Home > Cruises > Europe Cruises > Mediterranean Cruises > Cruises from Barcelona to Rome

Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 253 departures available from sixteen of the world's leading cruise lines.
Filter Results
Departures
Show More...
Duration
4 Days
29 Days
Regions
Ship Size
Ship Features
Operators
Show More...
Price
$300pp
$30,598pp
Countries
Show More...
Filter Results
106 Cruises (253 Cruise Departures)
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sicily
Exclusive Deal
INSIDE
$1,929
OCEANVIEW
$2,109
BALCONY
$2,519
SUITE
$6,329
From (per person) 1,929
View Trip
15 Day Italy, Greece, and Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 August 2027
Countries Visited: Spain, Malta, Montenegro, Croatia (+3 more), Italy, Greece, Sicily
Exclusive Deal
INSIDE
$2,809
OCEANVIEW
$3,159
BALCONY
$3,809
SUITE
$8,659
From (per person) 2,809
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 November 2025
Countries Visited: Spain, France, Italy
One Way Cruise Offer
INSIDE
$319
OCEANVIEW
$389
BALCONY
$479
SUITE
-
From (per person) 319
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 16 June 2025
Countries Visited: Spain, France, Sardinia, Sicily (+1 more), Italy
Exclusive Deal
INSIDE
$1,429
OCEANVIEW
$1,549
BALCONY
$1,939
SUITE
$5,229
From (per person) 1,429
View Trip
11 Day Grand Mediterranean with Princess
Cruise
 (2)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 11 October 2025
Countries Visited: Spain, France, Italy, Montenegro (+1 more), Greece
Exclusive DealSpring Swing Offer
INSIDE
$1,380
OCEANVIEW
$1,776
BALCONY
$2,024
SUITE
$2,321
From (per person) 1,380
View Trip
22 Day Italy, Spain, Greece And Adriatic with Cunard
Cruise

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 11 June 2027
Countries Visited: Spain, Corsica, Italy, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Exclusive Deal
INSIDE
$3,819
OCEANVIEW
$4,119
BALCONY
$5,119
SUITE
$11,419
From (per person) 3,819
View Trip
8 Day Mediterranean with Princess
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 01 March 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive DealSpring Swing Offer
INSIDE
$1,162
OCEANVIEW
$1,221
BALCONY
$1,271
SUITE
$1,825
From (per person) 1,162
View Trip
8 Day Yachting Havens with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 May 2026
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$2,199
OCEANVIEW
$2,399
BALCONY
$3,599
SUITE
$4,999
Save (per person) 2,199
From (per person) 2,199
View Trip
8 Day A Journey to the Cote d'Azur & Olive-Scented Isles with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 08 September 2025
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,700
SUITE
$6,555
From (per person) 5,700
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Oct 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive DealSpring Swing Offer
INSIDE
$795
OCEANVIEW
$1,082
BALCONY
$1,411
SUITE
$1,559
From (per person) 795
View Trip
10 Day France Intensive Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 April 2025
Countries Visited: Spain, France, Corsica, Italy
Azamara Circle Loyalty Quarterly Savings
INSIDE
$1,599
OCEANVIEW
$1,709
BALCONY
-
SUITE
-
From (per person) 1,599
View Trip
9 Day Spain & Italy Cruise: Barcelona, Portofino & Florence with Azamara Cruises
Cruise
 (1)

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 09 April 2026
Countries Visited: Spain, France, Italy
INSIDE
$2,129
OCEANVIEW
$2,399
BALCONY
$3,089
SUITE
$4,309
From (per person) 2,129
View Trip
28 Day Solar Eclipse Collectors' Voyage: Iberia & Italy with Holland America
Cruise
 (2)

28 Days (27 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 August 2026
Countries Visited: Spain, Morocco, Portugal, Corsica (+4 more), Italy, Montenegro, Greece, Sicily
Exclusive Deal
INSIDE
$5,838
OCEANVIEW
$6,630
BALCONY
-
SUITE
-
From (per person) 5,838
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
$3,299
OCEANVIEW
$4,049
BALCONY
$4,699
SUITE
$6,799
Save (per person) 3,299
From (per person) 3,299
View Trip
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Countries Visited: Spain, Italy, Sicily, Greece (+3 more), Montenegro, Croatia, Malta
Exclusive Deal
INSIDE
$2,289
OCEANVIEW
$2,459
BALCONY
$2,979
SUITE
$7,019
From (per person) 2,289
View Trip
8 Day Italy And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Countries Visited: Spain, Sardinia, Sicily, Italy
Exclusive Deal
INSIDE
$1,119
OCEANVIEW
$1,249
BALCONY
$1,509
SUITE
$3,699
From (per person) 1,119
View Trip
22 Day An Extended Journey Through Old-world Elegance And Beautiful Island Beaches with Explora Journeys
Cruise

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Jul 2025
Countries Visited: Spain, France, Italy, Sicily (+4 more), Tunisia, Monaco, Corsica, Sardinia
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$15,390
From (per person) 15,390
View Trip
22 Day An Extended Journey Of Iconic Sophistication And Sparkling Cerulean Seas with Explora Journeys
Cruise

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 July 2025
Countries Visited: Spain, France, Monaco, Corsica (+3 more), Sardinia, Italy, Sicily
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,535
From (per person) 14,535
View Trip
15 Day Barcelona to Rome with Silversea
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 26 July 2026
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,200
From (per person) 11,200
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 19 May 2026
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,900
From (per person) 9,900
View Trip
12 Day Enchanted Evenings with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 18 September 2026
Countries Visited: Spain, Monaco, Italy
Exclusive DealEarly Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$9,499
SUITE
$11,199
Save (per person) 15,099
From (per person) 9,499
View Trip
8 Day Mediterranean Spring with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 06 May 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$3,049
BALCONY
$4,499
SUITE
-
Save (per person) 3,049
From (per person) 3,049
View Trip
12 Day Ancient Mediterranean Shores with Viking Cruises
Cruise

12 Days (11 Nights) Barcelona to Rome
Operated By: Viking Cruises
Ship: Viking Saturn
Departures: Feb 2026 to Feb 2026
Countries Visited: Spain, Malta, Greece, Turkey (+2 more), Sicily, Italy
Viking $999 Air Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$4,699
SUITE
$6,999
From (per person) 4,699
View Trip
8 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 08 August 2026
Countries Visited: Spain, Gibraltar, Italy
Exclusive DealSpring Swing Offer
INSIDE
$2,061
OCEANVIEW
$2,833
BALCONY
$3,576
SUITE
$3,972
From (per person) 2,061
View Trip
21 Day Barcelona to Rome with Silversea
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Countries Visited: Spain, France, Monaco, Corsica (+2 more), Italy, Sicily
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,300
From (per person) 14,300
View Trip
8 Day Southern France and the Italian Riviera by Sea – with Smithsonian Journeys with Ponant
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 26 April 2025
Countries Visited: Spain, France, Italy
INSIDE
-
OCEANVIEW
-
BALCONY
$7,620
SUITE
$11,500
From (per person) 7,620
View Trip
10 Day Greece, Malta & Turkey Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 30 August 2025
Countries Visited: Spain, Malta, Greece, Turkey (+1 more), Italy
Exclusive DealExclusive Solo Offer
INSIDE
$1,287
OCEANVIEW
$1,829
BALCONY
$1,956
SUITE
$9,676
Save (per person) 881
From (per person) 1,462
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Countries Visited: Spain, Corsica, Sicily, Italy
Exclusive Deal
INSIDE
$1,009
OCEANVIEW
$1,139
BALCONY
$1,369
SUITE
$3,269
From (per person) 1,009
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Barcelona to Rome
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jul 2025 to Sep 2027
Countries Visited: Spain, France, Monaco, Italy
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$2,599
SUITE
$3,799
Save (per person) 700
From (per person) 2,599
View Trip
8 Day Southern France and the Italian Riviera by Sea - with Smithsonian Journeys with Ponant
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 02 October 2025
Countries Visited: Spain, France, Italy
INSIDE
-
OCEANVIEW
-
BALCONY
$8,430
SUITE
$12,790
From (per person) 8,430
View Trip
Results: 1-30 of 106

No Results found. Try changing your search filters.




Cruises found! Scroll up to view

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Black Sea Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Food & Wine Cruises Luxury Cruises Short Cruise Breaks

Countries

Albania Corsica Croatia Cyprus England France Gibraltar Italy Malta Mexico Monaco Montenegro Morocco Portugal Sardinia Sicily Spain Tunisia Turkey USA

Cities

Barcelona

Routes

Cruises from Barcelona to Rome Cruises from Barcelona to Venice Cruises from Barcelona to Trieste

Country Routes

Cruises from Spain to Italy

Cruise Lines Exploring The Med

Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2025. Global Journeys. You're viewing our site in US dollars.

    

About Us | View Your Booking | Terms & Conditions | Site Map

Global Journeys Travel Inc. Member of American Society of Travel Advisors (ASTA No: 900374670) & TICO Accredited (No. 50027921).

Travel Industry Associations