Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 331 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. September is the most popular month to cruise to Sicily and we have over 1,829 departures available from twenty-two of the world's leading cruise lines.
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2 Days
29 Days
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$34,310pp
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331 Cruises (1,829 Cruise Departures)
Cruise

2 Days (1 Nights) La Goulette to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 31 July 2025
Countries Visited: Tunisia, Sicily
Exclusive Deal
INSIDE
$326
OCEANVIEW
-
BALCONY
$425
SUITE
-
From (per person) 326
Cruise
 (2)

9 Days (8 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 09 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,214
SUITE
$15,486
Save (per person) 156
From (per person) 8,214
New ReleaseCruise
 (3)

11 Days (10 Nights) Athens to Valletta
Cruise Line: Emerald Cruises
Departure: 09 November 2025
Countries Visited: Greece, Sicily, Malta
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,718
Save (per person) 3,127
From (per person) 13,718
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Departure: 10 June 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$11,439
SUITE
$21,278
Save (per person) 221
From (per person) 11,439
Cruise
 (2)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Departure: 15 August 2025
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$1,482
OCEANVIEW
$1,544
BALCONY
$1,647
SUITE
$3,618
Save (per person) 803
From (per person) 1,482
Cruise
 (1)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Departures: Jun 2025 to Aug 2026
Countries Visited: Malta, Sicily, Tunisia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,694
SUITE
$18,103
Save (per person) 674
From (per person) 10,694
Cruise
 (1)

13 Days (12 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Departure: 11 April 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,685
OCEANVIEW
$6,120
BALCONY
$6,853
SUITE
$11,852
From (per person) 5,685
Cruise
 (1)

4 Days (3 Nights) Genoa to Valletta
Cruise Line: MSC Cruises
Departure: 13 April 2025
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$2,380
From (per person) 2,380
Cruise
 (5)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Departures: Oct 2025 to Oct 2026
Countries Visited: Greece, Sicily, Spain
Limited Time Offer
INSIDE
$1,853
OCEANVIEW
$2,182
BALCONY
$2,511
SUITE
$6,414
From (per person) 1,853
Cruise
 (3)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Departure: 22 August 2026
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,209
OCEANVIEW
$5,971
BALCONY
$7,496
SUITE
$10,139
From (per person) 5,209
Cruise
 (1)

8 Days (7 Nights) Malaga to Valletta
Cruise Line: Ponant
Departure: 28 April 2026
Countries Visited: Spain, Sicily, Malta
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,665
SUITE
$12,515
Save (per person) 125
From (per person) 6,665
Cruise
 (1)

10 Days (9 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Departure: 22 September 2025
Countries Visited: Italy, Greece, Sicily
INSIDE
$3,880
OCEANVIEW
-
BALCONY
$5,471
SUITE
$6,404
From (per person) 3,880
Cruise

8 Days (7 Nights) Valletta to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 25 September 2025
Countries Visited: Malta, Croatia, Sicily
Latest Offer
INSIDE
$2,001
OCEANVIEW
$2,566
BALCONY
$3,089
SUITE
$4,861
From (per person) 2,001
New ReleaseCruise

8 Days (7 Nights) Valletta to Venice
Operated By: Travelmarvel
Departure: 05 May 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Deal
Save (per person) 1,840
From (per person) 4,655
Cruise

12 Days (11 Nights) Rome to Valletta
Operated By: Tauck
Departures: Jun 2025 to Oct 2025
Countries Visited: Italy, Sicily, Malta
From (per person) 18,170
New ReleaseCruise

8 Days (7 Nights) Rome to Valletta
Cruise Line: Scenic
Departure: 07 June 2026
Countries Visited: Italy, Sicily, Malta
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$12,627
SUITE
$30,932
Save (per person) 3,113
From (per person) 12,627
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Champlain
Departure: 01 October 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,785
SUITE
$20,330
Save (per person) 205
From (per person) 10,785
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Departure: 20 July 2026
Countries Visited: Malta, Sicily, Tunisia
Super Earlybird
INSIDE
-
OCEANVIEW
$10,605
BALCONY
-
SUITE
$14,565
Save (per person) 2,590
From (per person) 10,605
Cruise

5 Days (4 Nights) Barcelona to Valletta
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 18 April 2025
Countries Visited: Spain, Sicily, Malta
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$3,361
SUITE
$3,777
From (per person) 3,361
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 31 August 2026
Countries Visited: Italy, Sicily, Greece
INSIDE
$2,804
OCEANVIEW
$3,273
BALCONY
$3,743
SUITE
$9,162
From (per person) 2,804
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 25 May 2026
Countries Visited: Monaco, Italy, Sicily, Spain
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$7,311
SUITE
$8,390
From (per person) 7,311
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
Super Earlybird
INSIDE
-
OCEANVIEW
$9,761
BALCONY
-
SUITE
$13,276
Save (per person) 2,084
From (per person) 9,761
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Departures: Oct 2025 to Oct 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
$1,873
OCEANVIEW
$2,155
BALCONY
$2,261
SUITE
$3,394
Save (per person) 1,063
From (per person) 1,873
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Departures: May 2025 to Aug 2027
Countries Visited: Italy, Croatia, Sicily
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$6,071
SUITE
$9,301
Save (per person) 664
From (per person) 6,071
New ReleaseTour + Cruise

16 Days Venice to Valletta
Operated By: Scenic
Departure: 30 May 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Italy, Sicily, Malta
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$28,215
SUITE
$46,520
Save (per person) 3,270
From (per person) 28,215
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Countries Visited: Malta, Sicily, Italy
From (per person) 18,940
New ReleaseCruise

8 Days (7 Nights) Valletta to Athens
Cruise Line: Scenic
Departure: 14 June 2026
Countries Visited: Malta, Sicily, Greece
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$12,477
SUITE
$16,190
Save (per person) 3,113
From (per person) 12,477
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$837
SUITE
$2,162
From (per person) 837
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Departures: May 2026 to Jul 2026
Countries Visited: Malta, Sicily, Italy
Super Earlybird
INSIDE
-
OCEANVIEW
$9,761
BALCONY
-
SUITE
$13,276
Save (per person) 2,088
From (per person) 9,761
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Departure: 22 June 2026
Countries Visited: Italy, Sicily, France
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$12,676
SUITE
$23,868
Save (per person) 244
From (per person) 12,676
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