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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 41 departures available from eleven of the world's leading cruise lines.
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13 Days
117 Days
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37 Cruises (41 Cruise Departures)
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+3 more), Morocco, Italy, France
Exclusive DealUpgrade Your Horizon
INSIDE
-
OCEANVIEW
-
BALCONY
$17,999
SUITE
$24,999
Save (per person) 29,999
From (per person) 17,999
View Trip
17 Day Transatlantic Repositioning Cruise From New York to Barcelona with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 26 September 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), Gibraltar
INSIDE
$1,655
OCEANVIEW
$2,045
BALCONY
$2,485
SUITE
$2,945
From (per person) 1,655
View Trip
15 Day Cultural Crossing With Madeira And Gibraltar with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Apr 2025 to Apr 2026
Countries Visited: USA, Portugal, Spain
Exclusive Bonus Onboard CreditExclusive Deal
INSIDE
$819
OCEANVIEW
$869
BALCONY
$1,199
SUITE
$2,079
From (per person) 819
View Trip
14 Day Bermuda & Portugal Transatlantic with Celebrity Cruises
Cruise
 (1)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 08 March 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Deal
INSIDE
$1,344
OCEANVIEW
-
BALCONY
-
SUITE
$4,686
Save (per person) 828
From (per person) 1,344
View Trip
15 Day Spanish Passage with Princess
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2025 to Mar 2026
Countries Visited: USA, Spain
Exclusive Deal
INSIDE
$740
OCEANVIEW
$870
BALCONY
$970
SUITE
$1,420
From (per person) 740
View Trip
15 Day Exotic Atlantic Crossing with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 22 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Flash Sale + Prestige Beverage Package
INSIDE
$2,310
OCEANVIEW
$2,520
BALCONY
-
SUITE
-
Save (per person) 4,288
From (per person) 2,310
View Trip
26 Day Sunlit Isles To Iberia with Oceania Cruises
Cruise
 (1)

26 Days (25 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+2 more), Morocco, Gibraltar
Exclusive Deal
INSIDE
$5,899
OCEANVIEW
$6,599
BALCONY
$8,899
SUITE
$12,399
Save (per person) 5,899
From (per person) 5,899
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Gibraltar (+1 more), Spain
Exclusive DealFlash Sale + Prestige Beverage Package
INSIDE
$2,899
OCEANVIEW
$3,649
BALCONY
$3,780
SUITE
$5,899
Save (per person) 2,899
From (per person) 2,899
View Trip
117 Day Grand Cultural Quest with Regent Seven Seas
Cruise

117 Days (116 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 July 2025
Countries Visited: USA, Canada, Greenland, Iceland (+25 more), Faroe Islands, Scotland, Northern Ireland, England, Ireland, Wales, France, Belgium, Holland, Denmark, Germany, Poland, Lithuania, Latvia, Sweden, Norway, Guernsey, Spain, Portugal, Italy, Greece, Turkey, Montenegro, Croatia, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$100,399
SUITE
$103,399
Save (per person) 150,599
From (per person) 100,399
View Trip
15 Day Spanish Passage with Princess
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Majestic Princess
Departure: 18 February 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$701
OCEANVIEW
-
BALCONY
-
SUITE
$5,260
From (per person) 701
View Trip
16 Day Spain & Bermuda Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 26 April 2026
Countries Visited: USA, Bahamas, Bermuda, Portugal (+1 more), Spain
Exclusive DealExclusive Solo Offer
INSIDE
$1,257
OCEANVIEW
$1,517
BALCONY
$1,799
SUITE
$4,305
Save (per person) 508
From (per person) 1,257
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 April 2026
Countries Visited: USA, Virgin Islands, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$1,119
OCEANVIEW
$1,317
BALCONY
$1,634
SUITE
$4,049
From (per person) 1,119
View Trip
84 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

84 Days (83 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 July 2025
Countries Visited: USA, Canada, Greenland, Iceland (+19 more), Faroe Islands, Scotland, Northern Ireland, England, Ireland, Wales, France, Belgium, Holland, Denmark, Germany, Poland, Lithuania, Latvia, Sweden, Norway, Guernsey, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$71,399
SUITE
$73,699
Save (per person) 106,399
From (per person) 71,399
View Trip
15 Day Transatlantic to Spain & Morocco with Virgin Voyages
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 26 April 2026
Countries Visited: USA, Spain, Morocco
Up To USD $300 Bar Tab
INSIDE
$1,106
OCEANVIEW
$1,400
BALCONY
$1,526
SUITE
$5,600
From (per person) 1,106
View Trip
24 Day A Grand Journey From Caribbean Delights To Iberian Spectacle with Explora Journeys
Cruise

24 Days (23 Nights) San Juan to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 April 2026
Countries Visited: Puerto Rico, Antigua and Barbuda, Saint Barthelemy, Dominican Republic (+4 more), USA, Bermuda, Portugal, Spain
Explora Extended Journey SavingEarly Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$9,540
SUITE
$11,295
From (per person) 9,540
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (7)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Operated By: Viking Cruises
Ship: Viking Mars
Departures: Mar 2025 to Jan 2027
Countries Visited: USA, Sint Maarten, Portugal, Spain
INSIDE
-
OCEANVIEW
-
BALCONY
$2,999
SUITE
$5,499
From (per person) 2,999
View Trip
17 Day A Grand Journey Bridging America, Azore Isles and Catalonia with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,300
From (per person) 13,300
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) New York to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 19 April 2026
Countries Visited: USA, Canada, Portugal, Spain (+2 more), Gibraltar, France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$1,261
OCEANVIEW
$1,549
BALCONY
$1,707
SUITE
$4,222
From (per person) 1,261
View Trip
16 Day Transatlantic Repositioning Cruise From Miami to Barcelona with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 11 April 2026
Countries Visited: USA, Portugal, Spain
INSIDE
$1,430
OCEANVIEW
$1,600
BALCONY
$2,400
SUITE
$2,700
From (per person) 1,430
View Trip
21 Day A Grand Journey From Bomba Carib Beaches To Castanets Of Spain with Explora Journeys
Cruise

21 Days (20 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 March 2025
Countries Visited: USA, Puerto Rico, Antigua and Barbuda, Portugal (+1 more), Spain
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,955
SUITE
$8,155
From (per person) 6,955
View Trip
82 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

82 Days (81 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 29 June 2026
Countries Visited: USA, Canada, Greenland, Iceland (+16 more), Scotland, Ireland, England, Wales, France, Belgium, Holland, Sweden, Denmark, Germany, Lithuania, Finland, Estonia, Norway, Portugal, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$68,199
SUITE
$72,599
Save (per person) 102,999
From (per person) 68,199
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 26 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive DealExclusive Solo Offer
INSIDE
$2,271
OCEANVIEW
$2,521
BALCONY
$2,596
SUITE
$6,446
Save (per person) 1,321
From (per person) 2,271
View Trip
16 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 15 March 2026
Countries Visited: USA, Portugal, Spain, Gibraltar
Exclusive DealExclusive Solo Offer
INSIDE
$1,411
OCEANVIEW
$1,681
BALCONY
$1,703
SUITE
$4,039
Save (per person) 619
From (per person) 1,411
View Trip
26 Day A Grand Journey Of Mayan Exploration And Atlantic Adventures with Explora Journeys
Cruise

26 Days (25 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 March 2025
Countries Visited: USA, Guatemala, Honduras, Belize (+5 more), Mexico, Bermuda, Portugal, Colombia, Spain
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$17,910
From (per person) 17,910
View Trip
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive DealUpgrade Your Horizon
INSIDE
-
OCEANVIEW
-
BALCONY
$7,899
SUITE
$11,499
Save (per person) 14,299
From (per person) 7,899
View Trip
16 Day Transatlantic Repositioning Cruise From Miami to Barcelona with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 14 April 2026
Countries Visited: USA, Portugal, Spain, Italy (+1 more), France
INSIDE
$1,886
OCEANVIEW
$2,036
BALCONY
$2,386
SUITE
$3,496
From (per person) 1,886
View Trip
25 Day Transatlantic Tranquility with Oceania Cruises
Cruise
 (3)

25 Days (24 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 April 2025
Countries Visited: USA, Saint Barthelemy, Virgin Islands, Antigua and Barbuda (+4 more), Saint Kitts and Nevis, Bermuda, Portugal, Spain
Exclusive Deal
INSIDE
$5,999
OCEANVIEW
$6,399
BALCONY
-
SUITE
-
Save (per person) 5,999
From (per person) 5,999
View Trip
13 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 30 April 2025
Countries Visited: USA, Portugal, Spain
Exclusive DealExclusive Solo Offer
INSIDE
$1,129
OCEANVIEW
$1,639
BALCONY
$2,092
SUITE
$4,477
Save (per person) 520
From (per person) 1,129
View Trip
17 Day A Grand Journey From Levely Latin Charm & Tropical Delights To Modernist Marvels with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 March 2026
Countries Visited: USA, Puerto Rico, Saint Martin, Spain (+1 more), Gibraltar
Unique Oceans OfferEarly Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$7,515
SUITE
$8,655
From (per person) 7,515
View Trip
16 Day Transatlantic Repositioning Cruise From New York to Barcelona with Norwegian Cruise Line
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 09 April 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), France
INSIDE
$1,568
OCEANVIEW
$1,718
BALCONY
$2,788
SUITE
$2,968
From (per person) 1,568
View Trip
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