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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? June and July are the most popular months to cruise between Rome and Barcelona and there are 199 departures available from fifteen of the world's leading cruise lines.
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96 Cruises (199 Cruise Departures)
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Barcelona
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jul 2025 to Sep 2027
Countries Visited: Italy, Monaco, France, Spain
INSIDE
-
OCEANVIEW
-
BALCONY
$2,799
SUITE
$5,049
From (per person) 2,799
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 August 2025
Countries Visited: Italy, France, Sardinia, Sicily (+2 more), Corsica, Spain
Exclusive Deal
INSIDE
$2,089
OCEANVIEW
$2,119
BALCONY
$2,359
SUITE
$5,269
From (per person) 2,089
View Trip
8 Day Mediterranean Holiday Cruise: Barcelona, Palma & Florence with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Countries Visited: Italy, Spain
INSIDE
$1,639
OCEANVIEW
$1,899
BALCONY
$2,459
SUITE
$3,899
From (per person) 1,639
View Trip
8 Day Rome To Barcelona with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$1,109
OCEANVIEW
$1,139
BALCONY
$1,229
SUITE
$3,049
From (per person) 1,109
View Trip
10 Day Rome to Barcelona with Silversea
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,300
Save (per person) 3,000
From (per person) 7,300
View Trip
9 Day Rome to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 10 November 2025
Countries Visited: Italy, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$6,900
BALCONY
$7,700
SUITE
$7,500
From (per person) 6,900
View Trip
11 Day Mediterranean Melange with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Sardinia, Corsica (+3 more), Monaco, France, Spain
Exclusive Deal
INSIDE
$2,599
OCEANVIEW
$3,099
BALCONY
$5,099
SUITE
$6,399
Save (per person) 2,599
From (per person) 2,599
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 June 2026
Countries Visited: Italy, France, Spain
Bonus Onboard Credit
INSIDE
$1,510
OCEANVIEW
$1,799
BALCONY
$2,509
SUITE
$3,860
Save (per person) 574
From (per person) 1,510
View Trip
8 Day Mediterranean Cruise: Itlay, France & Spain with Azamara Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 07 November 2026
Countries Visited: Italy, France, Spain
INSIDE
$2,079
OCEANVIEW
$2,409
BALCONY
$2,699
SUITE
$4,249
From (per person) 2,079
View Trip
22 Day An Extended Journey Of Roman Ruins, Coastal Adventures And Urban Delights with Explora Journeys
Cruise

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 07 July 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+4 more), France, Monaco, Corsica, Sardinia
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$13,005
SUITE
$14,535
From (per person) 13,005
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2026 to Aug 2026
Countries Visited: Italy, France, Spain
Bonus Onboard Credit
INSIDE
$1,541
OCEANVIEW
$1,828
BALCONY
$2,016
SUITE
$5,446
Save (per person) 915
From (per person) 1,541
View Trip
8 Day Mediterranean Marvels & Matches: Barcelona Open with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 13 April 2025
Countries Visited: Italy, France, Spain
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$3,399
From (per person) 3,399
View Trip
10 Day Italy to France & Spain with Virgin Voyages
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 07 October 2025
Countries Visited: Italy, Sardinia, Corsica, France (+1 more), Spain
Up To USD $300 Bar Tab
INSIDE
$1,665
OCEANVIEW
$2,115
BALCONY
$2,256
SUITE
$4,815
From (per person) 1,665
View Trip
11 Day Italy & France Spotlight with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 22 May 2026
Countries Visited: Italy, Sicily, Sardinia, Corsica (+2 more), France, Spain
Exclusive Deal
INSIDE
$3,199
OCEANVIEW
$3,549
BALCONY
$5,299
SUITE
$7,299
Save (per person) 3,199
From (per person) 3,199
View Trip
21 Day Am Extended Journey To Moroccan Medinas And Flavourful Andalusia with Explora Journeys
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 23 April 2025
Countries Visited: Italy, Spain, Morocco, Gibraltar (+1 more), Portugal
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,390
SUITE
$10,980
From (per person) 9,390
View Trip
21 Day France & Spanish Treasures with Seabourn
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: May 2025 to Jun 2025
Countries Visited: Italy, Malta, Tunisia, France (+3 more), Spain, Gibraltar, Morocco
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$10,199
SUITE
$21,589
From (per person) 10,199
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Sep 2026 to Oct 2026
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive Deal
INSIDE
$2,710
OCEANVIEW
$3,190
BALCONY
$4,380
SUITE
$4,844
From (per person) 2,710
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to May 2025
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive Deal
INSIDE
$3,111
OCEANVIEW
$3,951
BALCONY
$4,751
SUITE
$5,351
From (per person) 3,111
View Trip
8 Day A Journey To Ancient Marvels & Sparkling Shorelines with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+1 more), Spain
Unique Oceans OfferEarly Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$5,600
SUITE
$6,455
From (per person) 5,600
View Trip
8 Day Mediterranean Cruise From Rome To Barcelona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2026
Countries Visited: Italy, Sicily, France, Spain
INSIDE
$1,077
OCEANVIEW
-
BALCONY
$1,477
SUITE
$1,677
From (per person) 1,077
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 23 February 2026
Countries Visited: Italy, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$4,000
BALCONY
$4,800
SUITE
$9,400
Save (per person) 3,000
From (per person) 4,000
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 29 August 2026
Countries Visited: Italy, Corsica, France, Gibraltar (+1 more), Spain
Exclusive Deal
INSIDE
$1,324
OCEANVIEW
$1,524
BALCONY
$1,874
SUITE
$2,874
From (per person) 1,324
View Trip
15 Day Rome to Barcelona with Silversea
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departures: Jun 2026 to Jul 2026
Countries Visited: Italy, France, Monaco, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,100
From (per person) 11,100
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
One Way Cruise Offer
INSIDE
$209
OCEANVIEW
$249
BALCONY
$348
SUITE
$585
From (per person) 209
View Trip
8 Day Mediterranean Passage with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain
Exclusive Deal
INSIDE
$1,999
OCEANVIEW
$2,199
BALCONY
$3,199
SUITE
$4,499
Save (per person) 1,999
From (per person) 1,999
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 27 July 2026
Countries Visited: Italy, France, Spain
Bonus Onboard Credit
INSIDE
$1,386
OCEANVIEW
$1,426
BALCONY
$2,086
SUITE
$2,886
Save (per person) 527
From (per person) 1,386
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 06 September 2025
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive Deal
INSIDE
$3,499
OCEANVIEW
$4,069
BALCONY
$4,349
SUITE
$4,819
From (per person) 3,499
View Trip
31 Day Mediterranean Overture with Seabourn
Cruise

31 Days (30 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Sojourn
Departure: 06 September 2026
Countries Visited: Italy, France, Spain, Malta (+3 more), Tunisia, Sardinia, Corsica
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
$13,514
BALCONY
$15,384
SUITE
$26,774
From (per person) 13,514
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2025 to Sep 2026
Countries Visited: Italy, France, Spain
Bonus Onboard Credit
INSIDE
$1,456
OCEANVIEW
$1,671
BALCONY
$1,965
SUITE
$5,003
Save (per person) 1,110
From (per person) 1,456
View Trip
11 Day Riviera & Mediterranean Jewels with Seabourn
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Jun 2025 to Nov 2025
Countries Visited: Italy, Malta, Tunisia, France (+1 more), Spain
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,099
SUITE
$10,454
From (per person) 5,099
View Trip
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