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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 138 unique cruise itineraries from 9 leading cruise lines. February is the most popular month to join a luxury cruise around South America with 243 departures starting between January 2025 and March 2027.
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83 Days
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138 Cruises (243 Cruise Departures)
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$18,569
SUITE
$28,614
Save (per person) 327
From (per person) 17,393
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (1)

24 Days (23 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 January 2027
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
INSIDE
$10,145
OCEANVIEW
$11,204
BALCONY
$14,075
SUITE
$20,748
From (per person) 10,145
View Trip
23 Day Barbados To Brazil & Buenos Aires Voyage with Azamara Cruises
Cruise
 (1)

23 Days (22 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 17 January 2026
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
Circle Club Voyage
INSIDE
$11,666
OCEANVIEW
$12,428
BALCONY
$15,279
SUITE
$23,358
From (per person) 11,666
View Trip
26 Day Carnival Rio & Amazon Voyage with Azamara Cruises
Cruise
 (1)

26 Days (25 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 February 2025
Countries Visited: Argentina, Uruguay, Brazil, Trinidad and Tobago (+1 more), Barbados
INSIDE
$6,659
OCEANVIEW
$9,313
BALCONY
$9,550
SUITE
$19,490
From (per person) 6,659
View Trip
11 Day Peru & Chile Voyage with Azamara Cruises
Cruise
 (1)

11 Days (10 Nights) Lima to San Antonio
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 23 January 2025
Countries Visited: Peru, Chile
INSIDE
$2,337
OCEANVIEW
$2,407
BALCONY
$4,129
SUITE
-
From (per person) 2,337
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
Circle Club Voyage
INSIDE
$7,658
OCEANVIEW
$8,390
BALCONY
$10,638
SUITE
$13,875
From (per person) 7,658
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 02 February 2026
Countries Visited: Argentina, Uruguay, Brazil
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,385
BALCONY
$12,969
SUITE
$24,552
Save (per person) 2,615
From (per person) 11,385
View Trip
10 Day Wellness Retreat - Panama City to Valparaiso with Scenic
New ReleaseCruise

10 Days (9 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 26 October 2026
Countries Visited: Panama, Chile
Super EarlybirdReduced Single Supplement
INSIDE
-
OCEANVIEW
-
BALCONY
$8,343
SUITE
$10,778
Save (per person) 3,052
From (per person) 8,343
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$18,793
SUITE
$19,387
Save (per person) 6,967
From (per person) 18,793
View Trip
12 Day Tastes of Discovery Series: Rhythms of the Brazilian Coastline with Chef Luciana Berry with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 11 October 2025
Countries Visited: Brazil, Uruguay, Argentina
Super EarlybirdReduced Single Supplement
INSIDE
-
OCEANVIEW
-
BALCONY
$13,248
SUITE
$15,861
Save (per person) 5,622
From (per person) 13,248
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise

25 Days (24 Nights) Rio de Janeiro to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive DealFlash Sale
INSIDE
$10,321
OCEANVIEW
$11,958
BALCONY
$12,755
SUITE
$18,440
Save (per person) 2,619
From (per person) 10,321
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 14 February 2026
Countries Visited: Brazil, Uruguay, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$9,603
BALCONY
$11,484
SUITE
$22,968
Save (per person) 4,097
From (per person) 9,603
View Trip
23 Day Journey To The Amazon with Regent Seven Seas
Cruise

23 Days (22 Nights) Panama City to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 March 2027
Countries Visited: Panama, Aruba, Trinidad and Tobago, Brazil (+2 more), Grenada, Curacao
Upgrade Your HorizonExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,339
SUITE
$18,150
Save (per person) 7,831
From (per person) 17,339
View Trip
22 Day The Complete Amazon Experience & Coast Of Brazil with Seabourn
Cruise

22 Days (21 Nights) Belem to Rio de Janeiro
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 21 October 2025
Countries Visited: Brazil
Sail Of The Year
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$24,568
From (per person) 24,568
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 18 October 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$19,206
SUITE
$48,906
Save (per person) 2,694
From (per person) 19,206
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$34,452
Save (per person) 2,708
From (per person) 20,592
View Trip
19 Day Buenos Aires to Valparaiso with Silversea
Cruise

19 Days (18 Nights) Buenos Aires to Valparaiso
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 26 February 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$15,642
BALCONY
$17,325
SUITE
$36,828
Save (per person) 2,658
From (per person) 15,642
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Mar 2026 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 21,490
View Trip
11 Day Brazilian Rhythms with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2026
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,034
SUITE
$8,816
Save (per person) 2,046
From (per person) 6,034
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Feb 2025 to Mar 2027
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$18,414
SUITE
$27,621
Save (per person) 2,711
From (per person) 18,414
View Trip
27 Day Treasures of South America: Chilean Fjords to the Iguazu falls - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Chile, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$27,577
SUITE
$30,151
Save (per person) 6,728
From (per person) 27,577
View Trip
21 Day Rio De Janeiro To San Antonio with Cunard
Cruise

21 Days (20 Nights) Rio de Janeiro to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 08 February 2027
Countries Visited: Brazil, Uruguay, Argentina, Chile
Exclusive Deal
INSIDE
$6,936
OCEANVIEW
$10,401
BALCONY
$11,688
SUITE
-
From (per person) 6,936
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$32,558
SUITE
$38,498
Save (per person) 6,787
From (per person) 32,558
View Trip
21 Day Lima to Buenos Aires with Silversea
Cruise

21 Days (20 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Argentina, Chile, Peru
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$22,572
Save (per person) 2,728
From (per person) 22,572
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-Port
INSIDE
-
OCEANVIEW
-
BALCONY
$11,385
SUITE
$16,137
From (per person) 11,385
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 18 October 2025
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$89,100
From (per person) 89,100
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 25,790
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departure: 05 December 2026
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$33,165
SUITE
$49,698
From (per person) 33,165
View Trip
19 Day Cape Horn Encounter with Oceania Cruises
Cruise

19 Days (18 Nights) San Antonio to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$6,626
OCEANVIEW
$7,241
BALCONY
$7,695
SUITE
-
Save (per person) 4,264
From (per person) 6,626
View Trip
13 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

13 Days (12 Nights) Belem to Rio de Janeiro
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 30 October 2025
Countries Visited: Brazil
Sail Of The Year
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,505
From (per person) 14,505
View Trip
Results: 1-30 of 138

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