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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 207 departures available from sixteen of the world's leading cruise lines.
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97 Cruises (207 Cruise Departures)
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,421
Oceanview
$3,955
Balcony
$4,496
Suite
$6,293
From
US$3,421
Save 3,577
Per Person
View Trip
11 Day Spain, Portugal & France Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 24 July 2027
Visit: Spain, Gibraltar, Portugal, Corsica, Italy
Exclusive Savings
Inside
$1,704
Oceanview
$1,925
Balcony
$2,067
Suite
$5,125
From
US$2,563
Per Person
View Trip
13 Day French & Italian Treasures with Oceania Cruises
Cruise
 (3)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 30 September 2026
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily, Malta
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$3,518
Oceanview
$3,906
Balcony
$6,040
Suite
$8,368
From
US$3,518
Save 3,680
Per Person
View Trip
10 Day Western Med: Barcelona to Rome with Virgin Voyages
Cruise
 (5)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 08 August 2027
Visit: Spain, France, Italy, Sicily, Malta
With Love From the World
Inside
$1,881
Oceanview
$2,364
Balcony
$2,331
Suite
$5,535
From
US$1,881
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Visit: Spain, Corsica, Sicily, Italy
Inside
$1,179
Oceanview
$1,399
Balcony
$1,649
Suite
$2,589
From
US$1,179
Per Person
View Trip
8 Day Elegant Shores with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 April 2026
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,092
Suite
$6,729
From
US$6,092
Save 10,706
Per Person
View Trip
10 Day Italy & Spain Cruise: Florence, Portofino & Barcelona with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 August 2026
Visit: Spain, France, Monaco, Italy
Azamara Always Included
Exclusive Savings
Inside
$2,329
Oceanview
$2,736
Balcony
$3,279
Suite
$5,462
From
US$2,329
Save 50
Per Person
View Trip
12 Day Picturesque Panoramas with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 22 August 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,135
Suite
$10,605
From
US$9,135
Save 15,463
Per Person
View Trip
12 Day Spain & Italy Cruise: Barcelona, Salerno & Rome with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 February 2027
Visit: Spain, Sardinia, Tunisia, Malta, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,672
Oceanview
$4,293
Balcony
$4,924
Suite
$7,669
From
US$3,672
Save 87
Per Person
View Trip
11 Day Greek Isles & Malta Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Apr 2026 to Oct 2027
Visit: Spain, Malta, Greece, Turkey, Italy
Exclusive Savings
Inside
$1,849
Oceanview
$1,974
Balcony
$2,256
Suite
$5,384
From
US$2,769
Save 95
Per Person
View Trip
13 Day Total Eclipse of the (Med) with Virgin Voyages
Cruise
 (1)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 10 August 2026
Visit: Spain, France, Corsica, Italy, Sicily
With Love From the World
Inside
$3,228
Oceanview
$3,468
Balcony
$3,708
Suite
$8,748
From
US$3,228
Per Person
View Trip
11 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2027 to Aug 2027
Visit: Spain, Morocco, Portugal, Corsica, Italy
Exclusive Savings
Inside
$1,834
Oceanview
$1,934
Balcony
$2,034
Suite
$5,228
From
US$2,768
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2026 to Jul 2026
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,329
Oceanview
$1,719
Balcony
$1,939
Suite
$2,099
From
US$1,329
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily, Italy
Inside
$1,569
Oceanview
-
Balcony
$2,059
Suite
$6,982
From
US$1,569
Per Person
View Trip
12 Day Cultures of the Mediterranean Barcelona to Civitavecchia with Emerald Cruises
New ReleaseCruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: May 2027 to Sep 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Fly Free Economy
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$8,527
Balcony
-
Suite
$11,825
From
US$8,527
Save 11,463
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 15 June 2026
Visit: Spain, France, Italy, Sardinia, Corsica, Sicily
Inside
$2,359
Oceanview
$2,439
Balcony
$2,759
Suite
$5,609
From
US$2,359
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departure: 11 December 2026
Visit: Spain, France, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$1,099
From
US$1,099
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 05 September 2027
Visit: Spain, France, Italy, Corsica
Princess Standard
Sanctuary Collection
Inside
$1,189
Oceanview
$1,399
Balcony
$1,489
Suite
$1,839
From
US$1,189
Per Person
View Trip
11 Day Greek Isles & Turkey with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2026 to Sep 2026
Visit: Spain, Malta, Greece, Turkey, Italy
Exclusive Savings
Inside
$2,035
Oceanview
$2,174
Balcony
$2,252
Suite
$5,979
From
US$3,006
Save 126
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,399
Oceanview
$2,699
Balcony
$2,909
Suite
$6,164
From
US$2,399
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 25 April 2026
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,230
Oceanview
$1,610
Balcony
$1,940
Suite
$2,210
From
US$1,230
Per Person
View Trip
8 Day Etruscan Waterways with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 21 April 2026
Visit: Spain, France, Italy, Corsica, Sardinia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,541
Oceanview
$3,075
Balcony
$3,511
Suite
-
From
US$2,541
Save 2,657
Per Person
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 19 May 2026
Visit: Spain, France, Monaco, Italy
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$5,850
Suite
$11,135
From
US$5,850
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+10 more), Viking Libra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2026 to Jul 2028
Visit: Spain, France, Monaco, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,999
From
US$2,599
Save 500
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 17 October 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,933
From
US$3,933
Save 116
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily (+5 more), Italy, Greece, Montenegro, Croatia, Malta
Inside
$3,529
Oceanview
$4,159
Balcony
$5,809
Suite
$8,819
From
US$3,529
Per Person
View Trip
8 Day Yachting Havens with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 May 2026
Visit: Spain, France, Italy
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$2,160
Balcony
$3,164
Suite
$7,781
From
US$2,160
Save 2,638
Per Person
View Trip
15 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 10 September 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy, Greece, Sicily
Inside
$1,869
Oceanview
$2,129
Balcony
$2,639
Suite
$5,758
From
US$1,869
Per Person
View Trip
10 Day Under The Tuscan Sunset with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 17 June 2027
Visit: Spain, Corsica, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,347
Suite
$8,543
From
US$8,347
Save 13,651
Per Person
View Trip
8 Day Regal Retreat with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 June 2027
Visit: Spain, France, Monaco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,797
Suite
$6,581
From
US$5,797
Save 11,001
Per Person
View Trip
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