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Cruises Starting and Ending in Rome

Are you looking for a cruise starting and ending in Rome? September is the most popular month to join a roundtrip cruise from Rome and we have 537 departures available from fourteen of the world's leading cruise lines.
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91 Cruises (537 Cruise Departures)
8 Day Greek Isles Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: May 2025 to Oct 2026
Countries Visited: Italy, Greece, Turkey
March Vacation SaleExclusive Solo Offer
INSIDE
$1,158
OCEANVIEW
$1,455
BALCONY
$1,269
SUITE
$2,219
Save (per person) 1,069
From (per person) 1,158
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: May 2025 to Oct 2026
Countries Visited: Italy, Spain, France
Escape To Sea
INSIDE
$725
OCEANVIEW
$843
BALCONY
$1,112
SUITE
$1,602
From (per person) 725
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 03 June 2025
Countries Visited: Italy, Greece, Malta, Sicily
INSIDE
$1,253
OCEANVIEW
-
BALCONY
$1,530
SUITE
$1,896
From (per person) 1,253
View Trip
12 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 03 July 2025
Countries Visited: Italy, Greece, Malta, Sicily (+1 more), France
INSIDE
$1,372
OCEANVIEW
-
BALCONY
$1,916
SUITE
$2,213
From (per person) 1,372
View Trip
7 Day Western Mediterranean From Rome To Rome with Norwegian Cruise Line
Cruise
 (1)

7 Days (6 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 08 May 2025
Countries Visited: Italy, Spain, France
INSIDE
$620
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 620
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Nov 2025 to Apr 2026
Countries Visited: Italy, Spain, France
Escape To Sea
INSIDE
$485
OCEANVIEW
$553
BALCONY
$702
SUITE
-
From (per person) 485
View Trip
22 Day The Best of the Mediterranean with Princess
Cruise
 (2)

22 Days (21 Nights) Rome to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 16 August 2025
Countries Visited: Italy, Greece, Turkey, Montenegro (+4 more), Sicily, Spain, Gibraltar, France
Exclusive DealSpring Swing Offer
INSIDE
$3,304
OCEANVIEW
$4,126
BALCONY
$5,284
SUITE
$5,729
From (per person) 3,304
View Trip
12 Day Greece, Italy & Turkey Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 29 September 2025
Countries Visited: Italy, Greece, Turkey
Exclusive DealExclusive Solo Offer
INSIDE
$1,663
OCEANVIEW
$2,285
BALCONY
$2,594
SUITE
$11,198
Save (per person) 946
From (per person) 1,663
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2025 to Aug 2025
Countries Visited: Italy, Greece, Malta, Sicily
INSIDE
$1,005
OCEANVIEW
-
BALCONY
$1,381
SUITE
$1,995
From (per person) 1,005
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
Escape To Sea
INSIDE
-
OCEANVIEW
-
BALCONY
$961
SUITE
$1,481
From (per person) 961
View Trip
15 Day Mediterranean, Aegean & Adriatic with Princess
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departures: May 2026 to Oct 2026
Countries Visited: Italy, Greece, Turkey, Croatia (+1 more), Montenegro
Exclusive DealSpring Swing Offer
INSIDE
$2,035
OCEANVIEW
$2,843
BALCONY
$2,675
SUITE
$3,437
From (per person) 2,035
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 14 July 2025
Countries Visited: Italy, Greece, Malta, Sicily
INSIDE
$1,195
OCEANVIEW
-
BALCONY
$1,640
SUITE
$2,135
From (per person) 1,195
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: Oct 2025 to Oct 2026
Countries Visited: Italy, Sicily, Greece
March Vacation SaleExclusive Solo Offer
INSIDE
$1,285
OCEANVIEW
$1,496
BALCONY
$1,559
SUITE
$2,355
Save (per person) 916
From (per person) 1,285
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Countries Visited: Italy, Sicily, Spain, France
Escape To SeaDrinks and Wi-Fi Included
INSIDE
$956
OCEANVIEW
$1,096
BALCONY
$1,226
SUITE
$1,706
From (per person) 956
View Trip
10 Day Sicily, Naples, Cannes & More with Virgin Voyages
Cruise

10 Days (9 Nights) Rome to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 22 August 2026
Countries Visited: Italy, Sicily, Corsica, France
Sail Into Deeper Savings Best Rate
INSIDE
$1,635
OCEANVIEW
$1,905
BALCONY
$2,183
SUITE
$5,265
From (per person) 1,635
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2025 to Nov 2025
Countries Visited: Italy, France, Spain, Sardinia
Escape To Sea
INSIDE
$698
OCEANVIEW
$868
BALCONY
$1,030
SUITE
$1,788
From (per person) 698
View Trip
11 Day Italy, Greece & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 26 June 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+1 more), Sicily
Exclusive DealExclusive Solo Offer
INSIDE
$2,344
OCEANVIEW
$2,581
BALCONY
$3,143
SUITE
$7,720
Save (per person) 1,423
From (per person) 2,344
View Trip
11 Day Greece, Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 10 October 2025
Countries Visited: Italy, Greece, Croatia, Montenegro (+1 more), Sicily
Exclusive Deal
INSIDE
$2,091
OCEANVIEW
$2,788
BALCONY
$3,266
SUITE
$14,378
Save (per person) 1,274
From (per person) 2,091
View Trip
15 Day An Extended Journey Of Golden Coasts And Emerald Islands with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jul 2025 to Aug 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+4 more), France, Monaco, Corsica, Sardinia
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,900
SUITE
$15,120
From (per person) 9,900
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: May 2025 to Oct 2026
Countries Visited: Italy, Spain, France
March Vacation Sale
INSIDE
$1,172
OCEANVIEW
$1,501
BALCONY
$1,614
SUITE
$2,520
Save (per person) 931
From (per person) 1,172
View Trip
8 Day Enchanting Italian Coastlines with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: Aug 2025 to Aug 2026
Countries Visited: Italy, Sardinia, Corsica
2 for 1 Fare + Fly Free Economy2 for 1 Fare + Fly Free Premium Economy
INSIDE
-
OCEANVIEW
$5,890
BALCONY
-
SUITE
$7,940
Save (per person) 18,815
From (per person) 5,890
View Trip
15 Day Italy And The Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2025 to Jul 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+1 more), Malta
Exclusive Deal
INSIDE
$1,999
OCEANVIEW
$2,269
BALCONY
$2,624
SUITE
$5,394
From (per person) 1,999
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: May 2025 to Oct 2026
Countries Visited: Italy, Greece, Turkey
Mutiple Deals Available
INSIDE
$601
OCEANVIEW
$771
BALCONY
$877
SUITE
$1,587
From (per person) 601
View Trip
11 Day Greece, Turkey & Italy Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 12 October 2025
Countries Visited: Italy, Greece, Turkey
March Vacation Sale
INSIDE
$2,326
OCEANVIEW
$2,425
BALCONY
$2,437
SUITE
-
Save (per person) 1,040
From (per person) 2,326
View Trip
12 Day Greece, Turkey & Italy Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Jul 2026 to Sep 2026
Countries Visited: Italy, Greece, Turkey
Exclusive DealExclusive Solo Offer
INSIDE
$2,424
OCEANVIEW
$2,565
BALCONY
$3,305
SUITE
$6,994
Save (per person) 1,457
From (per person) 2,424
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jul 2025 to Aug 2025
Countries Visited: Italy, Greece, Malta, Sicily
INSIDE
$1,235
OCEANVIEW
-
BALCONY
$1,705
SUITE
$2,490
From (per person) 1,233
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 24 May 2025
Countries Visited: Italy, Greece, Malta, Sicily (+1 more), France
INSIDE
$907
OCEANVIEW
-
BALCONY
$1,155
SUITE
$1,699
From (per person) 907
View Trip
8 Day Mediterranean & Adriatic with Princess
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: Princess
Ships: Enchanted Princess, Sapphire Princess
Departures: Mar 2026 to Nov 2026
Countries Visited: Italy, Greece, Croatia, Montenegro
Exclusive DealSpring Swing Offer
INSIDE
$964
OCEANVIEW
$1,022
BALCONY
$1,361
SUITE
$1,529
From (per person) 964
View Trip
15 Day An Extended Journey Of Mediterranean Islands And Artistic Masterpieces with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 September 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+4 more), Monaco, France, Sardinia, Corsica
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,495
SUITE
$10,845
From (per person) 9,495
View Trip
18 Day Mediterranean & Egypt Cruise: Italy, Greece & Malta with Azamara Cruises
Cruise
 (3)

18 Days (17 Nights) Rome to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 December 2026
Countries Visited: Italy, Sicily, Greece, Egypt (+1 more), Malta
INSIDE
$4,109
OCEANVIEW
$4,689
BALCONY
$5,969
SUITE
$9,249
From (per person) 4,109
View Trip
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