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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 36 departures available from eleven of the world's leading cruise lines.
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13 Days
82 Days
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33 Cruises (36 Cruise Departures)
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise
 (2)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 07 April 2025
Countries Visited: USA, Portugal, Spain
Exclusive DealLatest Offer
INSIDE
$1,489
OCEANVIEW
$1,505
BALCONY
$1,537
SUITE
$5,808
Save (per person) 502
From (per person) 1,489
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (7)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Mar 2025 to Feb 2026
Countries Visited: USA, Sint Maarten, Portugal, Spain
Limited Time Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,292
SUITE
$9,103
Save (per person) 867
From (per person) 5,292
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 14 April 2026
Countries Visited: USA, Portugal, Spain, Italy (+1 more), France
Exclusive Solo Offer
INSIDE
$4,426
OCEANVIEW
$4,809
BALCONY
$5,191
SUITE
$6,721
From (per person) 4,426
View Trip
17 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 26 September 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), Gibraltar
INSIDE
$4,172
OCEANVIEW
$4,707
BALCONY
$5,473
SUITE
$6,161
From (per person) 4,172
View Trip
16 Day Spain & Bermuda Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 26 April 2026
Countries Visited: USA, Bahamas, Bermuda, Portugal (+1 more), Spain
Exclusive Deal
INSIDE
$2,177
OCEANVIEW
$2,599
BALCONY
$2,980
SUITE
$3,820
Save (per person) 996
From (per person) 2,177
View Trip
26 Day Sunlit Isles To Iberia with Oceania Cruises
Cruise
 (1)

26 Days (25 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+2 more), Morocco, Gibraltar
Exclusive Deal
INSIDE
$8,824
OCEANVIEW
$9,864
BALCONY
$13,289
SUITE
$18,497
Save (per person) 2,056
From (per person) 8,824
View Trip
26 Day Western Crossing: Madeira, Morocco & Cote d'Azur with Holland America
Cruise
 (2)

26 Days (25 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 19 April 2025
Countries Visited: USA, Portugal, Gibraltar, Spain (+4 more), Morocco, Sardinia, Italy, France
Exclusive Deal
INSIDE
$3,826
OCEANVIEW
$4,123
BALCONY
$5,509
SUITE
$9,073
From (per person) 3,826
View Trip
15 Day Spanish Passage with Princess
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2025 to Mar 2026
Countries Visited: USA, Spain
Exclusive Deal
INSIDE
$1,389
OCEANVIEW
$1,646
BALCONY
$1,795
SUITE
$2,379
From (per person) 1,389
View Trip
15 Day Cultural Crossing With Madeira And Morocco with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Apr 2025 to Apr 2026
Countries Visited: USA, Portugal, Gibraltar, Spain
Exclusive DealHave It All Offer
INSIDE
$1,349
OCEANVIEW
$1,547
BALCONY
$1,844
SUITE
$4,220
From (per person) 1,349
View Trip
15 Day Spanish Passage with Princess
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Majestic Princess
Departure: 18 February 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,200
OCEANVIEW
-
BALCONY
$1,425
SUITE
$2,190
From (per person) 1,200
View Trip
14 Day Bermuda & Portugal Transatlantic with Celebrity Cruises
Cruise
 (1)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 08 March 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive DealBlack Friday Cyber Sale
INSIDE
$1,392
OCEANVIEW
$1,418
BALCONY
$1,476
SUITE
$7,099
Save (per person) 2,596
From (per person) 1,392
View Trip
15 Day Exotic Atlantic Crossing with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 22 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Black Friday Sale
INSIDE
$4,934
OCEANVIEW
$4,934
BALCONY
$5,597
SUITE
-
From (per person) 4,934
View Trip
25 Day Transatlantic Tranquility with Oceania Cruises
Cruise
 (3)

25 Days (24 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 April 2025
Countries Visited: USA, Saint Barthelemy, Virgin Islands, Antigua and Barbuda (+4 more), Saint Kitts and Nevis, Bermuda, Portugal, Spain
Bonus SavingsExclusive Deal
INSIDE
$6,731
OCEANVIEW
$7,177
BALCONY
$9,300
SUITE
-
Save (per person) 4,299
From (per person) 6,731
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Miami to Valencia
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 06 April 2025
Countries Visited: USA, Sint Maarten, Antigua and Barbuda, Barbados (+2 more), Portugal, Spain
Save And Sail Offer
INSIDE
-
OCEANVIEW
$2,332
BALCONY
$2,836
SUITE
$4,417
From (per person) 2,332
View Trip
15 Day Bermuda & Spain Transatlantic with Celebrity Cruises
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Black Friday Cyber SaleExclusive Deal
INSIDE
$1,506
OCEANVIEW
$2,050
BALCONY
$2,972
SUITE
-
Save (per person) 2,705
From (per person) 1,506
View Trip
17 Day A Grand Journey Bridging America, Azore Isles and Catalonia with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
The Exclusive Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,148
SUITE
$10,791
From (per person) 9,148
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 09 April 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), France
INSIDE
$4,169
OCEANVIEW
$4,398
BALCONY
$5,806
SUITE
$6,387
From (per person) 4,169
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 23 April 2026
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,635
OCEANVIEW
$1,757
BALCONY
$2,337
SUITE
$3,672
Save (per person) 865
From (per person) 1,635
View Trip
82 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

82 Days (81 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 29 June 2026
Countries Visited: USA, Canada, Greenland, Iceland (+16 more), Scotland, Ireland, England, Wales, France, Belgium, Holland, Sweden, Denmark, Germany, Lithuania, Finland, Estonia, Norway, Portugal, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$98,536
SUITE
$105,040
Save (per person) 31,264
From (per person) 98,536
View Trip
15 Day Transatlantic to Spain & Morocco with Virgin Voyages
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 26 April 2026
Countries Visited: USA, Spain, Morocco
INSIDE
$1,498
OCEANVIEW
$1,714
BALCONY
$2,148
SUITE
$15,886
From (per person) 1,498
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Gibraltar (+1 more), Spain
Bonus SavingsExclusive Deal
INSIDE
$4,117
OCEANVIEW
$5,180
BALCONY
$5,960
SUITE
$8,368
Save (per person) 2,243
From (per person) 4,117
View Trip
13 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 30 April 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,232
OCEANVIEW
$1,617
BALCONY
$2,232
SUITE
$7,121
Save (per person) 681
From (per person) 1,232
View Trip
17 Day A Grand Journey From Miami To Barcelona with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
The Exclusive Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,405
SUITE
$11,286
From (per person) 9,405
View Trip
15 Day Royal Bermuda & Regal Spain with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 19 March 2025
Countries Visited: USA, Bahamas, Bermuda, Portugal (+1 more), Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,984
SUITE
$13,172
Save (per person) 7,056
From (per person) 11,984
View Trip
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,401
SUITE
$13,024
Save (per person) 7,199
From (per person) 11,401
View Trip
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+3 more), Morocco, Italy, France
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$26,119
SUITE
$30,109
Save (per person) 11,731
From (per person) 26,119
View Trip
21 Day A Grand Journey From Bomba Carib Beaches To Castanets Of Spain with Explora Journeys
Cruise

21 Days (20 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 March 2025
Countries Visited: USA, Puerto Rico, Antigua and Barbuda, Portugal (+1 more), Spain
The Exclusive Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$10,949
SUITE
$12,820
From (per person) 10,949
View Trip
14 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

14 Days (13 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 03 May 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,383
OCEANVIEW
$1,736
BALCONY
$2,901
SUITE
$10,515
Save (per person) 775
From (per person) 1,383
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 11 April 2026
Countries Visited: USA, Portugal, Spain
INSIDE
$3,833
OCEANVIEW
$4,139
BALCONY
$5,361
SUITE
$5,821
From (per person) 3,833
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 06 April 2025
Countries Visited: USA, Sint Maarten, Antigua and Barbuda, Barbados (+5 more), Portugal, Spain, Sicily, Italy, France
Save And Sail Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$6,316
From (per person) 6,316
View Trip
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