2025
Countries Visited: Sicily, Malta, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$469
SUITE
$739
From (per person) 469
Cruise
 (2)

9 Days (8 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 09 October 2025
Countries Visited: Italy, Sicily, Greece
INSIDE
-
OCEANVIEW
-
BALCONY
$6,570
SUITE
$12,240
From (per person) 6,570
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Departures: Oct 2025 to Oct 2026
Countries Visited: Italy, Sicily, Greece
March Vacation SaleExclusive Solo Offer
INSIDE
$1,285
OCEANVIEW
$1,496
BALCONY
$1,559
SUITE
$2,355
Save (per person) 916
From (per person) 1,285
Cruise
 (5)

8 Days (7 Nights) Venice to Rome
Operated By: Viking Cruises
Departures: Aug 2025 to Aug 2027
Countries Visited: Italy, Croatia, Sicily
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$3,349
SUITE
$4,499
Save (per person) 550
From (per person) 3,349
Cruise

12 Days (11 Nights) Rome to Malta
Operated By: Tauck
Departures: Jun 2025 to Oct 2026
Countries Visited: Italy, Sicily, Malta
Complimentary Hotel Night
From (per person) 11,990
Cruise
 (7)

8 Days (7 Nights) Rome to Venice
Operated By: Viking Cruises
Departures: Apr 2025 to Jul 2027
Countries Visited: Italy, Sicily, Croatia
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$3,599
SUITE
$4,499
Save (per person) 500
From (per person) 3,599
Cruise

12 Days (11 Nights) Malta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2026
Countries Visited: Malta, Sicily, Italy
Complimentary Hotel Night
From (per person) 12,490
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Departures: Oct 2025 to Oct 2026
Countries Visited: Greece, Sicily, Spain
Sail Into Deeper Savings Best Rate
INSIDE
$1,207
OCEANVIEW
$1,417
BALCONY
$1,635
SUITE
$4,095
From (per person) 1,207
Results: 8 results

No Results found. Try changing your search filters.

Trip Lengths

Cities