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Cruises from Portugal to Italy

Are you looking for a cruise from Portugal to Italy? June is the most popular month to cruise between Portugal and Italy and there are 19 departures available from seven of the world's leading cruise lines.
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9 Days
29 Days
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$17,200pp
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19 Cruises (19 Cruise Departures)
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Departure: 21 December 2026
Countries Visited: Portugal, Spain, France, Italy (+1 more), Corsica
Exclusive Deal
INSIDE
$4,299
OCEANVIEW
$4,699
BALCONY
$7,199
SUITE
$9,999
Save (per person) 4,299
From (per person) 4,299
Cruise
 (1)

12 Days (11 Nights) Lisbon to Rome
Cruise Line: Norwegian Cruise Line
Departure: 26 April 2025
Countries Visited: Portugal, Gibraltar, Spain, France (+1 more), Italy
INSIDE
$1,213
OCEANVIEW
$1,463
BALCONY
$1,663
SUITE
$2,433
From (per person) 1,213
Cruise
 (1)

15 Days (14 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Departure: 11 June 2026
Countries Visited: Portugal, Spain, Italy, Sicily (+3 more), Malta, Montenegro, Croatia
Exclusive Deal
INSIDE
$4,599
OCEANVIEW
$4,999
BALCONY
$7,499
SUITE
$10,299
Save (per person) 4,599
From (per person) 4,599
Cruise

9 Days (8 Nights) Lisbon to Rome
Cruise Line: Seabourn
Departure: 10 May 2025
Countries Visited: Portugal, Gibraltar, Corsica, Italy
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$4,525
SUITE
$7,649
From (per person) 4,525
Cruise
 (3)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Departure: 04 October 2025
Countries Visited: Portugal, Morocco, Spain, France (+1 more), Italy
Your World + Prestige Drinks PackageExclusive Deal
INSIDE
$3,690
OCEANVIEW
$4,050
BALCONY
$6,300
SUITE
$9,399
Save (per person) 4,508
From (per person) 3,690
Cruise
 (1)

18 Days (17 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Departure: 24 July 2026
Countries Visited: Portugal, Spain, Gibraltar, Corsica (+6 more), Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Exclusive Deal
INSIDE
$5,399
OCEANVIEW
$5,899
BALCONY
$8,799
SUITE
$11,999
Save (per person) 5,399
From (per person) 5,399
Cruise
 (1)

13 Days (12 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Departure: 17 October 2025
Countries Visited: Portugal, Spain, Morocco, Tunisia (+4 more), Malta, Greece, Sicily, Italy
Your World + Prestige Drinks PackageExclusive Deal
INSIDE
$3,420
OCEANVIEW
$3,705
BALCONY
$5,795
SUITE
$7,600
Save (per person) 3,778
From (per person) 3,420
Cruise

11 Days (10 Nights) Lisbon to Genoa
Cruise Line: Seabourn
Departure: 10 May 2026
Countries Visited: Portugal, Gibraltar, Spain, France (+1 more), Italy
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
$4,419
BALCONY
$5,269
SUITE
$9,349
From (per person) 4,419
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Departure: 24 July 2026
Countries Visited: Portugal, Spain, Gibraltar, Corsica (+1 more), Italy
Exclusive Deal
INSIDE
$3,299
OCEANVIEW
$3,649
BALCONY
$5,499
SUITE
$7,499
Save (per person) 3,299
From (per person) 3,299
Cruise

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 04 January 2026
Countries Visited: Portugal, Morocco, Spain, France (+1 more), Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$4,900
SUITE
$10,300
Save (per person) 1,500
From (per person) 4,900
Cruise

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Norwegian Cruise Line
Departure: 02 September 2025
Countries Visited: Portugal, Spain, Gibraltar, France (+1 more), Italy
INSIDE
$1,721
OCEANVIEW
$2,501
BALCONY
$4,951
SUITE
$6,531
From (per person) 1,721
Cruise

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 14 June 2026
Countries Visited: Portugal, Spain, France, Monaco (+1 more), Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,700
Save (per person) 3,000
From (per person) 8,700
Cruise
 (2)

12 Days (11 Nights) Lisbon to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 03 June 2026
Countries Visited: Portugal, Spain, Morocco, Malta (+2 more), Sicily, Italy
Exclusive Deal
INSIDE
$2,129
OCEANVIEW
$2,479
BALCONY
$3,079
SUITE
$4,229
From (per person) 2,129
Cruise
 (3)

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Azamara Cruises
Departure: 17 November 2026
Countries Visited: Portugal, Morocco, Spain, Gibraltar (+2 more), France, Italy
INSIDE
$4,659
OCEANVIEW
$4,999
BALCONY
$6,359
SUITE
$9,459
From (per person) 4,659
Cruise

23 Days (22 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 April 2025
Countries Visited: Portugal, Spain, Morocco, Gibraltar (+2 more), France, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$17,200
From (per person) 17,200
Cruise

15 Days (14 Nights) Funchal to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 20 March 2025
Countries Visited: Portugal, Spain, Morocco, Italy (+2 more), Greece, Croatia
Escape To Sea - Cruise Only
INSIDE
$1,622
OCEANVIEW
$2,256
BALCONY
-
SUITE
-
From (per person) 1,622
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 October 2026
Countries Visited: Portugal, Spain, Gibraltar, Sardinia (+3 more), Tunisia, Sicily, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$9,200
SUITE
$13,700
From (per person) 9,200
Cruise

12 Days (11 Nights) Lisbon to Rome
Cruise Line: Norwegian Cruise Line
Departure: 30 March 2025
Countries Visited: Portugal, Gibraltar, Spain, Italy (+1 more), France
INSIDE
$1,065
OCEANVIEW
$1,125
BALCONY
$1,365
SUITE
$1,565
From (per person) 1,065
Cruise

29 Days (28 Nights) Lisbon to Rome
Cruise Line: Seabourn
Departure: 20 June 2026
Countries Visited: Portugal, Morocco, Spain, France (+6 more), Monaco, Italy, Malta, Tunisia, Sardinia, Corsica
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
$13,854
BALCONY
$15,979
SUITE
$26,009
From (per person) 13,854
Results: 19 results

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