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Cruises From Santa Cruz de Tenerife

Choose from 55 unique cruises starting in Santa Cruz de Tenerife, and travelling to Barcelona, Bari, Dakar, Lisbon, Malaga and more. December is the most popular month to join a cruise from Santa Cruz de Tenerife and you can select from 213 departures available from seven leading cruise lines.
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55 Cruises (213 Cruise Departures)
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santa Cruz De Tenerife to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Nov 2025 to Apr 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,128
OCEANVIEW
$1,277
BALCONY
$1,613
SUITE
$2,593
From (per person) 1,128
View Trip
9 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santa Cruz De Tenerife to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 12 April 2026
Countries Visited: Spain, Morocco, Italy
Exclusive Deal
INSIDE
$1,434
OCEANVIEW
$1,602
BALCONY
$1,988
SUITE
-
From (per person) 1,434
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santa Cruz De Tenerife to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 07 December 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,128
OCEANVIEW
$1,277
BALCONY
$1,613
SUITE
$2,593
From (per person) 1,128
View Trip
11 Day Highlights of Spain, Morocco & Italy with Emerald Cruises
Cruise
 (3)

11 Days (10 Nights) Santa Cruz de Tenerife to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 08 April 2026
Countries Visited: Spain, Morocco, Corsica, Italy
Super Earlybird
INSIDE
-
OCEANVIEW
$10,205
BALCONY
-
SUITE
$14,165
Save (per person) 2,590
From (per person) 10,205
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santa Cruz De Tenerife to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 04 January 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,128
OCEANVIEW
$1,277
BALCONY
$1,613
SUITE
$2,593
From (per person) 1,128
View Trip
11 Day Volcanic Landscapes from Canary Islands to Cape Verde with Ponant
Cruise
 (2)

11 Days (10 Nights) Santa Cruz De Tenerife to Dakar
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 29 December 2025
Countries Visited: Spain, Cape Verde, Senegal
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,502
SUITE
$12,823
Save (per person) 158
From (per person) 8,502
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,112
OCEANVIEW
$3,983
BALCONY
$4,931
SUITE
$11,268
From (per person) 3,112
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Feb 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,696
OCEANVIEW
$1,904
BALCONY
$2,704
SUITE
$4,535
From (per person) 1,696
View Trip
27 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

27 Days (26 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+3 more), Malta, France, Croatia
Latest Offer
INSIDE
$5,106
OCEANVIEW
$5,836
BALCONY
$7,489
SUITE
-
From (per person) 5,106
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Feb 2025 to Oct 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,189
OCEANVIEW
$1,457
BALCONY
$1,545
SUITE
-
From (per person) 1,189
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,696
OCEANVIEW
$1,904
BALCONY
$2,634
SUITE
$4,604
From (per person) 1,696
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,646
OCEANVIEW
$1,904
BALCONY
$2,585
SUITE
$4,159
From (per person) 1,646
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,805
OCEANVIEW
$4,032
BALCONY
$5,278
SUITE
-
From (per person) 3,805
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 12 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,112
OCEANVIEW
$3,983
BALCONY
$4,931
SUITE
$7,704
From (per person) 3,112
View Trip
6 Day A Journey Of Volcanic Isles with Explora Journeys
Cruise

6 Days (5 Nights) Santa Cruz De Tenerife to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2025
Countries Visited: Spain, Gibraltar
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$3,148
SUITE
$3,712
From (per person) 3,148
View Trip
11 Day Canary Islands & Spanish coast with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Santa Cruz de Tenerife to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco
Super Earlybird
INSIDE
-
OCEANVIEW
$10,255
BALCONY
-
SUITE
$14,215
Save (per person) 2,590
From (per person) 10,255
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Feb 2025 to Oct 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,033
OCEANVIEW
$2,310
BALCONY
$2,932
SUITE
-
From (per person) 2,033
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Feb 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$665
OCEANVIEW
$932
BALCONY
$1,426
SUITE
$2,079
From (per person) 665
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 25 October 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,221
OCEANVIEW
$2,696
BALCONY
$3,674
SUITE
-
From (per person) 2,221
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$665
OCEANVIEW
$932
BALCONY
$1,426
SUITE
$2,060
From (per person) 665
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz De Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Italy, Greece
Save And Sail Offer
INSIDE
$1,798
OCEANVIEW
$2,372
BALCONY
$4,016
SUITE
$5,213
From (per person) 1,798
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 15 February 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,083
OCEANVIEW
-
BALCONY
$2,962
SUITE
-
From (per person) 2,083
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 14 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
Latest Offer
INSIDE
$2,292
OCEANVIEW
$3,083
BALCONY
$3,765
SUITE
-
From (per person) 2,292
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 31 October 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,023
OCEANVIEW
$2,478
BALCONY
$3,426
SUITE
$7,872
From (per person) 2,023
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$645
OCEANVIEW
$932
BALCONY
$1,426
SUITE
$2,079
From (per person) 645
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 14 February 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,004
OCEANVIEW
$2,389
BALCONY
$3,130
SUITE
-
From (per person) 2,004
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,754
OCEANVIEW
$1,922
BALCONY
$2,644
SUITE
-
From (per person) 1,754
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+2 more), Malta, France
Latest Offer
INSIDE
$3,757
OCEANVIEW
$4,657
BALCONY
$5,785
SUITE
$10,151
From (per person) 3,757
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,754
OCEANVIEW
$2,001
BALCONY
$2,644
SUITE
$4,218
From (per person) 1,754
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,754
OCEANVIEW
$2,120
BALCONY
$2,693
SUITE
$4,317
From (per person) 1,754
View Trip
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