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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 129 unique cruise itineraries from 9 leading cruise lines. February and January are the most popular months to join a luxury cruise around South America with 245 departures starting between December 2024 and March 2027.
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129 Cruises (245 Cruise Departures)
11 Day Peru & Chile Voyage with Azamara Cruises
Cruise
 (1)

11 Days (10 Nights) Lima to San Antonio
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 23 January 2025
Countries Visited: Peru, Chile
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,525
From (per person) 8,525
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$18,569
SUITE
$28,614
Save (per person) 327
From (per person) 17,393
View Trip
23 Day Barbados To Brazil & Buenos Aires Voyage with Azamara Cruises
Cruise
 (1)

23 Days (22 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 17 January 2026
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
Circle Club Voyage
INSIDE
$10,250
OCEANVIEW
$10,884
BALCONY
$13,349
SUITE
$20,348
From (per person) 10,250
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
Circle Club Voyage
INSIDE
$6,559
OCEANVIEW
$7,182
BALCONY
$9,073
SUITE
$11,796
From (per person) 6,559
View Trip
20 Day San Antonio To Fort Lauderdale with Cunard
Cruise

20 Days (19 Nights) Santiago to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Anne
Departure: 28 February 2027
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Aruba, USA
Experience Like No Other
INSIDE
$6,490
OCEANVIEW
$9,609
BALCONY
$10,797
SUITE
$18,459
From (per person) 6,490
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$16,929
SUITE
$26,334
Save (per person) 2,699
From (per person) 16,929
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise

25 Days (24 Nights) Rio de Janeiro to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Flex FaresExclusive Deal
INSIDE
$9,748
OCEANVIEW
$11,958
BALCONY
$13,462
SUITE
$19,463
Save (per person) 2,582
From (per person) 9,748
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Peru, Chile, Argentina
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$36,594
SUITE
$46,514
Save (per person) 6,816
From (per person) 36,594
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Oct 2025 to Nov 2025
Countries Visited: Chile, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$13,369
BALCONY
$15,074
SUITE
$32,028
Save (per person) 286
From (per person) 13,369
View Trip
15 Day Season Of Samba with Regent Seven Seas
Cruise

15 Days (14 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 03 December 2025
Countries Visited: Barbados, Saint Vincent, Trinidad and Tobago, French Guiana (+1 more), Brazil
Gift Of Travel OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,131
SUITE
$10,371
Save (per person) 11,109
From (per person) 9,131
View Trip
12 Day Tastes of Discovery Series: Rhythms of the Brazilian Coastline with Chef Luciana Berry with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 11 October 2025
Countries Visited: Brazil, Uruguay, Argentina
Super EarlybirdReduced Single Supplement
INSIDE
-
OCEANVIEW
-
BALCONY
$15,515
SUITE
$15,861
Save (per person) 5,645
From (per person) 15,515
View Trip
9 Day Cartagena to Lima with Silversea
Cruise

9 Days (8 Nights) Cartagena to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 December 2024
Countries Visited: Colombia, Panama, Ecuador, Peru
Port-to-Port
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,504
From (per person) 9,504
View Trip
12 Day Nights Of Samba & Tango with Regent Seven Seas
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 22 January 2027
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,185
SUITE
$14,660
Save (per person) 6,605
From (per person) 13,185
View Trip
10 Day Wellness Retreat - Panama City to Valparaiso with Scenic
New ReleaseCruise

10 Days (9 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 26 October 2026
Countries Visited: Panama, Chile
Super EarlybirdReduced Single Supplement
INSIDE
-
OCEANVIEW
-
BALCONY
$8,343
SUITE
$10,778
Save (per person) 3,052
From (per person) 8,343
View Trip
12 Day Valparaiso to Puerto Williams with Silversea
Cruise

12 Days (11 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 12 October 2025
Countries Visited: Chile, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,553
Save (per person) 4,147
From (per person) 14,553
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Brazil, Uruguay, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$8,415
BALCONY
$9,603
SUITE
$16,335
Save (per person) 4,085
From (per person) 8,415
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 05 April 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$22,077
SUITE
$50,193
Save (per person) 2,723
From (per person) 22,077
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 18 October 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,820
SUITE
$26,829
Save (per person) 2,680
From (per person) 17,820
View Trip
21 Day Rio De Janeiro to Bridgetown with Silversea
Cruise

21 Days (20 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 March 2025
Countries Visited: Brazil, French Guiana, Barbados
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,018
From (per person) 18,018
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2025 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 21,350
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 18 October 2025
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$30,888
SUITE
$47,421
From (per person) 30,888
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Single Supplement SpecialExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$18,496
SUITE
$20,120
Save (per person) 7,264
From (per person) 18,496
View Trip
11 Day Brazilian Rhythms with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2026
Countries Visited: Brazil, Uruguay, Argentina
Flex FaresExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,875
SUITE
-
Save (per person) 2,355
From (per person) 5,875
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2026 to Feb 2027
Countries Visited: Galapagos, Ecuador
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$16,830
SUITE
$25,146
Save (per person) 2,696
From (per person) 16,830
View Trip
13 Day Tango & Samba Celebration with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 14 January 2025
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$5,581
OCEANVIEW
$6,482
BALCONY
$7,234
SUITE
$10,244
Save (per person) 2,039
From (per person) 5,581
View Trip
31 Day Rio De Janeiro to Valparaiso with Silversea
Cruise

31 Days (30 Nights) Rio de Janeiro to Valparaiso
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 14 February 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$23,265
BALCONY
$27,324
SUITE
$56,430
From (per person) 23,265
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-Port
INSIDE
-
OCEANVIEW
$9,405
BALCONY
$11,385
SUITE
$16,137
From (per person) 9,405
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortEssential Fare
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$6,732
From (per person) 6,732
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$14,058
BALCONY
$20,592
SUITE
$34,452
Save (per person) 2,642
From (per person) 14,058
View Trip
31 Day Rio De Janeiro to Valparaiso with Silversea
Cruise

31 Days (30 Nights) Rio de Janeiro to Valparaiso
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$27,522
BALCONY
$30,096
SUITE
$46,728
From (per person) 27,522
View Trip
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