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MSC Cruises from Palermo

Start your journey from Palermo with 12 unique MSC cruise itineraries to choose from. September and October are the most popular months to begin your cruise from Palermo and MSC Cruises have 163 trips departing this season.
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Duration
4 Days
24 Days
Price
$300pp
$1,993pp
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12 Cruises (163 Cruise Departures)
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Countries Visited: Sicily, Spain, France, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$890
OCEANVIEW
$1,019
BALCONY
$1,148
SUITE
$1,623
From (per person) 890
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Departure: 17 September 2025
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
-
BALCONY
$1,168
SUITE
$1,624
From (per person) 1,168
Cruise
 (1)

6 Days (5 Nights) Palermo to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2025 to Apr 2025
Countries Visited: Sicily, Tunisia, Spain, France (+1 more), Italy
One Way Cruise Offer
INSIDE
$463
OCEANVIEW
$562
BALCONY
$680
SUITE
-
From (per person) 463
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Departures: Apr 2025 to Oct 2025
Countries Visited: Sicily, Spain, France, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$951
OCEANVIEW
$1,041
BALCONY
$1,110
SUITE
$1,744
From (per person) 951
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Departures: May 2025 to Oct 2026
Countries Visited: Sicily, Italy, France, Spain (+1 more), Tunisia
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$872
OCEANVIEW
$1,080
BALCONY
$1,095
SUITE
$1,541
From (per person) 872
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Departures: Mar 2025 to Mar 2026
Countries Visited: Sicily, Tunisia, Spain, France (+1 more), Italy
Escape To Sea - Cruise Only
INSIDE
$674
OCEANVIEW
$754
BALCONY
$783
SUITE
-
From (per person) 674
Cruise

24 Days (23 Nights) Palermo to New York
Cruise Line: MSC Cruises
Departure: 16 October 2026
Countries Visited: Sicily, Italy, France, Spain (+3 more), Gibraltar, Portugal, USA
Escape To Sea - Cruise Only
INSIDE
$1,842
OCEANVIEW
$2,218
BALCONY
$2,446
SUITE
-
From (per person) 1,842
Cruise

6 Days (5 Nights) Palermo to Genoa
Cruise Line: MSC Cruises
Departure: 10 November 2025
Countries Visited: Sicily, Spain, France, Italy
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$551
SUITE
$1,046
From (per person) 551
Cruise

4 Days (3 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Departure: 01 October 2025
Countries Visited: Sicily, Malta, Spain
One Way Cruise Offer
INSIDE
$316
OCEANVIEW
-
BALCONY
$494
SUITE
$732
From (per person) 316
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Departures: May 2025 to Oct 2026
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Escape To Sea - Cruise Only
INSIDE
$823
OCEANVIEW
$942
BALCONY
$1,026
SUITE
$1,453
From (per person) 823
Cruise

17 Days (16 Nights) Palermo to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 12 November 2025
Countries Visited: Sicily, Spain, Brazil
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
$1,351
BALCONY
-
SUITE
$2,370
From (per person) 1,351
Cruise

24 Days (23 Nights) Palermo to Miami
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 24 October 2025
Countries Visited: Sicily, Italy, France, Spain (+6 more), Morocco, Barbados, Grenada, Saint Martin, Puerto Rico, USA
Escape To Sea - Cruise Only
INSIDE
$1,842
OCEANVIEW
$2,169
BALCONY
$2,594
SUITE
$4,485
From (per person) 1,842
Results: 12 results

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