Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 50 unique cruise itineraries from 4 leading cruise lines. April is the most popular month to join a short cruise break sailing in and around the Mediterranean with 74 departures starting between January 2025 and May 2026.
Filter Results
Departures
Show More...
Duration
2 Days
5 Days
Start & End Cities
Ship Size
Cruise Lines
Price
$200pp
$9,735pp
Countries
Show More...
Filter Results
50 Cruises (74 Cruise Departures)
Cruise
 (1)

5 Days (4 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2025 to Feb 2025
Countries Visited: Italy, Sicily, Tunisia, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$726
SUITE
-
From (per person) 726
Cruise
 (1)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Departures: Apr 2025 to May 2026
Countries Visited: Turkey, Greece, Italy
Exclusive Deal
INSIDE
$431
OCEANVIEW
$560
BALCONY
$738
SUITE
$995
From (per person) 431
Cruise
 (1)

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2025 to Apr 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$314
OCEANVIEW
$393
BALCONY
$492
SUITE
-
From (per person) 314
Cruise
 (1)

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2025 to Apr 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$847
OCEANVIEW
$540
BALCONY
$679
SUITE
$1,471
From (per person) 540
Cruise
 (1)

3 Days (2 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 14 April 2025
Countries Visited: Italy, France
Exclusive Deal
INSIDE
$453
OCEANVIEW
$502
BALCONY
$591
SUITE
$978
From (per person) 453
Cruise
 (2)

5 Days (4 Nights) Valletta to Genoa
Cruise Line: MSC Cruises
Departure: 05 November 2025
Countries Visited: Malta, Spain, France, Italy
Exclusive Deal
INSIDE
$746
OCEANVIEW
$875
BALCONY
$1,004
SUITE
-
From (per person) 746
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Departures: Apr 2025 to Nov 2025
Countries Visited: Spain, France, Italy
Early Booking OfferSave And Sail Offer
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,221
From (per person) 608
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 27 April 2026
Countries Visited: France, Italy, Spain
Early Booking Offer
INSIDE
$1,014
OCEANVIEW
$1,133
BALCONY
$1,222
SUITE
$1,657
From (per person) 1,014
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Departure: 16 April 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$512
BALCONY
$621
SUITE
$1,017
From (per person) 512
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Countries Visited: Italy, Spain, France
Early Booking Offer
INSIDE
$994
OCEANVIEW
$1,113
BALCONY
$1,202
SUITE
$1,637
From (per person) 994
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Departures: Apr 2025 to Nov 2025
Countries Visited: Italy, Spain, France
Early Booking OfferExclusive Deal
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,221
From (per person) 608
Cruise
 (1)

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 April 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$837
SUITE
-
From (per person) 837
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Departures: Apr 2025 to Nov 2025
Countries Visited: France, Italy, Spain
Early Booking OfferExclusive Deal
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,320
From (per person) 608
Cruise
 (1)

3 Days (2 Nights) Marseille to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2025
Countries Visited: France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$710
BALCONY
$760
SUITE
-
From (per person) 710
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Departure: 16 October 2025
Countries Visited: France, Spain
Early Booking Offer
INSIDE
$608
OCEANVIEW
-
BALCONY
$806
SUITE
$1,320
From (per person) 608
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Departure: 20 April 2025
Countries Visited: Spain, France, Italy
Early Booking Offer
INSIDE
$806
OCEANVIEW
$905
BALCONY
$954
SUITE
$1,469
From (per person) 806
Cruise

2 Days (1 Nights) La Goulette to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 31 July 2025
Countries Visited: Tunisia, Sicily
Exclusive Deal
INSIDE
$326
OCEANVIEW
-
BALCONY
$425
SUITE
-
From (per person) 326
Cruise

5 Days (4 Nights) Valencia to Barcelona
Cruise Line: MSC Cruises
Departure: 13 November 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$776
BALCONY
$924
SUITE
$1,528
From (per person) 776
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Departure: 21 May 2026
Countries Visited: Spain, France
Exclusive Deal
INSIDE
$867
OCEANVIEW
$1,000
BALCONY
$1,031
SUITE
$1,673
Save (per person) 480
From (per person) 867
New ReleaseCruise

5 Days (4 Nights) Nice to Nice
Cruise Line: Scenic
Departure: 21 May 2026
Countries Visited: France, Italy, Monaco
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$7,670
SUITE
$9,155
Save (per person) 2,065
From (per person) 7,670
Cruise

4 Days (3 Nights) Athens to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 30 October 2025
Countries Visited: Greece, Croatia, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$679
BALCONY
$887
SUITE
$1,065
From (per person) 679
Cruise

5 Days (4 Nights) Lisbon to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 14 April 2025
Countries Visited: Portugal, Spain
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$3,188
SUITE
$3,673
From (per person) 3,188
Cruise

4 Days (3 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Departure: 01 October 2025
Countries Visited: Sicily, Malta, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$837
SUITE
$1,293
From (per person) 837
Cruise

4 Days (3 Nights) Rome to Genoa
Cruise Line: MSC Cruises
Departure: 12 December 2025
Countries Visited: Italy, France
Early Booking Offer
INSIDE
$352
OCEANVIEW
$441
BALCONY
$530
SUITE
$976
From (per person) 352
Cruise

4 Days (3 Nights) Rome to Kusadasi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 May 2025
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
$609
OCEANVIEW
$738
BALCONY
$857
SUITE
-
From (per person) 609
Cruise

5 Days (4 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 03 April 2025
Countries Visited: France, Spain, Italy
Exclusive Deal
INSIDE
$588
OCEANVIEW
$736
BALCONY
$1,132
SUITE
$1,360
From (per person) 588
Cruise

4 Days (3 Nights) Cagliari to Marseille
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 31 March 2025
Countries Visited: Sardinia, Italy, France
Exclusive Deal
INSIDE
$471
OCEANVIEW
$580
BALCONY
$877
SUITE
$1,035
From (per person) 471
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Departure: 11 April 2025
Countries Visited: Spain, France
Exclusive Deal
INSIDE
$886
OCEANVIEW
$976
BALCONY
$1,007
SUITE
$2,750
Save (per person) 490
From (per person) 886
Cruise

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 October 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$384
OCEANVIEW
-
BALCONY
$483
SUITE
$789
From (per person) 384
Cruise

5 Days (4 Nights) Barcelona to Valletta
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 18 April 2025
Countries Visited: Spain, Sicily, Malta
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$3,188
SUITE
$3,777
From (per person) 3,188
Results: 1-30 of 50

No Results found. Try changing your search filters.