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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 331 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. September is the most popular month to cruise to Sicily and we have over 2,025 departures available from twenty-two of the world's leading cruise lines.
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29 Days
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331 Cruises (2,025 Cruise Departures)
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) La Goulette to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 31 July 2025
Countries Visited: Tunisia, Sicily
Exclusive Deal
INSIDE
$326
OCEANVIEW
-
BALCONY
$425
SUITE
-
From (per person) 326
View Trip
8 Day Mediterranean Cruise: Italy & Greece with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 December 2026
Countries Visited: Italy, Sicily, Greece
INSIDE
$2,444
OCEANVIEW
$2,820
BALCONY
$3,622
SUITE
$5,691
From (per person) 2,444
View Trip
9 Day Mind and Taste Buds Awake with the Mucem in the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 09 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,695
SUITE
$16,417
Save (per person) 165
From (per person) 8,695
View Trip
9 Day A Circumnavigation of Sicily - with Smithsonian Journeys with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Jun 2025 to Aug 2026
Countries Visited: Malta, Sicily, Tunisia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,694
SUITE
$18,103
Save (per person) 674
From (per person) 10,694
View Trip
9 Day Epicurean Delights of Sicily and the Adriatic Coast of Italy with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 10 June 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,606
SUITE
$17,799
Save (per person) 184
From (per person) 9,606
View Trip
13 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

13 Days (12 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 11 April 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,338
OCEANVIEW
$5,675
BALCONY
-
SUITE
-
From (per person) 5,338
View Trip
11 Day Mediterranean Crossroads with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Athens to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 09 November 2025
Countries Visited: Greece, Sicily, Malta
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,718
Save (per person) 3,127
From (per person) 13,718
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 22 September 2025
Countries Visited: Italy, Greece, Sicily
INSIDE
$4,033
OCEANVIEW
-
BALCONY
$5,638
SUITE
$6,633
From (per person) 4,033
View Trip
8 Day Iberian Peninsula & Sicily with Ponant
Cruise
 (1)

8 Days (7 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 28 April 2026
Countries Visited: Spain, Sicily, Malta
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,665
SUITE
$12,515
Save (per person) 125
From (per person) 6,665
View Trip
8 Day Glorious Greek Isles to Spanish Sunsets with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ships: Resilient Lady, Scarlet Lady
Departures: Oct 2025 to Oct 2026
Countries Visited: Greece, Sicily, Spain
80% Off Second SailorUp To USD $300 Bar Tab
INSIDE
$1,928
OCEANVIEW
$2,270
BALCONY
$2,612
SUITE
$6,665
From (per person) 1,928
View Trip
12 Day Italy Cruise: Venice, Sicily & Rome with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 August 2026
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,209
OCEANVIEW
$5,971
BALCONY
$7,496
SUITE
$10,139
From (per person) 5,209
View Trip
8 Day Hidden Gems of Italy with Travelmarvel
New ReleaseCruise

8 Days (7 Nights) Valletta to Venice
Operated By: Travelmarvel
Departure: 05 May 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Deal
Save (per person) 2,538
From (per person) 4,452
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: May 2025 to Aug 2027
Countries Visited: Italy, Croatia, Sicily
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$6,071
SUITE
$9,301
Save (per person) 664
From (per person) 6,071
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 16 April 2025
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
$578
OCEANVIEW
$756
BALCONY
$825
SUITE
$1,350
From (per person) 578
View Trip
11 Day Ancient Civilisations, from Italy to Greece with Ponant
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Champlain
Departure: 01 October 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,785
SUITE
$20,330
Save (per person) 205
From (per person) 10,785
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 01 October 2025
Countries Visited: Sicily, Malta, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$837
SUITE
$1,293
From (per person) 837
View Trip
9 Day Cruising Southern Italy and Sicily - with Smithsonian Journeys with Ponant
Cruise

9 Days (8 Nights) Valletta to Livorno
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departures: Aug 2025 to Sep 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,517
SUITE
$17,740
Save (per person) 221
From (per person) 10,517
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
Super Earlybird
INSIDE
-
OCEANVIEW
$9,761
BALCONY
-
SUITE
$13,276
Save (per person) 2,084
From (per person) 9,761
View Trip
8 Day A Journey Through Europe’s Finest From Opulence To Artistic Splendor with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 25 May 2026
Countries Visited: Monaco, Italy, Sicily, Spain
Unique Oceans OfferExplora Early Booking Benefit
INSIDE
-
OCEANVIEW
-
BALCONY
$7,311
SUITE
$8,390
From (per person) 7,311
View Trip
11 Day Mediterranean Delights with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 20 July 2026
Countries Visited: Malta, Sicily, Tunisia
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,565
Save (per person) 3,130
From (per person) 14,565
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vesta
Departures: Mar 2025 to Jul 2027
Countries Visited: Italy, Sicily, Croatia
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$6,071
SUITE
$8,311
Save (per person) 1,669
From (per person) 6,071
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: Oct 2025 to Oct 2026
Countries Visited: Italy, Sicily, Greece
Exclusive DealSingle Savings
INSIDE
$1,823
OCEANVIEW
$2,153
BALCONY
$2,276
SUITE
$3,472
Save (per person) 1,065
From (per person) 1,823
View Trip
11 Day 5th Opera Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 22 June 2026
Countries Visited: Italy, Sicily, France
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$12,676
SUITE
$23,868
Save (per person) 244
From (per person) 12,676
View Trip
8 Day Italian & Aegean Sampler with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,050
SUITE
-
Save (per person) 2,040
From (per person) 5,050
View Trip
8 Day Island Odyssey: Malta, Sicily & the Greek Isles with Scenic
New ReleaseCruise

8 Days (7 Nights) Valletta to Athens
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 June 2026
Countries Visited: Malta, Sicily, Greece
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$12,477
SUITE
$16,190
Save (per person) 3,113
From (per person) 12,477
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Palermo to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 12 November 2025
Countries Visited: Sicily, Spain, Brazil
Early Booking Offer
INSIDE
$2,124
OCEANVIEW
$2,331
BALCONY
$3,104
SUITE
$3,995
From (per person) 2,124
View Trip
8 Day Italian Treasures: Amalfi Coast, Sicily and Malta with Scenic
New ReleaseCruise

8 Days (7 Nights) Rome to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 07 June 2026
Countries Visited: Italy, Sicily, Malta
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$12,627
SUITE
$30,932
Save (per person) 3,113
From (per person) 12,627
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$857
SUITE
$2,162
From (per person) 857
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Countries Visited: Malta, Sicily, Italy
From (per person) 18,940
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,754
Save (per person) 851
From (per person) 10,754
View Trip
Results: 1-30 of 331

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