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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 52 unique cruise itineraries from 3 leading cruise lines. April is the most popular month to join a short cruise break sailing in and around the Mediterranean with 67 departures starting between March 2025 and October 2026.
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52 Cruises (67 Cruise Departures)
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Apr 2025 to Nov 2025
Countries Visited: Spain, France, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$369
OCEANVIEW
$439
BALCONY
$499
SUITE
$819
From (per person) 369
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Magnifica (+2 more), MSC Musica, MSC Opera
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France
One Way Cruise Offer
INSIDE
$79
OCEANVIEW
$119
BALCONY
$159
SUITE
$309
From (per person) 79
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 07 November 2025
Countries Visited: Italy, Spain, France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$332
OCEANVIEW
$402
BALCONY
$482
SUITE
$722
From (per person) 332
View Trip
4 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: Oct 2025 to Oct 2026
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$600
OCEANVIEW
$700
BALCONY
$679
SUITE
$1,463
Save (per person) 456
From (per person) 600
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 21 April 2025
Countries Visited: Italy, France
One Way Cruise Offer
INSIDE
$125
OCEANVIEW
$185
BALCONY
$235
SUITE
$505
From (per person) 125
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 21 April 2025
Countries Visited: Italy, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$293
SUITE
-
From (per person) 293
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Athens to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 30 October 2025
Countries Visited: Greece, Croatia, Italy
One Way Cruise Offer
INSIDE
$269
OCEANVIEW
$349
BALCONY
-
SUITE
-
From (per person) 269
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Marseille to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2025
Countries Visited: France, Italy
One Way Cruise Offer
INSIDE
-
OCEANVIEW
$345
BALCONY
$415
SUITE
-
From (per person) 345
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 20 April 2025
Countries Visited: Spain, France, Italy
Escape To Sea - Cruise Only
INSIDE
$501
OCEANVIEW
-
BALCONY
$641
SUITE
$941
From (per person) 501
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 03 April 2025
Countries Visited: France, Spain, Italy
One Way Cruise Offer
INSIDE
$399
OCEANVIEW
$509
BALCONY
-
SUITE
$879
From (per person) 399
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 07 May 2025
Countries Visited: Spain, Italy
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
$297
BALCONY
$407
SUITE
$728
From (per person) 297
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
One Way Cruise Offer
INSIDE
$211
OCEANVIEW
$251
BALCONY
$351
SUITE
$591
From (per person) 211
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Valencia to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 13 November 2025
Countries Visited: Spain, France, Italy
One Way Cruise Offer
INSIDE
$365
OCEANVIEW
$475
BALCONY
$525
SUITE
$925
From (per person) 365
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Livorno to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 26 October 2025
Countries Visited: Italy, France, Spain
One Way Cruise Offer
INSIDE
$174
OCEANVIEW
$234
BALCONY
$274
SUITE
$464
From (per person) 174
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Olbia to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 November 2025
Countries Visited: Sardinia, Italy, France, Spain
One Way Cruise Offer
INSIDE
$289
OCEANVIEW
$359
BALCONY
-
SUITE
-
From (per person) 289
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 24 April 2025
Countries Visited: Spain, Italy, France
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
-
BALCONY
$586
SUITE
$886
From (per person) 586
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valletta to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 05 November 2025
Countries Visited: Malta, Spain, France, Italy
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$652
SUITE
-
From (per person) 652
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily, Italy
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$1,889
From (per person) 1,889
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Kusadasi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 May 2025
Countries Visited: Italy, Greece, Turkey
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$564
SUITE
-
From (per person) 564
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$618
SUITE
$1,338
From (per person) 618
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 April 2025
Countries Visited: Spain, France, Italy
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$600
SUITE
-
From (per person) 600
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Cagliari to Marseille
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 31 March 2025
Countries Visited: Sardinia, Italy, France
One Way Cruise Offer
INSIDE
-
OCEANVIEW
$349
BALCONY
-
SUITE
$629
From (per person) 349
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Apr 2025 to Apr 2025
Countries Visited: France, Spain, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
-
OCEANVIEW
$550
BALCONY
$620
SUITE
$970
From (per person) 550
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 09 May 2025
Countries Visited: Italy, Spain, France
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$749
SUITE
$929
From (per person) 749
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Valencia
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 06 May 2025
Countries Visited: France, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$489
SUITE
$849
From (per person) 489
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Sinfonia
Departures: May 2025 to May 2026
Countries Visited: Turkey, Greece, Italy
One Way Cruise Offer
INSIDE
$249
OCEANVIEW
$359
BALCONY
$409
SUITE
$1,039
From (per person) 249
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Seaview, MSC Splendida
Departures: Apr 2025 to Apr 2026
Countries Visited: France, Italy, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$389
OCEANVIEW
$469
BALCONY
$519
SUITE
$849
From (per person) 389
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Barcelona to Marseille
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 11 April 2026
Countries Visited: Spain, France
One Way Cruise Offer
INSIDE
$129
OCEANVIEW
$169
BALCONY
$219
SUITE
$479
From (per person) 129
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Seaview, MSC Splendida
Departures: Nov 2025 to Apr 2026
Countries Visited: Italy, Spain, France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$392
OCEANVIEW
$472
BALCONY
$562
SUITE
$852
From (per person) 392
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 06 November 2025
Countries Visited: France, Italy, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$339
OCEANVIEW
$399
BALCONY
$479
SUITE
$719
From (per person) 339
View Trip
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