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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 204 departures available from sixteen of the world's leading cruise lines.
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97 Cruises (204 Cruise Departures)
10 Day Toast To Toulon with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 31 August 2027
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,642
Suite
$9,034
From
US$8,642
Save 13,956
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Visit: Spain, France, Italy, Corsica, Sicily
Inside
$2,639
Oceanview
$2,969
Balcony
$4,169
Suite
$5,866
From
US$2,639
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 September 2026
Visit: Spain, Corsica, France, Italy
Princess Standard
Sanctuary Collection
Inside
$1,564
Oceanview
$1,964
Balcony
$2,389
Suite
$2,789
From
US$1,564
Per Person
View Trip
8 Day Elegant Shores with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 April 2026
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,582
Suite
$6,876
From
US$6,582
Save 11,216
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+10 more), Viking Libra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2026 to Jul 2028
Visit: Spain, France, Monaco, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,699
Suite
$3,499
From
US$2,699
Save 950
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$999
Oceanview
$1,649
Balcony
$1,499
Suite
$1,769
From
US$999
Per Person
View Trip
15 Day A Holiday To Remember with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 20 December 2027
Visit: Spain, Morocco, Tunisia, Sicily, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,047
Suite
$8,278
From
US$6,047
Save 6,351
Per Person
View Trip
10 Day Eclipse The Ordinary with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 July 2027
Visit: Spain, Malta, Sicily, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,768
Suite
$10,454
From
US$9,768
Save 15,130
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,399
Oceanview
$2,699
Balcony
$2,909
Suite
$6,164
From
US$2,399
Per Person
View Trip
15 Day Italy, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,489
Oceanview
$2,719
Balcony
$2,929
Suite
$6,184
From
US$2,489
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 05 September 2027
Visit: Spain, France, Italy, Corsica
Princess Standard
Sanctuary Collection
Inside
$1,114
Oceanview
$1,444
Balcony
$1,639
Suite
$2,019
From
US$1,114
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Oct 2026 to Oct 2027
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,174
Oceanview
$1,324
Balcony
$1,519
Suite
$1,819
From
US$1,174
Per Person
View Trip
8 Day Mediterranean Holiday with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2026
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$2,446
Oceanview
$2,786
Balcony
$3,707
Suite
$4,774
From
US$2,446
Save 2,552
Per Person
View Trip
16 Day Barcelona to Civitavecchia with Silversea
Cruise

16 Days (15 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 June 2026
Visit: Spain, France, Monaco, Italy
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,200
Suite
$13,500
From
US$8,200
Per Person
View Trip
27 Day Ramblas To Renaissance with Oceania Cruises
Cruise
 (1)

27 Days (26 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 December 2026
Visit: Spain, Gibraltar, Morocco, Portugal, France, Italy, Corsica
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$7,285
Oceanview
$7,673
Balcony
$11,699
Suite
$16,694
From
US$7,285
Save 7,613
Per Person
View Trip
11 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 18 September 2027
Visit: Spain, Morocco, Portugal, Sardinia, Italy
Exclusive Savings
Inside
$2,196
Oceanview
$2,438
Balcony
$2,606
Suite
$6,941
From
US$2,597
Save 851
Per Person
View Trip
8 Day Luminous Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 October 2026
Visit: Spain, France, Italy
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,245
Suite
$4,488
From
US$3,245
Save 3,753
Per Person
View Trip
21 Day Barcelona to Rome with Silversea
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Visit: Spain, France, Monaco, Corsica, Italy, Sicily
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$12,200
Suite
$27,700
From
US$12,200
Per Person
View Trip
15 Day Malta, Greece & Amalfi Coast Collectors' Voyage with Holland America
Cruise
 (2)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jul 2026 to Jun 2027
Visit: Spain, Malta, Greece, Turkey, Montenegro, Sicily, Italy
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,404
Oceanview
$2,554
Balcony
$3,390
Suite
$5,419
From
US$2,404
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$919
Oceanview
$1,699
Balcony
$1,349
Suite
$1,639
From
US$919
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2026 to Jul 2026
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$1,404
Oceanview
$1,774
Balcony
$2,264
Suite
$2,557
From
US$1,404
Save 74
Per Person
View Trip
10 Day Epicurean Odyssey with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 September 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,693
Balcony
$4,196
Suite
$6,136
From
US$2,499
Save 2,499
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2027 to Aug 2027
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,064
Oceanview
$1,444
Balcony
$1,669
Suite
$1,839
From
US$1,064
Per Person
View Trip
8 Day Spain, France & Italy with Seabourn
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia, Italy
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,345
Suite
$8,594
From
US$5,345
Save 94
Per Person
View Trip
10 Day Ramblas & The Rivieras with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 05 September 2026
Visit: Spain, France, Monaco, Italy (+4 more), Corsica, Sardinia, Sicily, Malta
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,167
Suite
$7,058
From
US$5,167
Save 5,431
Per Person
View Trip
12 Day Best Of Italy, France & Spain with Celebrity Cruises
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 24 May 2027
Visit: Spain, Corsica, France, Italy, Sicily
Exclusive Savings
Inside
$2,104
Oceanview
$2,260
Balcony
$2,481
Suite
$6,451
From
US$2,478
Save 799
Per Person
View Trip
10 Day Italy & Spain Cruise: Florence, Portofino & Barcelona with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 August 2026
Visit: Spain, France, Monaco, Italy
Azamara Always Included
Exclusive Savings
Inside
$2,542
Oceanview
$3,037
Balcony
$3,628
Suite
$6,024
From
US$2,542
Save 57
Per Person
View Trip
8 Day Costa Brave & Italy with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 29 October 2026
Visit: Spain, France, Corsica, Italy, Sardinia
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$1,960
Balcony
$2,658
Suite
$3,667
From
US$1,960
Save 2,938
Per Person
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,421
Oceanview
$4,003
Balcony
$3,829
Suite
$5,381
From
US$3,421
Save 3,577
Per Person
View Trip
11 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2027 to Aug 2027
Visit: Spain, Morocco, Portugal, Corsica, Italy
Exclusive Savings
Inside
$2,037
Oceanview
$2,187
Balcony
$2,234
Suite
$6,818
From
US$2,408
Save 803
Per Person
View Trip
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