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Cruises From San Diego

Choose from 87 unique cruises starting in San Diego, and traveling to Fort Lauderdale, Miami, New York, Panama City, Sydney and more. October and January are the most popular months to join a cruise from San Diego and you can select from 182 departures available from six leading cruise lines.
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87 Cruises (182 Cruise Departures)
25 Day Mexico Riviera & Circle Hawaii with Holland America
Cruise
 (2)

25 Days (24 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 02 January 2027
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$3,097
OCEANVIEW
$4,087
BALCONY
$4,582
SUITE
$6,463
From (per person) 3,097
View Trip
36 Day Legendary Hawaii, Tahiti & Marquesas with Holland America
Cruise
 (3)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 15 October 2026
Countries Visited: USA, Kiribati, French Polynesia
Exclusive Deal
INSIDE
$4,370
OCEANVIEW
$5,162
BALCONY
$10,310
SUITE
$19,403
From (per person) 4,370
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Oct 2026 to Dec 2026
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$1,362
OCEANVIEW
$1,709
BALCONY
$2,006
SUITE
$2,600
From (per person) 1,362
View Trip
19 Day Circle Hawaii with Holland America
Cruise
 (2)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 26 January 2027
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$2,345
OCEANVIEW
$3,087
BALCONY
$3,533
SUITE
$4,869
From (per person) 2,345
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Countries Visited: USA, Mexico
Latest Offer
INSIDE
$709
OCEANVIEW
$916
BALCONY
$1,026
SUITE
$2,194
Save (per person) 364
From (per person) 709
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Countries Visited: USA, Mexico
Latest Offer
INSIDE
$724
OCEANVIEW
$902
BALCONY
$1,102
SUITE
$1,701
Save (per person) 370
From (per person) 724
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Countries Visited: USA, Mexico
Latest Offer
INSIDE
$415
OCEANVIEW
$511
BALCONY
$592
SUITE
$702
Save (per person) 206
From (per person) 415
View Trip
19 Day Baja Peninsula, Mexican Riviera & Pacific Coast with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 April 2026
Countries Visited: USA, Mexico, Canada
Exclusive Deal
INSIDE
$1,992
OCEANVIEW
$2,220
BALCONY
$4,576
SUITE
$8,318
From (per person) 1,992
View Trip
8 Day Wine Country & Pacific Northwest with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Zaandam
Departure: 17 April 2027
Countries Visited: USA, Canada
Exclusive Deal
INSIDE
$1,133
OCEANVIEW
$1,282
BALCONY
$2,569
SUITE
$3,955
From (per person) 1,133
View Trip
8 Day Baja Peninsula & Sea Of Cortez with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Nieuw Amsterdam (+2 more), Zaandam, Zuiderdam
Departures: Oct 2025 to Mar 2027
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$747
OCEANVIEW
$796
BALCONY
$1,093
SUITE
$1,811
From (per person) 747
View Trip
17 Day Panama Canal with Holland America
Cruise
 (1)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 02 October 2026
Countries Visited: USA, Mexico, Guatemala, El Salvador (+3 more), Panama, Colombia, Bahamas
Exclusive Deal
INSIDE
$2,631
OCEANVIEW
$3,027
BALCONY
$4,017
SUITE
$6,393
From (per person) 2,631
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Mar 2027
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$896
OCEANVIEW
$995
BALCONY
$1,560
SUITE
$2,173
From (per person) 896
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Countries Visited: USA, Mexico
Latest Offer
INSIDE
$502
OCEANVIEW
$601
BALCONY
$670
SUITE
$818
Save (per person) 218
From (per person) 502
View Trip
27 Day Panama Canal & Eastern Caribbean with Holland America
Cruise

27 Days (26 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 27 February 2026
Countries Visited: USA, Mexico, Guatemala, Panama (+8 more), Colombia, Bahamas, Saint Martin, Antigua and Barbuda, Martinique, Dominica, Saint Kitts and Nevis, Virgin Islands
Exclusive Deal
INSIDE
$3,181
OCEANVIEW
$3,468
BALCONY
$4,784
SUITE
$7,042
From (per person) 3,181
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (1)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 09 December 2025
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$996
OCEANVIEW
$1,145
BALCONY
$1,491
SUITE
$3,075
From (per person) 996
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (1)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 04 October 2025
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$746
OCEANVIEW
$845
BALCONY
$1,142
SUITE
$1,984
From (per person) 746
View Trip
17 Day Panama Canal Cruise with Royal Caribbean
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Radiance of the Seas
Departure: 04 October 2025
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+3 more), Panama, Colombia, Cayman Islands
Latest Offer
INSIDE
$2,661
OCEANVIEW
-
BALCONY
-
SUITE
-
Save (per person) 1,047
From (per person) 2,661
View Trip
15 Day Mexican Riviera & Classic California Coast with Holland America
Cruise
 (2)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 01 November 2025
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$1,312
OCEANVIEW
$1,441
BALCONY
$1,906
SUITE
$3,668
From (per person) 1,312
View Trip
18 Day Circle Hawaii Holiday with Holland America
Cruise
 (3)

18 Days (17 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 December 2025
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$1,879
OCEANVIEW
$1,978
BALCONY
$4,305
SUITE
$9,849
From (per person) 1,879
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Aruba
Exclusive DealSpring Swing Offer
INSIDE
$1,445
OCEANVIEW
$1,603
BALCONY
$2,620
SUITE
$3,831
From (per person) 1,445
View Trip
15 Day Mexican Riviera And Classic California Coast with Holland America
Cruise
 (1)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 04 October 2025
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$1,307
OCEANVIEW
$1,476
BALCONY
$1,941
SUITE
$3,753
From (per person) 1,307
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departure: 08 October 2026
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Aruba
Exclusive Deal
INSIDE
$2,565
OCEANVIEW
$2,961
BALCONY
$3,951
SUITE
$6,327
From (per person) 2,565
View Trip
14 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

14 Days (13 Nights) San Diego to Miami
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 19 September 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Colombia
Latest OfferExclusive Solo Offer
INSIDE
$1,522
OCEANVIEW
$1,986
BALCONY
-
SUITE
-
Save (per person) 565
From (per person) 1,522
View Trip
13 Day Historical Baja Peninsula with Holland America
Cruise

13 Days (12 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 15 February 2026
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$1,591
OCEANVIEW
$1,789
BALCONY
$2,482
SUITE
$4,066
From (per person) 1,591
View Trip
12 Day Mexican Riviera & Pacific Coast with Holland America
Cruise
 (3)

12 Days (11 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Zaandam
Departure: 25 April 2026
Countries Visited: USA, Mexico, Canada
Exclusive Deal
INSIDE
$1,195
OCEANVIEW
$1,343
BALCONY
$2,878
SUITE
$5,452
From (per person) 1,195
View Trip
5 Day Pacific Coastal Cruise with Holland America
Cruise
 (1)

5 Days (4 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Eurodam, Zaandam
Departures: Apr 2026 to May 2026
Countries Visited: USA, Canada
Exclusive Deal
INSIDE
$299
OCEANVIEW
$398
BALCONY
$645
SUITE
$1,031
From (per person) 299
View Trip
30 Day Historical Baja Peninsula & Circle Hawaii Holiday with Holland America
Cruise
 (3)

30 Days (29 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 06 December 2025
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$2,718
OCEANVIEW
$2,906
BALCONY
$6,124
SUITE
-
From (per person) 2,718
View Trip
8 Day Mexican Riviera From San Diego To San Diego with Norwegian Cruise Line
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departures: Mar 2026 to Apr 2026
Countries Visited: USA, Mexico
INSIDE
$895
OCEANVIEW
$994
BALCONY
$1,508
SUITE
$1,687
From (per person) 895
View Trip
29 Day Panama Canal & Eastern Caribbean with Holland America
Cruise
 (2)

29 Days (28 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Koningsdam
Departure: 01 November 2025
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+9 more), Panama, Aruba, Bahamas, Saint Martin, Antigua and Barbuda, Saint Lucia, Dominica, Saint Kitts and Nevis, Virgin Islands
Exclusive Deal
INSIDE
$2,785
OCEANVIEW
$3,488
BALCONY
$4,190
SUITE
$6,309
From (per person) 2,785
View Trip
29 Day Mexico Riviera, Pacific Coastal & Circle Hawaii with Holland America
Cruise
 (2)

29 Days (28 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 27 March 2027
Countries Visited: USA, Mexico, Canada
Exclusive Deal
INSIDE
$3,776
OCEANVIEW
$4,964
BALCONY
$5,558
SUITE
$7,439
From (per person) 3,776
View Trip
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Departure Months

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Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Los Angeles Miami New York Orlando Philadelphia San Diego San Francisco Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Lisbon to Miami London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Fort Lauderdale Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to New York New York to Montreal New York to New York New York to Quebec City New York to London Orlando to Orlando Panama City to Miami Quebec City to Boston Rome to Miami Rome to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Miami Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA France to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to New Zealand USA to Argentina USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Spain

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