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Uruguay Cruises

Are you looking for a cruise to Uruguay? Choose from 72 unique cruise itineraries to Uruguay, departing from Barcelona, Buenos Aires, Itajai, Lima, Montevideo and more. February is the most popular month to cruise to Uruguay and we have over 174 departures available from thirteen of the world's leading cruise lines.
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72 Cruises (174 Cruise Departures)
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 26 December 2026
Visit: Uruguay, Argentina, Brazil
Inside
$1,629
Oceanview
$1,898
Balcony
$2,053
Suite
$2,820
From
US$1,629
Per Person
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 14 February 2026
Visit: Brazil, Uruguay, Argentina
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,100
Balcony
$8,400
Suite
$16,400
From
US$7,100
Save 3,000
Per Person
View Trip
11 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise
 (1)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 February 2027
Visit: Brazil, Uruguay, Argentina
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,600
Suite
$18,200
From
US$10,600
Save 1,500
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil
Your World Inclusions
Exclusive Savings
Inside
$3,387
Oceanview
$3,678
Balcony
$4,988
Suite
$7,267
From
US$3,387
Save 3,511
Per Person
View Trip
9 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

9 Days (8 Nights) Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 18 March 2026
Visit: Argentina, Uruguay, Brazil
Early Booking Savings
Exclusive Savings
From
US$23,109
Save 30,481
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visit: Brazil, Uruguay, Argentina
Inside
$1,119
Oceanview
$1,159
Balcony
$1,239
Suite
$1,709
From
US$1,119
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 16 February 2026
Visit: Uruguay, Argentina, Brazil
Exclusive Savings
Inside
-
Oceanview
$2,049
Balcony
$2,435
Suite
$3,624
From
US$2,049
Save 55
Per Person
View Trip
11 Day South America with MSC Cruises
Cruise
 (2)

11 Days (10 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 December 2025
Visit: Uruguay, Argentina, Brazil
Exclusive Savings
Inside
$3,188
Oceanview
$3,588
Balcony
$3,989
Suite
$5,468
From
US$3,188
Save 91
Per Person
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Visit: Chile, Argentina, Uruguay
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,163
Suite
$15,025
From
US$13,163
Save 19,835
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Preziosa
Departures: Jan 2026 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Inside
$889
Oceanview
$959
Balcony
$1,089
Suite
$1,349
From
US$889
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Mar 2027 to Mar 2028
Visit: Argentina, Uruguay, Brazil
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$7,614
Suite
$11,582
From
US$7,614
Save 15,376
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 17 February 2026
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,952
Oceanview
$2,286
Balcony
$2,468
Suite
$3,424
From
US$1,952
Save 51
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 28 December 2026
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,986
Oceanview
$2,034
Balcony
$2,131
Suite
$2,616
From
US$1,986
Save 53
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 November 2027
Visit: Brazil, Uruguay, Argentina
Black Friday Sale
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,140
Suite
$11,505
From
US$7,140
Save 15,850
Per Person
View Trip
11 Day South America with MSC Cruises
Cruise
 (2)

11 Days (10 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 26 December 2025
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,041
Suite
$5,206
From
US$4,041
Save 118
Per Person
View Trip
17 Day Patagonia & the Chilean Fjords with Scenic
New ReleaseCruise

17 Days (16 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 November 2027
Visit: Argentina, Uruguay, Chile
Black Friday Sale
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,301
Suite
$18,879
From
US$13,301
Save 21,689
Per Person
View Trip
12 Day South American Splendor with Regent Seven Seas
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 December 2025
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$12,663
From
US$12,663
Save 18,135
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Nov 2025 to Mar 2027
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$919
Oceanview
$1,129
Balcony
$1,249
Suite
$1,839
From
US$919
Save 255
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Feb 2027 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Inside
$869
Oceanview
$959
Balcony
$1,069
Suite
-
From
US$869
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (4)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil
Azamara Always Included
Exclusive Savings
Inside
$3,865
Oceanview
$4,592
Balcony
$5,562
Suite
$7,754
From
US$3,865
Save 84
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Itajai to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 08 March 2027
Visit: Brazil, Uruguay, Argentina
Inside
$779
Oceanview
$969
Balcony
$1,069
Suite
-
From
US$779
Per Person
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Ray
Departure: 17 February 2028
Visit: Argentina, Uruguay, Brazil
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,400
Suite
$20,800
From
US$11,400
Save 1,500
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Jan 2026 to Jan 2027
Visit: Uruguay, Argentina, Brazil
Exclusive Savings
Inside
$1,149
Oceanview
$1,469
Balcony
$1,629
Suite
$2,354
From
US$1,149
Save 62
Per Person
View Trip
18 Day Fjords & Glaciers of Southern Chile & Patagonia with Scenic
New ReleaseCruise

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Feb 2027 to Mar 2028
Visit: Argentina, Chile, Uruguay
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$11,881
Suite
$29,296
From
US$11,881
Save 18,306
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Ponant
Ship: L'Austral
Departure: 16 March 2027
Visit: Argentina, Uruguay, Brazil
Inside
-
Oceanview
-
Balcony
$10,290
Suite
$20,370
From
US$10,290
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 05 January 2027
Visit: Argentina, Brazil, Uruguay
Inside
$1,309
Oceanview
$1,559
Balcony
$1,689
Suite
$2,296
From
US$1,309
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Jan 2026 to Feb 2027
Visit: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$1,219
Oceanview
$1,469
Balcony
$1,599
Suite
$2,209
From
US$1,219
Save 57
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Dec 2025 to Mar 2027
Visit: Uruguay, Argentina, Brazil
Exclusive Savings
Inside
$849
Oceanview
$1,129
Balcony
$1,269
Suite
$1,917
From
US$849
Save 65
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 February 2027
Visit: Argentina, Brazil, Uruguay
Inside
$1,209
Oceanview
$1,459
Balcony
$1,589
Suite
$2,199
From
US$1,209
Per Person
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Visit: Brazil, Uruguay, Argentina
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,800
Balcony
$7,300
Suite
$16,900
From
US$5,800
Save 1,500
Per Person
View Trip
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