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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 134 unique cruise itineraries from 10 leading cruise lines. February is the most popular month to join a luxury cruise around South America with 240 departures starting between February 2025 and March 2027.
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83 Days
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134 Cruises (240 Cruise Departures)
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Belem to Belem
Cruise Line: Seabourn
Ship: Seabourn Venture
Departures: Oct 2025 to Oct 2025
Countries Visited: Brazil
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,904
From (per person) 7,904
View Trip
19 Day Valparaiso to Buenos Aires with Silversea
Cruise

19 Days (18 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 15 January 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,100
BALCONY
$12,900
SUITE
$19,300
Save (per person) 1,500
From (per person) 11,100
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$12,000
SUITE
$18,600
Save (per person) 3,000
From (per person) 12,000
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Brazil, Uruguay, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$9,500
BALCONY
$10,200
SUITE
$14,100
From (per person) 9,500
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Countries Visited: Peru, Chile, Argentina
2 for 1 Fares + Fly Free Premium Economy2 for 1 Cruise Fares
INSIDE
-
OCEANVIEW
-
BALCONY
$27,886
SUITE
$34,186
Save (per person) 22,269
From (per person) 27,886
View Trip
12 Day South American Splendor with Regent Seven Seas
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 December 2025
Countries Visited: Brazil, Uruguay, Argentina
Exclusive DealUpgrade Your Horizon
INSIDE
-
OCEANVIEW
-
BALCONY
$7,499
SUITE
$9,020
Save (per person) 12,899
From (per person) 7,499
View Trip
11 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 February 2027
Countries Visited: Brazil, Uruguay, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,400
Save (per person) 1,500
From (per person) 9,400
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departure: 05 December 2026
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$22,500
SUITE
$34,200
From (per person) 22,500
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2025 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Complimentary Hotel Night
From (per person) 14,190
View Trip
23 Day Barbados To Brazil & Buenos Aires Voyage with Azamara Cruises
Cruise
 (1)

23 Days (22 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 17 January 2026
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
INSIDE
$6,749
OCEANVIEW
$6,929
BALCONY
$8,519
SUITE
$13,019
From (per person) 6,749
View Trip
19 Day Buenos Aires to Valparaiso with Silversea
Cruise

19 Days (18 Nights) Buenos Aires to Valparaiso
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 26 February 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,100
BALCONY
$12,400
SUITE
$19,200
Save (per person) 1,500
From (per person) 11,100
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-Port
INSIDE
-
OCEANVIEW
$6,100
BALCONY
$7,400
SUITE
$10,800
From (per person) 6,100
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 02 February 2026
Countries Visited: Argentina, Uruguay, Brazil
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$8,600
BALCONY
$9,900
SUITE
$17,000
Save (per person) 1,500
From (per person) 8,600
View Trip
13 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

13 Days (12 Nights) Belem to Rio de Janeiro
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 30 October 2025
Countries Visited: Brazil
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,689
From (per person) 9,689
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 18 October 2025
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$62,500
From (per person) 62,500
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2025 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Complimentary Hotel Night
From (per person) 16,990
View Trip
26 Day Carnival Rio & Amazon Voyage with Azamara Cruises
Cruise
 (1)

26 Days (25 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 February 2025
Countries Visited: Argentina, Uruguay, Brazil, Trinidad and Tobago (+1 more), Barbados
INSIDE
-
OCEANVIEW
-
BALCONY
$8,259
SUITE
-
From (per person) 8,259
View Trip
17 Day Buenos Aires to Valparaiso with Silversea
Cruise

17 Days (16 Nights) Buenos Aires to Valparaiso
Cruise Line: Silversea
Ship: Silver Nova
Departure: 17 February 2027
Countries Visited: Argentina, Falkland Islands, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,000
Save (per person) 1,500
From (per person) 11,000
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Nov 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$24,500
SUITE
$35,100
From (per person) 24,500
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (1)

24 Days (23 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 January 2027
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
INSIDE
$7,029
OCEANVIEW
$7,779
BALCONY
$9,779
SUITE
$14,419
From (per person) 7,029
View Trip
18 Day Fjords & Glaciers of Southern Chile & Patagonia with Scenic
New ReleaseCruise

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Countries Visited: Argentina, Chile, Uruguay
2 for 1 Fares + Fly Free Premium Economy2 for 1 Fares + Fly Free Business Class
INSIDE
-
OCEANVIEW
-
BALCONY
$14,583
SUITE
$38,583
Save (per person) 14,607
From (per person) 14,583
View Trip
21 Day Rio De Janeiro to Bridgetown with Silversea
Cruise

21 Days (20 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 March 2025
Countries Visited: Brazil, French Guiana, Barbados
Essential FareDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,100
From (per person) 12,100
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2026 to Feb 2027
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$10,600
SUITE
$17,100
Save (per person) 3,000
From (per person) 10,600
View Trip
13 Day Bounty Of Brazil with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 January 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive DealFlash Sale + Prestige Beverage Package
INSIDE
$3,599
OCEANVIEW
$4,399
BALCONY
$3,920
SUITE
$5,520
Save (per person) 3,599
From (per person) 3,599
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
INSIDE
-
OCEANVIEW
$13,730
BALCONY
$14,630
SUITE
$22,310
From (per person) 13,730
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
INSIDE
$4,269
OCEANVIEW
$4,679
BALCONY
$5,929
SUITE
$7,729
From (per person) 4,269
View Trip
12 Day Valparaiso to Puerto Williams with Silversea
Cruise

12 Days (11 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 12 October 2025
Countries Visited: Chile, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,700
From (per person) 12,700
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departure: 21 March 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$13,100
SUITE
$20,200
Save (per person) 1,500
From (per person) 13,100
View Trip
19 Day Cape Horn Encounter with Oceania Cruises
Cruise

19 Days (18 Nights) San Antonio to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$5,299
OCEANVIEW
$6,399
BALCONY
$6,799
SUITE
-
Save (per person) 5,299
From (per person) 5,299
View Trip
11 Day Brazilian Brilliance with Oceania Cruises
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive DealFlash Sale + Prestige Beverage Package
INSIDE
$2,999
OCEANVIEW
$3,599
BALCONY
$3,400
SUITE
$4,845
Save (per person) 2,999
From (per person) 2,999
View Trip
Results: 1-30 of 134

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