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MSC Cruises from Genoa

Start your journey from Genoa with 48 unique MSC cruise itineraries to choose from. April is the most popular month to begin your cruise from Genoa and MSC Cruises have 420 trips departing this season.
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2 Days
23 Days
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48 Cruises (420 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Italy, France, Spain, Portugal (+1 more), Sardinia
Escape To Sea - Cruise Only
INSIDE
$1,262
OCEANVIEW
$1,372
BALCONY
$1,702
SUITE
$2,657
From (per person) 1,262
View Trip
9 Day Mediterranean with MSC Cruises
Cruise

9 Days (8 Nights) Genoa to Rome
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 05 May 2025
Countries Visited: Italy, France, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
-
OCEANVIEW
-
BALCONY
$969
SUITE
$1,529
From (per person) 969
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2026 to Oct 2026
Countries Visited: Italy, France, Spain, Sardinia
Escape To Sea - Cruise Only
INSIDE
$726
OCEANVIEW
$826
BALCONY
$1,036
SUITE
$1,716
From (per person) 726
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 06 May 2025
Countries Visited: Italy, Spain, France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$926
OCEANVIEW
-
BALCONY
$1,136
SUITE
$1,566
From (per person) 926
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 17 April 2025
Countries Visited: Italy, Spain
Escape To Sea - Cruise Only
INSIDE
$746
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 746
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 07 November 2025
Countries Visited: Italy, Spain, France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$332
OCEANVIEW
$402
BALCONY
$482
SUITE
$722
From (per person) 332
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Seaview, MSC Splendida
Departures: Apr 2025 to Apr 2026
Countries Visited: Italy, Spain, France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$392
OCEANVIEW
$472
BALCONY
$562
SUITE
$852
From (per person) 392
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 15 December 2025
Countries Visited: Italy, France, Spain
Escape To Sea - Cruise Only
INSIDE
$338
OCEANVIEW
$428
BALCONY
$518
SUITE
$958
From (per person) 338
View Trip
7 Day MSC Grand Voyages with MSC Cruises
Cruise

7 Days (6 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 October 2025
Countries Visited: Italy, France, Spain, Portugal
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
-
BALCONY
$821
SUITE
-
From (per person) 821
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Nov 2025 to Apr 2026
Countries Visited: Italy, Spain, France
Escape To Sea - Cruise Only
INSIDE
$536
OCEANVIEW
$656
BALCONY
$886
SUITE
$1,556
From (per person) 536
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 30 April 2025
Countries Visited: Italy, France, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$1,239
From (per person) 1,239
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France, Spain, Portugal
One Way Cruise Offer
INSIDE
$439
OCEANVIEW
$559
BALCONY
$834
SUITE
$1,179
From (per person) 439
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2025 to Nov 2025
Countries Visited: Italy, France, Spain, Sardinia
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$700
OCEANVIEW
$850
BALCONY
$1,192
SUITE
$1,760
From (per person) 700
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Splendida
Departures: Apr 2025 to May 2025
Countries Visited: Italy, France, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$424
OCEANVIEW
$484
BALCONY
$564
SUITE
$859
From (per person) 424
View Trip
15 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Genoa to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 November 2025
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
-
BALCONY
$1,949
SUITE
-
From (per person) 1,949
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 16 April 2025
Countries Visited: Italy, Sicily, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$584
SUITE
$884
From (per person) 584
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Genoa to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 07 April 2026
Countries Visited: Italy, France, Spain, Portugal (+3 more), Saint Martin, Bahamas, USA
Escape To Sea - Cruise Only
INSIDE
$1,100
OCEANVIEW
$1,268
BALCONY
$1,576
SUITE
-
From (per person) 1,100
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 21 April 2025
Countries Visited: Italy, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$293
SUITE
-
From (per person) 293
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 26 April 2025
Countries Visited: Italy, Sicily, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$659
SUITE
$1,379
From (per person) 659
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 13 April 2025
Countries Visited: Italy, Sicily, Malta, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$673
SUITE
$1,113
From (per person) 673
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: May 2025 to Oct 2026
Countries Visited: Italy, France, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$689
OCEANVIEW
$868
BALCONY
$905
SUITE
$1,421
From (per person) 689
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Mar 2025 to Apr 2026
Countries Visited: Italy, Sicily, Tunisia, Spain (+1 more), France
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$815
OCEANVIEW
$655
BALCONY
$795
SUITE
$1,344
From (per person) 655
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Genoa to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 October 2025
Countries Visited: Italy, France, Spain, Portugal (+5 more), Antigua and Barbuda, Sint Maarten, Puerto Rico, USA, Bahamas
Escape To Sea - Cruise Only
INSIDE
$1,679
OCEANVIEW
$1,969
BALCONY
$2,509
SUITE
-
From (per person) 1,679
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Genoa to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 October 2025
Countries Visited: Italy, France, Spain, Portugal (+4 more), Antigua and Barbuda, Sint Maarten, Puerto Rico, USA
Cruise Only
INSIDE
$1,329
OCEANVIEW
$1,579
BALCONY
$2,049
SUITE
$3,489
From (per person) 1,329
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Genoa to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 April 2025
Countries Visited: Italy, Greece, Turkey
One Way Cruise Offer
INSIDE
-
OCEANVIEW
$676
BALCONY
$836
SUITE
$1,286
From (per person) 676
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2025 to Nov 2026
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$993
OCEANVIEW
$1,233
BALCONY
$1,393
SUITE
$2,033
From (per person) 993
View Trip
10 Day Mediterranean with MSC Cruises
Cruise

10 Days (9 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 05 May 2025
Countries Visited: Italy, France, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
-
OCEANVIEW
-
BALCONY
$1,353
SUITE
$1,993
From (per person) 1,353
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Alicante
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 13 May 2026
Countries Visited: Italy, France, Spain, Portugal
One Way Cruise Offer
INSIDE
$599
OCEANVIEW
$769
BALCONY
-
SUITE
$1,639
From (per person) 599
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Magnifica (+2 more), MSC Musica, MSC Opera
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France
One Way Cruise Offer
INSIDE
$79
OCEANVIEW
$119
BALCONY
$159
SUITE
$309
From (per person) 79
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Mar 2025 to Apr 2026
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$750
OCEANVIEW
$880
BALCONY
$1,050
SUITE
$1,560
From (per person) 750
View Trip
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