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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 197 departures available from sixteen of the world's leading cruise lines.
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98 Cruises (197 Cruise Departures)
8 Day Mediterranean with France & Italy with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Oct 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,651
OCEANVIEW
$1,952
BALCONY
$2,128
SUITE
$2,427
From (per person) 1,651
View Trip
10 Day Greece, Malta & Turkey Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 30 August 2025
Countries Visited: Spain, Malta, Greece, Turkey (+1 more), Italy
Summer SaleExclusive Deal
INSIDE
$2,967
OCEANVIEW
$4,484
BALCONY
$4,175
SUITE
$6,462
Save (per person) 1,710
From (per person) 2,967
View Trip
8 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 08 August 2026
Countries Visited: Spain, Gibraltar, Italy
Exclusive Deal
INSIDE
$2,967
OCEANVIEW
$3,848
BALCONY
$5,234
SUITE
$5,739
From (per person) 2,967
View Trip
9 Day Spain & Italy Cruise: Barcelona, Portofino & Florence with Azamara Cruises
Cruise
 (1)

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 09 April 2026
Countries Visited: Spain, France, Italy
INSIDE
$2,671
OCEANVIEW
$3,186
BALCONY
$4,097
SUITE
$5,691
From (per person) 2,671
View Trip
10 Day Italy & Spain Cruise: Florence, Portofino & Barcelona with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 August 2026
Countries Visited: Spain, France, Monaco, Italy
INSIDE
$2,930
OCEANVIEW
$3,692
BALCONY
$4,514
SUITE
$7,167
From (per person) 2,930
View Trip
27 Day Ramblas To Renaissance with Oceania Cruises
Cruise
 (1)

27 Days (26 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 December 2026
Countries Visited: Spain, Gibraltar, Morocco, Portugal (+3 more), France, Italy, Corsica
Exclusive Deal
INSIDE
$10,865
OCEANVIEW
$11,914
BALCONY
$18,082
SUITE
$25,141
Save (per person) 2,075
From (per person) 10,865
View Trip
11 Day Grand Mediterranean with Princess
Cruise
 (2)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 11 October 2025
Countries Visited: Spain, France, Italy, Montenegro (+1 more), Greece
Exclusive Deal
INSIDE
$2,706
OCEANVIEW
$3,339
BALCONY
$4,102
SUITE
$4,686
From (per person) 2,706
View Trip
8 Day Costa Brave & Italy with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 October 2026
Countries Visited: Spain, France, Corsica, Italy (+1 more), Sardinia
Exclusive Deal
INSIDE
$3,169
OCEANVIEW
$3,476
BALCONY
$5,129
SUITE
$7,080
Save (per person) 2,021
From (per person) 3,169
View Trip
10 Day France Intensive Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 April 2025
Countries Visited: Spain, France, Corsica, Italy
INSIDE
$4,197
OCEANVIEW
$4,405
BALCONY
$6,088
SUITE
$8,049
From (per person) 4,197
View Trip
15 Day Malta, Greece & Amalfi Coast Collectors' Voyage with Holland America
Cruise
 (2)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 12 July 2026
Countries Visited: Spain, Malta, Greece, Turkey (+3 more), Montenegro, Sicily, Italy
Have It All Offer
INSIDE
$3,633
OCEANVIEW
$4,227
BALCONY
$5,217
SUITE
$8,088
From (per person) 3,633
View Trip
11 Day Charmed Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 21 April 2026
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Flex FaresExclusive Deal
INSIDE
$4,585
OCEANVIEW
$5,084
BALCONY
$7,228
SUITE
$10,012
Save (per person) 2,275
From (per person) 4,585
View Trip
8 Day Southern France and the Italian Riviera by Sea – with Smithsonian Journeys with Ponant
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 26 April 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,840
SUITE
$14,818
Save (per person) 170
From (per person) 8,840
View Trip
7 Day Mediterranean with France & Italy with Princess
Cruise
 (2)

7 Days (6 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 March 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,486
OCEANVIEW
$1,734
BALCONY
$1,783
SUITE
$2,070
From (per person) 1,486
View Trip
28 Day Solar Eclipse Collectors' Voyage: Iberia & Italy with Holland America
Cruise
 (2)

28 Days (27 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 August 2026
Countries Visited: Spain, Morocco, Portugal, Corsica (+4 more), Italy, Montenegro, Greece, Sicily
Have It All Offer
INSIDE
$7,224
OCEANVIEW
$8,115
BALCONY
-
SUITE
-
From (per person) 7,224
View Trip
8 Day Mediterranean Spring with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 06 May 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$4,446
BALCONY
$6,634
SUITE
-
Save (per person) 2,034
From (per person) 4,446
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Majestic Princess
Departure: 04 March 2025
Countries Visited: Spain, Gibraltar, Corsica, Italy
Exclusive Deal
INSIDE
$1,353
OCEANVIEW
-
BALCONY
$1,667
SUITE
$1,779
From (per person) 1,353
View Trip
13 Day French & Italian Treasures with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 30 September 2026
Countries Visited: Spain, France, Italy, Corsica (+3 more), Sardinia, Sicily, Malta
Exclusive Deal
INSIDE
$5,431
OCEANVIEW
$6,035
BALCONY
$9,342
SUITE
$12,945
Save (per person) 2,039
From (per person) 5,431
View Trip
8 Day Southern France and the Italian Riviera by Sea - with Smithsonian Journeys with Ponant
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 02 October 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,791
SUITE
$14,769
Save (per person) 169
From (per person) 8,791
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 24 March 2025
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$748
SUITE
-
From (per person) 748
View Trip
8 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2026
Countries Visited: Spain, France, Italy, Sicily
Exclusive Solo Offer
INSIDE
$2,785
OCEANVIEW
-
BALCONY
$3,396
SUITE
$3,702
From (per person) 2,785
View Trip
8 Day Yachting Havens with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 May 2026
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$3,318
OCEANVIEW
$3,625
BALCONY
$5,426
SUITE
$7,535
Save (per person) 2,022
From (per person) 3,318
View Trip
21 Day Barcelona to Rome with Silversea
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Countries Visited: Spain, France, Monaco, Corsica (+2 more), Italy, Sicily
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$20,592
From (per person) 20,592
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2025 to Sep 2027
Countries Visited: Spain, France, Monaco, Italy
Limited Time Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$4,648
SUITE
$7,123
Save (per person) 877
From (per person) 4,648
View Trip
10 Day A Journey to Hidden Histories & Ancient Carthage with Explora Journeys
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 April 2025
Countries Visited: Spain, Sardinia, Tunisia, Sicily (+1 more), Italy
The Exclusive Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$6,687
SUITE
$7,900
From (per person) 6,687
View Trip
31 Day Mediterranean Overture with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Sojourn
Departure: 16 September 2026
Countries Visited: Spain, Malta, Tunisia, Sardinia (+3 more), Corsica, Italy, France
Exclusive Deal
INSIDE
-
OCEANVIEW
$20,921
BALCONY
$24,386
SUITE
$46,067
From (per person) 20,921
View Trip
11 Day Mediterranean Overture with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Monaco, Italy (+2 more), Corsica, Sardinia
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,340
SUITE
$16,840
From (per person) 8,340
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
Experience Like No Other
INSIDE
$6,523
OCEANVIEW
$7,236
BALCONY
$7,949
SUITE
$19,274
From (per person) 6,523
View Trip
12 Day Enchanted Evenings with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 18 September 2026
Countries Visited: Spain, Monaco, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,758
SUITE
$16,273
Save (per person) 6,622
From (per person) 13,758
View Trip
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia (+2 more), Montenegro, Greece
Experience Like No Other
INSIDE
$3,568
OCEANVIEW
$3,815
BALCONY
$4,607
SUITE
$8,617
From (per person) 3,568
View Trip
8 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 10 May 2026
Countries Visited: Spain, France, Italy, Sicily
INSIDE
$3,060
OCEANVIEW
$3,519
BALCONY
$4,819
SUITE
$5,431
From (per person) 3,060
View Trip
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