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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 202 departures available from fifteen of the world's leading cruise lines.
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103 Cruises (202 Cruise Departures)
8 Day Mediterranean with France & Italy with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Oct 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,731
OCEANVIEW
$1,952
BALCONY
$2,128
SUITE
$2,427
From (per person) 1,731
View Trip
10 Day Greece, Malta & Turkey Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 30 August 2025
Countries Visited: Spain, Malta, Greece, Turkey (+1 more), Italy
Exclusive DealNew Year Sale
INSIDE
$2,933
OCEANVIEW
$3,319
BALCONY
$3,684
SUITE
$6,403
From (per person) 4,739
View Trip
8 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 08 August 2026
Countries Visited: Spain, Gibraltar, Italy
Exclusive Deal
INSIDE
$3,289
OCEANVIEW
$4,566
BALCONY
$5,764
SUITE
$6,397
From (per person) 3,289
View Trip
11 Day Charmed Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 21 April 2026
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Exclusive Deal
INSIDE
$4,585
OCEANVIEW
$5,084
BALCONY
$7,228
SUITE
$10,012
Save (per person) 2,275
From (per person) 4,585
View Trip
8 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2026
Countries Visited: Spain, France, Italy, Sicily
Exclusive Solo Offer
INSIDE
$2,537
OCEANVIEW
-
BALCONY
$3,149
SUITE
$3,455
From (per person) 2,537
View Trip
27 Day Ramblas To Renaissance with Oceania Cruises
Cruise
 (1)

27 Days (26 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 December 2026
Countries Visited: Spain, Gibraltar, Morocco, Portugal (+3 more), France, Italy, Corsica
Exclusive Deal
INSIDE
$10,865
OCEANVIEW
$11,914
BALCONY
$18,082
SUITE
$25,141
Save (per person) 2,075
From (per person) 10,865
View Trip
10 Day France Intensive Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 April 2025
Countries Visited: Spain, France, Corsica, Italy
INSIDE
$3,039
OCEANVIEW
$3,247
BALCONY
$4,366
SUITE
$7,049
From (per person) 3,039
View Trip
9 Day Spain & Italy Cruise: Barcelona, Portofino & Florence with Azamara Cruises
Cruise
 (1)

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 09 April 2026
Countries Visited: Spain, France, Italy
INSIDE
$2,671
OCEANVIEW
$3,186
BALCONY
$4,097
SUITE
$5,691
From (per person) 2,671
View Trip
8 Day Costa Brave & Italy with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 October 2026
Countries Visited: Spain, France, Corsica, Italy (+1 more), Sardinia
Exclusive Deal
INSIDE
$3,169
OCEANVIEW
$3,476
BALCONY
$5,129
SUITE
$7,080
Save (per person) 2,021
From (per person) 3,169
View Trip
7 Day Mediterranean with France & Italy with Princess
Cruise
 (2)

7 Days (6 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 March 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,549
OCEANVIEW
$1,811
BALCONY
$1,964
SUITE
$2,130
From (per person) 1,549
View Trip
8 Day Southern France and the Italian Riviera by Sea - with Smithsonian Journeys with Ponant
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 02 October 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,281
SUITE
$15,641
Save (per person) 179
From (per person) 9,281
View Trip
13 Day French & Italian Treasures with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 30 September 2026
Countries Visited: Spain, France, Italy, Corsica (+3 more), Sardinia, Sicily, Malta
Exclusive Deal
INSIDE
$5,431
OCEANVIEW
$6,035
BALCONY
$9,342
SUITE
$12,945
Save (per person) 2,039
From (per person) 5,431
View Trip
28 Day Solar Eclipse Collectors' Voyage: Iberia & Italy with Holland America
Cruise
 (2)

28 Days (27 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 August 2026
Countries Visited: Spain, Morocco, Portugal, Corsica (+4 more), Italy, Montenegro, Greece, Sicily
Exclusive Deal
INSIDE
$7,224
OCEANVIEW
$8,115
BALCONY
-
SUITE
-
From (per person) 7,224
View Trip
8 Day Yachting Havens with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 May 2026
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$3,152
OCEANVIEW
$3,444
BALCONY
$5,156
SUITE
$7,159
Save (per person) 2,188
From (per person) 3,152
View Trip
15 Day Malta, Greece & Amalfi Coast Collectors' Voyage with Holland America
Cruise
 (2)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 12 July 2026
Countries Visited: Spain, Malta, Greece, Turkey (+3 more), Montenegro, Sicily, Italy
Exclusive Deal
INSIDE
$3,633
OCEANVIEW
$4,227
BALCONY
$5,217
SUITE
$8,088
From (per person) 3,633
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Majestic Princess
Departure: 04 March 2025
Countries Visited: Spain, Gibraltar, Corsica, Italy
Exclusive Deal
INSIDE
$1,631
OCEANVIEW
-
BALCONY
$2,253
SUITE
$2,512
From (per person) 1,631
View Trip
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Countries Visited: Spain, France, Italy
INSIDE
$2,504
OCEANVIEW
$2,870
BALCONY
$3,682
SUITE
$5,751
From (per person) 2,504
View Trip
10 Day Italy & Spain Cruise: Florence, Portofino & Barcelona with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 August 2026
Countries Visited: Spain, France, Monaco, Italy
INSIDE
$2,930
OCEANVIEW
$3,692
BALCONY
$4,514
SUITE
$7,167
From (per person) 2,930
View Trip
12 Day Spain & Italy Cruise: Barcelona, Salerno & Rome with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 February 2027
Countries Visited: Spain, Sardinia, Tunisia, Malta (+2 more), Sicily, Italy
INSIDE
$4,407
OCEANVIEW
$5,120
BALCONY
$6,387
SUITE
$9,485
From (per person) 4,407
View Trip
8 Day Southern France and the Italian Riviera by Sea – with Smithsonian Journeys with Ponant
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 26 April 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,761
SUITE
$14,818
Save (per person) 189
From (per person) 9,761
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sicily
Exclusive Deal
INSIDE
$3,271
OCEANVIEW
$3,568
BALCONY
$4,063
SUITE
$8,468
From (per person) 3,271
View Trip
8 Day A Journey Through The Soul Of The Mediterranean's Eternal Beauty with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 June 2026
Countries Visited: Spain, Corsica, Sardinia, Italy (+1 more), France
Unique Oceans OfferExplora Early Booking Benefit
INSIDE
-
OCEANVIEW
-
BALCONY
$8,207
SUITE
$9,435
From (per person) 8,207
View Trip
11 Day Greek Isles & Turkey with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Apr 2026 to May 2026
Countries Visited: Spain, Malta, Greece, Turkey (+1 more), Italy
Exclusive DealNew Year Sale
INSIDE
$2,480
OCEANVIEW
$2,789
BALCONY
$3,218
SUITE
$8,205
Save (per person) 1,736
From (per person) 2,480
View Trip
13 Day Total Eclipse of the (Med) with Virgin Voyages
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 10 August 2026
Countries Visited: Spain, France, Corsica, Italy (+1 more), Sicily
80% Off Second SailorUp To USD $300 Bar Tab
INSIDE
$6,349
OCEANVIEW
$7,033
BALCONY
$7,423
SUITE
$16,305
From (per person) 6,349
View Trip
31 Day Jewels Of Spain, Italy & France with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 July 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
Sail Of The Year
INSIDE
-
OCEANVIEW
-
BALCONY
$26,347
SUITE
$41,600
From (per person) 26,347
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 June 2026
Countries Visited: Spain, Sardinia, Tunisia, Sicily (+1 more), Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,999
Save (per person) 4,101
From (per person) 9,999
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy
Exclusive Deal
INSIDE
$1,932
OCEANVIEW
$2,031
BALCONY
$2,328
SUITE
$5,050
From (per person) 1,932
View Trip
9 Day Mediterranean Marvels & Matches: Monte Carlo Masters with Seabourn
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 05 April 2025
Countries Visited: Spain, France, Monaco, Italy
Sail Of The Year
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,834
From (per person) 7,834
View Trip
22 Day An Extended Journey From Island Bliss To The Secrets Of Ancient Cities with Explora Journeys
Cruise

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 16 June 2025
Countries Visited: Spain, France, Monaco, Corsica (+3 more), Italy, Sardinia, Sicily
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$21,339
SUITE
$22,810
From (per person) 21,339
View Trip
31 Day Mediterranean Magic & Solar Eclipse with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Sojourn
Departure: 07 August 2026
Countries Visited: Spain, France, Italy, Monaco (+4 more), Corsica, Sardinia, Sicily, Albania
Sail Of The Year
INSIDE
-
OCEANVIEW
$23,509
BALCONY
$25,949
SUITE
$58,275
From (per person) 23,509
View Trip
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