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MSC Opera

MSC Opera Cruises

Choose from 247 cruise vacations onboard the MSC Opera. Compare cruises ranging from 2 days to 29 days with departures available from March 2025 through to September 2026. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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2 Days
29 Days
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$2,668pp
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36 Cruises (247 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Italy, France, Spain, Portugal (+1 more), Sardinia
Escape To Sea - Cruise Only
INSIDE
$1,262
OCEANVIEW
$1,372
BALCONY
$1,702
SUITE
$2,657
From (per person) 1,262
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Rome to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 March 2025
Countries Visited: Italy, Greece, Croatia
One Way Cruise Offer
INSIDE
-
OCEANVIEW
$599
BALCONY
-
SUITE
-
From (per person) 599
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 17 August 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Escape To Sea - Cruise Only
INSIDE
$1,205
OCEANVIEW
$1,385
BALCONY
-
SUITE
-
From (per person) 1,205
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Spain, Sardinia, Italy, France (+1 more), Portugal
Escape To Sea - Cruise Only
INSIDE
$1,206
OCEANVIEW
$1,346
BALCONY
-
SUITE
$2,645
From (per person) 1,206
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Madeira to Valencia
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 20 March 2025
Countries Visited: Portugal, Spain, Morocco
Escape To Sea - Cruise Only
INSIDE
$721
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 721
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Escape To Sea - Cruise Only
INSIDE
$723
OCEANVIEW
$982
BALCONY
-
SUITE
$1,744
From (per person) 723
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: France, Spain, Portugal, Sardinia (+1 more), Italy
Escape To Sea - Cruise Only
INSIDE
$1,236
OCEANVIEW
$1,356
BALCONY
$1,729
SUITE
$2,642
From (per person) 1,236
View Trip
4 Day South Africa with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Durban to Cape Town
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Mar 2025 to Mar 2026
Countries Visited: South Africa
Escape To Sea - Cruise Only
INSIDE
$298
OCEANVIEW
$348
BALCONY
$474
SUITE
$578
From (per person) 298
View Trip
5 Day South Africa with MSC Cruises
Cruise

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2026 to Mar 2026
Countries Visited: South Africa, Mozambique
Escape To Sea - Cruise Only
INSIDE
$392
OCEANVIEW
$452
BALCONY
-
SUITE
$712
From (per person) 392
View Trip
29 Day MSC Grand Voyages with MSC Cruises
Cruise

29 Days (28 Nights) Bari to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 October 2025
Countries Visited: Italy, Croatia, Greece, Egypt (+6 more), Jordan, Seychelles, Madagascar, Mauritius, Reunion, South Africa
Escape To Sea - Cruise Only
INSIDE
$1,920
OCEANVIEW
$2,400
BALCONY
-
SUITE
$5,510
From (per person) 1,920
View Trip
3 Day Cruising the Adriatic with MSC Cruises
Cruise

3 Days (2 Nights) Bari to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 October 2025
Countries Visited: Italy, Croatia
One Way Cruise Offer
INSIDE
$139
OCEANVIEW
$219
BALCONY
-
SUITE
-
From (per person) 139
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 14 September 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Escape To Sea - Cruise Only
INSIDE
$949
OCEANVIEW
$1,129
BALCONY
-
SUITE
$2,039
From (per person) 949
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: May 2025 to Jun 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Escape To Sea - Cruise Only
INSIDE
$816
OCEANVIEW
$996
BALCONY
-
SUITE
$1,938
From (per person) 816
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Spain, Portugal, Sardinia, Italy (+1 more), France
Escape To Sea - Cruise Only
INSIDE
$1,241
OCEANVIEW
$1,351
BALCONY
-
SUITE
$2,647
From (per person) 1,241
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France, Spain, Portugal
One Way Cruise Offer
INSIDE
$439
OCEANVIEW
$559
BALCONY
$834
SUITE
$1,179
From (per person) 439
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: May 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Escape To Sea - Cruise Only
INSIDE
$861
OCEANVIEW
$1,031
BALCONY
-
SUITE
$1,921
From (per person) 861
View Trip
5 Day South Africa with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Mar 2025 to Mar 2026
Countries Visited: South Africa, Mozambique
Escape To Sea - Cruise Only
INSIDE
$392
OCEANVIEW
$452
BALCONY
$589
SUITE
$712
From (per person) 392
View Trip
4 Day South Africa with MSC Cruises
Cruise

4 Days (3 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2025 to Mar 2026
Countries Visited: South Africa, Mozambique
Escape To Sea - Cruise Only
INSIDE
$318
OCEANVIEW
$368
BALCONY
-
SUITE
$598
From (per person) 318
View Trip
3 Day South Africa with MSC Cruises
Cruise

3 Days (2 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 10 January 2026
Countries Visited: South Africa
Escape To Sea - Cruise Only
INSIDE
$235
OCEANVIEW
$285
BALCONY
-
SUITE
$475
From (per person) 235
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: May 2025 to Sep 2026
Countries Visited: Portugal, Spain, Sardinia, Italy (+1 more), France
Escape To Sea - Cruise Only
INSIDE
$1,181
OCEANVIEW
$1,301
BALCONY
$1,631
SUITE
$2,591
From (per person) 1,181
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: May 2025 to Jun 2025
Countries Visited: Italy, Greece, Croatia, Montenegro
Escape To Sea - Cruise Only
INSIDE
$842
OCEANVIEW
$1,022
BALCONY
-
SUITE
-
From (per person) 842
View Trip
27 Day MSC Grand Voyages with MSC Cruises
Cruise

27 Days (26 Nights) Venice to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2025
Countries Visited: Italy, Croatia, Greece, Egypt (+6 more), Jordan, Seychelles, Madagascar, Mauritius, Reunion, South Africa
Escape To Sea - Cruise Only
INSIDE
$1,879
OCEANVIEW
$2,309
BALCONY
-
SUITE
$5,199
From (per person) 1,879
View Trip
15 Day Canary Islands And Madeira with MSC Cruises
Cruise

15 Days (14 Nights) Funchal to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 20 March 2025
Countries Visited: Portugal, Spain, Morocco, Italy (+2 more), Greece, Croatia
Escape To Sea - Cruise Only
INSIDE
$1,638
OCEANVIEW
$2,278
BALCONY
-
SUITE
-
From (per person) 1,638
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Magnifica (+2 more), MSC Musica, MSC Opera
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France
One Way Cruise Offer
INSIDE
$79
OCEANVIEW
$119
BALCONY
$159
SUITE
$309
From (per person) 79
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Cape Town to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 14 April 2026
Countries Visited: South Africa
Escape To Sea - Cruise Only
INSIDE
$298
OCEANVIEW
$348
BALCONY
-
SUITE
$578
From (per person) 298
View Trip
15 Day South Africa with MSC Cruises
Cruise

15 Days (14 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 27 December 2025
Countries Visited: South Africa, Madagascar, Mauritius, Reunion
Escape To Sea - Cruise Only
INSIDE
$1,761
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 1,761
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: May 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Escape To Sea - Cruise Only
INSIDE
$867
OCEANVIEW
$1,037
BALCONY
-
SUITE
$1,947
From (per person) 867
View Trip
6 Day South Africa with MSC Cruises
Cruise

6 Days (5 Nights) Cape Town to Cape Town
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2026 to Apr 2026
Countries Visited: South Africa, Namibia
Escape To Sea - Cruise Only
INSIDE
$574
OCEANVIEW
$634
BALCONY
-
SUITE
$924
From (per person) 574
View Trip
7 Day Canary Islands And Madeira with MSC Cruises
Cruise

7 Days (6 Nights) Santa Cruz De Tenerife to Rome
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Italy
One Way Cruise Offer
INSIDE
$559
OCEANVIEW
$699
BALCONY
-
SUITE
$1,439
From (per person) 559
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Escape To Sea - Cruise Only
INSIDE
$807
OCEANVIEW
$977
BALCONY
-
SUITE
$1,960
From (per person) 807
View Trip
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