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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 573 unique cruise itineraries from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 659 departures starting between April 2025 and June 2027.
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573 Cruises (659 Cruise Departures)
9 Day Historical Cities of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 June 2026
Countries Visited: Malta, Sicily, Italy, Greece
INSIDE
-
OCEANVIEW
-
BALCONY
$6,770
SUITE
$12,620
From (per person) 6,770
View Trip
6 Day Grand Prix Weekend Voyage with Azamara Cruises
Cruise
 (1)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 21 May 2026
Countries Visited: Spain, France
INSIDE
$1,429
OCEANVIEW
$1,809
BALCONY
$2,059
SUITE
$2,869
From (per person) 1,429
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: May 2026 to Jun 2026
Countries Visited: France, Italy, Malta, Sicily (+1 more), Corsica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$9,700
BALCONY
$10,800
SUITE
$14,500
From (per person) 9,700
View Trip
12 Day Spain & Italy Cruise: Barcelona, Salerno & Rome with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 February 2027
Countries Visited: Spain, Sardinia, Tunisia, Malta (+2 more), Sicily, Italy
INSIDE
$3,049
OCEANVIEW
$3,549
BALCONY
$4,429
SUITE
$6,589
From (per person) 3,049
View Trip
8 Day A Journey Of Historic Splendour & Stunning Landscapes with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2026
Countries Visited: Monaco, Italy, Sicily, Malta (+1 more), Spain
Upgrade Your Ocean OfferBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$5,240
SUITE
$6,040
From (per person) 5,240
View Trip
9 Day Total Solar Eclipse in the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 06 August 2026
Countries Visited: France, Corsica, Spain
INSIDE
-
OCEANVIEW
-
BALCONY
$8,720
SUITE
$16,400
From (per person) 8,720
View Trip
12 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 09 October 2025
Countries Visited: France, Italy, Sicily, Montenegro
INSIDE
$3,279
OCEANVIEW
$3,499
BALCONY
$3,859
SUITE
$6,849
From (per person) 3,279
View Trip
13 Day Iconic Mediterranean Shores with Oceania Cruises
Cruise

13 Days (12 Nights) Athens to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 24 July 2025
Countries Visited: Greece, Malta, Sicily, Italy (+3 more), Spain, France, Monaco
Exclusive DealSolo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,999
SUITE
$10,699
Save (per person) 5,999
From (per person) 5,999
View Trip
22 Day Discover the Wonders of the Mediterranean with Emerald Cruises
New ReleaseCruise
 (3)

22 Days (21 Nights) Athens to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 17 October 2026
Countries Visited: Greece, Sicily, Malta, Italy (+4 more), Corsica, Spain, Morocco, Portugal
2 for 1 Fare + Fly Free Economy2 for 1 Fare + Fly Free Premium Economy
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$22,860
Save (per person) 23,110
From (per person) 22,860
View Trip
21 Day Tyrrhenian & Mediterranean Overture with Seabourn
Cruise

21 Days (20 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Departures: Nov -0001 to Apr 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+4 more), Corsica, France, Spain, Sardinia
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 0
View Trip
11 Day Mediterranean Cruise: Spain, Italy & Greece with Azamara Cruises
Cruise
 (2)

11 Days (10 Nights) Malaga to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 02 July 2025
Countries Visited: Spain, Tunisia, Malta, Sicily (+1 more), Greece
INSIDE
$3,719
OCEANVIEW
$3,949
BALCONY
-
SUITE
-
From (per person) 3,719
View Trip
15 Day An Extended Journey Of Mediterranean Islands And Artistic Masterpieces with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 September 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+4 more), Monaco, France, Sardinia, Corsica
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$17,620
From (per person) 17,620
View Trip
9 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (3)

9 Days (8 Nights) Nice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 07 July 2025
Countries Visited: France, Italy
Azamara Circle Loyalty Quarterly Savings
INSIDE
$2,459
OCEANVIEW
$2,379
BALCONY
-
SUITE
$5,069
From (per person) 2,379
View Trip
9 Day A Circumnavigation of Sicily - with Smithsonian Journeys with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Jun 2025 to Aug 2026
Countries Visited: Malta, Sicily, Tunisia
INSIDE
-
OCEANVIEW
-
BALCONY
$8,370
SUITE
$14,040
From (per person) 8,370
View Trip
15 Day An Extended Journey Of Golden Coasts And Emerald Islands with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jul 2025 to Aug 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+4 more), France, Monaco, Corsica, Sardinia
Upgrade Your Ocean OfferBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$9,545
SUITE
$13,680
From (per person) 9,545
View Trip
11 Day Italian & Iberian Radiance with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 01 June 2026
Countries Visited: Spain, France, Italy, Portugal
Exclusive Deal
INSIDE
$3,199
OCEANVIEW
$3,549
BALCONY
$5,299
SUITE
$7,299
Save (per person) 3,199
From (per person) 3,199
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 October 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,000
From (per person) 10,000
View Trip
13 Day French & Italian Treasures with Oceania Cruises
Cruise
 (3)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 30 September 2026
Countries Visited: Spain, France, Italy, Corsica (+3 more), Sardinia, Sicily, Malta
Exclusive Deal
INSIDE
$3,599
OCEANVIEW
$3,999
BALCONY
$6,199
SUITE
$8,599
Save (per person) 3,599
From (per person) 3,599
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 24 January 2026
Countries Visited: Spain, Sardinia, Malta, Tunisia (+2 more), Sicily, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$6,900
BALCONY
$7,700
SUITE
$15,700
From (per person) 6,900
View Trip
12 Day Lisbon to Monte Carlo with Silversea
Cruise

12 Days (11 Nights) Lisbon to Monte Carlo
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 24 September 2025
Countries Visited: Portugal, Gibraltar, Spain, Monaco
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$5,950
BALCONY
$7,150
SUITE
$6,850
From (per person) 5,950
View Trip
11 Day Charmed Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 21 April 2026
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Exclusive Deal
INSIDE
$3,199
OCEANVIEW
$3,549
BALCONY
$5,049
SUITE
$6,999
Save (per person) 3,199
From (per person) 3,199
View Trip
8 Day Monte Carlo to Rome with Silversea
Cruise

8 Days (7 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departures: Jul 2026 to Aug 2026
Countries Visited: Monaco, France, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,400
From (per person) 7,400
View Trip
11 Day Best of the Amalfi Coast, Corinth Canal Passage & Greek Isles with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 02 May 2026
Countries Visited: Italy, Sicily, Malta, Greece
2 for 1 Fare + Fly Free Economy2 for 1 Fare + Fly Free Premium Economy
INSIDE
-
OCEANVIEW
$8,135
BALCONY
-
SUITE
$10,885
Save (per person) 8,255
From (per person) 8,135
View Trip
22 Day An Extended Journey To Mediterranean Glamour And Enchanting Coastlines with Explora Journeys
Cruise

22 Days (21 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 26 May 2025
Countries Visited: Monaco, Italy, Sicily, Sardinia (+3 more), Spain, France, Tunisia
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,950
From (per person) 18,950
View Trip
15 Day Lisbon to Civitavecchia with Silversea
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 October 2026
Countries Visited: Portugal, Spain, Gibraltar, Sardinia (+3 more), Tunisia, Sicily, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$7,400
BALCONY
$9,200
SUITE
$13,700
From (per person) 7,400
View Trip
10 Day Ancient Shores of the Mediterranean with Ponant
Cruise
 (1)

10 Days (9 Nights) Athens to Malaga
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 November 2025
Countries Visited: Greece, Italy, Sicily, Tunisia (+2 more), Algeria, Spain
INSIDE
-
OCEANVIEW
-
BALCONY
$6,190
SUITE
$11,510
From (per person) 6,190
View Trip
8 Day Enchanting Italian Coastlines with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: Aug 2025 to Aug 2026
Countries Visited: Italy, Sardinia, Corsica
2 for 1 Fare + Fly Free Economy2 for 1 Fare + Fly Free Premium Economy
INSIDE
-
OCEANVIEW
$5,890
BALCONY
-
SUITE
$7,940
Save (per person) 18,815
From (per person) 5,890
View Trip
8 Day Iberian Peninsula & Sicily with Ponant
Cruise
 (1)

8 Days (7 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 28 April 2026
Countries Visited: Spain, Sicily, Malta
INSIDE
-
OCEANVIEW
-
BALCONY
$5,250
SUITE
$9,730
From (per person) 5,250
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 06 August 2026
Countries Visited: France, Corsica, Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$9,600
BALCONY
$10,400
SUITE
$18,400
From (per person) 9,600
View Trip
8 Day Cruising the Mediterranean: Sicily, Sardinia, and Mallorca - with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Valletta to Tarragona
Cruise Line: Ponant
Ship: L'Austral
Departure: 03 October 2025
Countries Visited: Malta, Sicily, Sardinia, Spain
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
$6,330
BALCONY
$6,800
SUITE
$10,130
From (per person) 6,330
View Trip
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