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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? June is the most popular month to cruise between Rome and Barcelona and there are 192 departures available from fifteen of the world's leading cruise lines.
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94 Cruises (192 Cruise Departures)
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Barcelona
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jul 2025 to Sep 2027
Countries Visited: Italy, Monaco, France, Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$2,599
SUITE
$3,799
Save (per person) 700
From (per person) 2,599
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Countries Visited: Italy, France, Corsica, Spain
Exclusive Deal
INSIDE
$2,149
OCEANVIEW
$2,369
BALCONY
$2,879
SUITE
$6,849
From (per person) 2,149
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 07 September 2026
Countries Visited: Italy, France, Spain
March Vacation Sale
INSIDE
$1,155
OCEANVIEW
$1,218
BALCONY
$1,755
SUITE
$2,512
Save (per person) 561
From (per person) 1,155
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 January 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$7,000
BALCONY
$8,000
SUITE
$18,400
From (per person) 7,000
View Trip
10 Day Tyrrhenian Yacht Treasures with Seabourn
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 05 May 2026
Countries Visited: Italy, Sicily, Sardinia, Corsica (+2 more), France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,699
From (per person) 8,699
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 October 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,000
From (per person) 10,000
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+2 more), Malta, Spain
Exclusive Deal
INSIDE
$2,299
OCEANVIEW
$2,469
BALCONY
$2,989
SUITE
$7,039
From (per person) 2,299
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
One Way Cruise Offer
INSIDE
$181
OCEANVIEW
$241
BALCONY
$341
SUITE
$591
From (per person) 181
View Trip
8 Day Mediterranean Holiday Cruise: Barcelona, Palma & Florence with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Countries Visited: Italy, Spain
INSIDE
$1,639
OCEANVIEW
$1,899
BALCONY
$2,459
SUITE
$3,899
From (per person) 1,639
View Trip
8 Day A Journey Of Shimmering Shores & Timeless Mediterranean Treasures with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jun 2026 to Sep 2026
Countries Visited: Italy, Corsica, France, Spain
Unique Oceans OfferExplora Early Booking Benefit
INSIDE
-
OCEANVIEW
-
BALCONY
$4,670
SUITE
$5,395
From (per person) 4,670
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 20 October 2025
Countries Visited: Italy, Sicily, France, Spain
March Vacation Sale
INSIDE
$845
OCEANVIEW
$1,050
BALCONY
$1,323
SUITE
-
Save (per person) 444
From (per person) 845
View Trip
9 Day Rome to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 10 November 2025
Countries Visited: Italy, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$6,400
BALCONY
$7,200
SUITE
$7,000
From (per person) 6,400
View Trip
22 Day An Extended Journey Of Roman Ruins, Coastal Adventures And Urban Delights with Explora Journeys
Cruise

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 07 July 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+4 more), France, Monaco, Corsica, Sardinia
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$24,165
From (per person) 24,165
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 May 2025
Countries Visited: Italy, Monaco, France, Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,950
From (per person) 7,950
View Trip
9 Day Western Mediterranean Cruise: Italy, France & Spain with Azamara Cruises
Cruise
 (2)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 09 October 2025
Countries Visited: Italy, France, Spain
INSIDE
$2,519
OCEANVIEW
$2,589
BALCONY
$3,349
SUITE
$4,689
From (per person) 2,519
View Trip
8 Day Mediterranean Cruise: Itlay, France & Spain with Azamara Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 07 November 2026
Countries Visited: Italy, France, Spain
INSIDE
$2,079
OCEANVIEW
$2,409
BALCONY
$2,699
SUITE
$4,249
From (per person) 2,079
View Trip
8 Day Mediterranean Passage with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain
Exclusive Deal
INSIDE
$1,999
OCEANVIEW
$2,199
BALCONY
$3,199
SUITE
$4,499
Save (per person) 1,999
From (per person) 1,999
View Trip
12 Day Grand Mediterranean with Princess
Cruise
 (2)

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 21 October 2025
Countries Visited: Italy, Greece, Turkey, Sicily (+1 more), Spain
Exclusive DealSpring Swing Offer
INSIDE
$1,570
OCEANVIEW
$2,016
BALCONY
$2,610
SUITE
$3,550
From (per person) 1,570
View Trip
8 Day Rome To Barcelona with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$1,009
OCEANVIEW
$1,139
BALCONY
$1,229
SUITE
$3,079
From (per person) 1,009
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jun 2026 to Jul 2026
Countries Visited: Italy, France, Gibraltar, Spain
Exclusive Deal
INSIDE
$1,275
OCEANVIEW
$1,473
BALCONY
$1,770
SUITE
$2,760
From (per person) 1,275
View Trip
11 Day Spanish Sapphire Shores with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 24 March 2027
Countries Visited: Italy, France, Spain
Exclusive DealEarly Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$7,999
SUITE
$9,399
Save (per person) 13,599
From (per person) 7,999
View Trip
8 Day Essential Mediterranean with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 June 2026
Countries Visited: Italy, Monaco, France, Spain
Exclusive Deal
INSIDE
$2,199
OCEANVIEW
$2,399
BALCONY
$3,599
SUITE
$4,999
Save (per person) 2,199
From (per person) 2,199
View Trip
11 Day Italy & France Spotlight with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 22 May 2026
Countries Visited: Italy, Sicily, Sardinia, Corsica (+2 more), France, Spain
Exclusive Deal
INSIDE
$3,199
OCEANVIEW
$3,549
BALCONY
$5,299
SUITE
$7,299
Save (per person) 3,199
From (per person) 3,199
View Trip
12 Day A Journey to Moroccan Medinas & Flavourful Andalusia with Explora Journeys
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 23 April 2025
Countries Visited: Italy, Spain, Morocco, Gibraltar
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,265
SUITE
$6,075
From (per person) 5,265
View Trip
11 Day Italy & Spain Cruise: Florence, Marseilles & Barcelona with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 March 2027
Countries Visited: Italy, France, Spain
INSIDE
$2,889
OCEANVIEW
$3,319
BALCONY
$4,119
SUITE
$6,119
From (per person) 2,889
View Trip
22 Day An Extended Journey Of Natural Delights And Historic Wonders with Explora Journeys
Cruise

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 18 August 2025
Countries Visited: Italy, Sicily, Sardinia, Spain (+2 more), France, Tunisia
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,280
From (per person) 14,280
View Trip
12 Day Grand Western Mediterranean with Princess
Cruise
 (2)

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 29 July 2025
Countries Visited: Italy, Sicily, France, Spain (+1 more), Gibraltar
Exclusive DealSpring Swing Offer
INSIDE
$1,528
OCEANVIEW
$1,687
BALCONY
$2,033
SUITE
$2,231
From (per person) 1,528
View Trip
8 Day A Journey Of Treasured Secrets & Chic Promenades with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 10 August 2026
Countries Visited: Italy, Monaco, France, Spain
Unique Oceans OfferExplora Early Booking Benefit
INSIDE
-
OCEANVIEW
-
BALCONY
$4,670
SUITE
$5,395
From (per person) 4,670
View Trip
9 Day Springtime Rivieras with Oceania Cruises
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 May 2025
Countries Visited: Italy, Corsica, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$3,499
BALCONY
$4,599
SUITE
-
Save (per person) 3,499
From (per person) 3,499
View Trip
10 Day Rome to Barcelona with Silversea
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,800
From (per person) 9,800
View Trip
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