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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September, June and July are the most popular months to cruise between Rome and Barcelona and there are 208 departures available from fifteen of the world's leading cruise lines.
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103 Cruises (208 Cruise Departures)
11 Day Grand Mediterranean with Princess
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Majestic Princess
Departure: 30 June 2025
Countries Visited: Italy, Greece, Turkey, Sicily (+1 more), Spain
Exclusive Deal
INSIDE
$3,070
OCEANVIEW
-
BALCONY
$3,775
SUITE
$4,526
From (per person) 3,070
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2025 to Sep 2026
Countries Visited: Italy, France, Spain
Exclusive DealNew Year Sale
INSIDE
$2,041
OCEANVIEW
$2,018
BALCONY
$2,458
SUITE
$7,721
Save (per person) 1,742
From (per person) 2,018
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Feb 2025 to Sep 2027
Countries Visited: Italy, Monaco, France, Spain
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$5,341
SUITE
$7,321
Save (per person) 2,262
From (per person) 5,341
View Trip
11 Day Italy & France Spotlight with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 22 May 2026
Countries Visited: Italy, Sicily, Sardinia, Corsica (+2 more), France, Spain
Exclusive Deal
INSIDE
$4,824
OCEANVIEW
$5,349
BALCONY
$7,982
SUITE
$10,992
Save (per person) 2,036
From (per person) 4,824
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Aug 2025
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive Deal
INSIDE
$3,875
OCEANVIEW
$4,999
BALCONY
$6,882
SUITE
$7,097
From (per person) 3,875
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2026 to Sep 2026
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive Deal
INSIDE
$3,797
OCEANVIEW
$4,650
BALCONY
$5,678
SUITE
$6,243
From (per person) 3,797
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 06 September 2025
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive Deal
INSIDE
$5,822
OCEANVIEW
$6,574
BALCONY
$7,208
SUITE
$7,950
From (per person) 5,822
View Trip
12 Day Grand Mediterranean with Princess
Cruise
 (2)

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 21 October 2025
Countries Visited: Italy, Greece, Turkey, Sicily (+1 more), Spain
Exclusive Deal
INSIDE
$3,439
OCEANVIEW
$4,072
BALCONY
$5,617
SUITE
$7,280
From (per person) 3,439
View Trip
8 Day Europe - Mediterranean with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2026
Countries Visited: Italy, Sicily, France, Spain
Exclusive Solo Offer
INSIDE
$2,396
OCEANVIEW
-
BALCONY
$3,008
SUITE
$3,313
From (per person) 2,396
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 07 September 2026
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$1,742
OCEANVIEW
$1,823
BALCONY
$2,526
SUITE
$3,647
Save (per person) 943
From (per person) 1,742
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 27 July 2026
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$1,898
OCEANVIEW
$1,967
BALCONY
$2,864
SUITE
$3,535
Save (per person) 1,021
From (per person) 1,898
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Sep 2026 to Oct 2026
Countries Visited: Italy, Sicily, Greece, Montenegro (+2 more), Turkey, Spain
Exclusive Deal
INSIDE
$3,976
OCEANVIEW
$4,584
BALCONY
$6,435
SUITE
$7,105
From (per person) 3,976
View Trip
12 Day Rivieras & Yacht Havens Voyage with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 26 August 2025
Countries Visited: Italy, Monaco, France, Spain
INSIDE
$4,714
OCEANVIEW
$5,080
BALCONY
$6,239
SUITE
$7,397
From (per person) 4,714
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 29 August 2026
Countries Visited: Italy, Corsica, France, Gibraltar (+1 more), Spain
Exclusive Deal
INSIDE
$1,914
OCEANVIEW
$2,211
BALCONY
$2,706
SUITE
$4,191
From (per person) 1,914
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$512
BALCONY
$621
SUITE
$1,017
From (per person) 512
View Trip
8 Day Mediterranean Holiday Cruise: Barcelona, Palma & Florence with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Countries Visited: Italy, Spain
INSIDE
$2,384
OCEANVIEW
$2,750
BALCONY
$3,552
SUITE
$5,621
From (per person) 2,384
View Trip
11 Day Mediterranean Melange with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Sardinia, Corsica (+3 more), Monaco, France, Spain
New Year Sale
INSIDE
$3,923
OCEANVIEW
$3,923
BALCONY
$4,973
SUITE
$9,636
From (per person) 3,923
View Trip
12 Day Grand Western Mediterranean with Princess
Cruise
 (2)

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 29 July 2025
Countries Visited: Italy, Sicily, France, Gibraltar (+1 more), Spain
Exclusive Deal
INSIDE
$2,235
OCEANVIEW
$2,770
BALCONY
$2,998
SUITE
$3,522
From (per person) 2,235
View Trip
8 Day Essential Mediterranean with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 June 2026
Countries Visited: Italy, Monaco, France, Spain
Exclusive Deal
INSIDE
$3,152
OCEANVIEW
$3,444
BALCONY
$5,156
SUITE
$7,159
Save (per person) 2,188
From (per person) 3,152
View Trip
9 Day Western Mediterranean Cruise: Italy, France & Spain with Azamara Cruises
Cruise
 (2)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 09 October 2025
Countries Visited: Italy, France, Spain
INSIDE
$3,810
OCEANVIEW
$3,919
BALCONY
$4,889
SUITE
$7,096
From (per person) 3,810
View Trip
8 Day Mediterranean Cruise: Itlay, France & Spain with Azamara Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 07 November 2026
Countries Visited: Italy, France, Spain
INSIDE
$2,908
OCEANVIEW
$3,393
BALCONY
$3,809
SUITE
$6,036
From (per person) 2,908
View Trip
11 Day Italy & Spain Cruise: Florence, Marseilles & Barcelona with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 March 2027
Countries Visited: Italy, France, Spain
INSIDE
$4,170
OCEANVIEW
$4,764
BALCONY
$5,912
SUITE
$8,793
From (per person) 4,170
View Trip
8 Day Mediterranean Passage with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain
Exclusive Deal
INSIDE
$3,020
OCEANVIEW
$3,317
BALCONY
$4,822
SUITE
$6,782
Save (per person) 2,020
From (per person) 3,020
View Trip
11 Day Autumnal Mediterranean with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+3 more), Monaco, France, Spain
Exclusive Deal
INSIDE
$4,076
OCEANVIEW
$4,343
BALCONY
$6,642
SUITE
$9,350
Save (per person) 2,484
From (per person) 4,076
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 June 2026
Countries Visited: Italy, France, Spain
Exclusive DealSingle Savings
INSIDE
$1,902
OCEANVIEW
$2,072
BALCONY
$3,084
SUITE
$4,426
Save (per person) 1,012
From (per person) 1,902
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jun 2026 to Jul 2026
Countries Visited: Italy, France, Gibraltar, Spain
Exclusive Deal
INSIDE
$1,865
OCEANVIEW
$2,162
BALCONY
$2,608
SUITE
$4,093
From (per person) 1,865
View Trip
8 Day Western Mediterranean Cruise: Italy, France & Spain with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 31 October 2026
Countries Visited: Italy, Monaco, France, Spain
INSIDE
$2,917
OCEANVIEW
$3,451
BALCONY
$4,006
SUITE
$5,520
From (per person) 2,917
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 05 August 2025
Countries Visited: Italy, France, Spain
New Year SaleExclusive Deal
INSIDE
$2,351
OCEANVIEW
$2,444
BALCONY
$2,551
SUITE
$8,678
Save (per person) 1,585
From (per person) 2,351
View Trip
17 Day Civitavecchia to Barcelona with Silversea
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Tunisia, France (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,513
From (per person) 18,513
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 January 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$6,831
BALCONY
$6,831
SUITE
$13,563
Save (per person) 2,569
From (per person) 6,831
View Trip
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