Home > Cruises > Europe Cruises > Mediterranean Cruises > Cruises from Rome to Lisbon

Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? May and November are the most popular months to cruise between Rome and Lisbon and there are 25 departures available from eight of the world's leading cruise lines.
Filter Results
Departures
Show More...
Duration
10 Days
21 Days
Ship Size
Ship Features
Operators
Show More...
Price
$2,700pp
$29,950pp
Countries
Show More...
Filter Results
24 Cruises (25 Cruise Departures)
13 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 01 November 2025
Countries Visited: Italy, Sicily, Spain, Morocco (+1 more), Portugal
Exclusive Solo Offer
INSIDE
$3,505
OCEANVIEW
-
BALCONY
$4,855
SUITE
$5,364
From (per person) 3,505
View Trip
11 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 18 November 2025
Countries Visited: Italy, France, Spain, Portugal
INSIDE
$4,402
OCEANVIEW
$4,938
BALCONY
$5,581
SUITE
$7,584
From (per person) 4,402
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Countries Visited: Italy, Corsica, Spain, Morocco (+1 more), Portugal
Super Earlybird
INSIDE
-
OCEANVIEW
$12,238
BALCONY
-
SUITE
$16,644
Save (per person) 2,607
From (per person) 12,238
View Trip
15 Day Traversing The Mediterranean: Lisbon Overnight with Holland America
Cruise
 (2)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 29 June 2025
Countries Visited: Italy, Sicily, Greece, Malta (+5 more), Tunisia, Sardinia, Spain, Morocco, Portugal
Exclusive Deal
INSIDE
$3,434
OCEANVIEW
$3,929
BALCONY
$4,424
SUITE
$6,701
From (per person) 3,434
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (3)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Countries Visited: Italy, Spain, Morocco, Portugal
INSIDE
$5,555
OCEANVIEW
$6,377
BALCONY
$8,337
SUITE
$12,930
From (per person) 5,555
View Trip
21 Day Empires & Explorers with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Monaco, France, Spain, Portugal, Morocco
Exclusive Deal
INSIDE
$7,994
OCEANVIEW
$8,450
BALCONY
$13,410
SUITE
$18,073
Save (per person) 2,056
From (per person) 7,994
View Trip
11 Day Western Mediterranean: Idyllic Isles & Hidden Gems with Holland America
Cruise
 (2)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 May 2026
Countries Visited: Italy, Sicily, Sardinia, Spain (+2 more), Gibraltar, Portugal
Exclusive Deal
INSIDE
$2,728
OCEANVIEW
$2,976
BALCONY
$4,015
SUITE
$5,550
From (per person) 2,728
View Trip
11 Day Mediterranean Icons Voyage with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 May 2025
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
INSIDE
$3,574
OCEANVIEW
$4,010
BALCONY
$5,455
SUITE
$8,910
From (per person) 3,574
View Trip
13 Day Spring Med & Grand Prix Voyage with Azamara Cruises
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 20 May 2025
Countries Visited: Italy, Corsica, France, Spain (+2 more), Gibraltar, Portugal
INSIDE
$4,626
OCEANVIEW
$4,923
BALCONY
$5,339
SUITE
$10,319
From (per person) 4,626
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (1)

20 Days (19 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain (+3 more), Gibraltar, Morocco, Portugal
Exclusive Deal
INSIDE
$7,550
OCEANVIEW
$8,303
BALCONY
$12,362
SUITE
$17,322
Save (per person) 2,050
From (per person) 7,550
View Trip
15 Day Italy, French Riviera & Spain Collectors' Voyage with Holland America
Cruise
 (2)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 26 July 2026
Countries Visited: Italy, France, Gibraltar, Spain (+2 more), Morocco, Portugal
Exclusive Deal
INSIDE
$3,582
OCEANVIEW
$4,176
BALCONY
-
SUITE
-
From (per person) 3,582
View Trip
11 Day Tuscan Summer with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 July 2026
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
Upgrade Your HorizonExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,876
SUITE
$13,608
Save (per person) 6,314
From (per person) 12,876
View Trip
21 Day Spain, Portugal & Mediterranean Jewels with Seabourn
Cruise

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Sojourn
Departure: 15 November 2026
Countries Visited: Italy, Corsica, Sardinia, Sicily (+6 more), Malta, Tunisia, Spain, Gibraltar, Morocco, Portugal
Sail Of The Year
INSIDE
-
OCEANVIEW
$11,886
BALCONY
$13,653
SUITE
$26,108
From (per person) 11,886
View Trip
13 Day Rome to Lisbon with Silversea
Cruise

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 November 2025
Countries Visited: Italy, Monaco, France, Spain (+1 more), Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,791
Save (per person) 2,609
From (per person) 10,791
View Trip
21 Day Rome to Lisbon with Silversea
Cruise

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Sardinia, Spain, Gibraltar, Morocco, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$18,216
BALCONY
$20,889
SUITE
$29,601
From (per person) 18,216
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Countries Visited: Italy, Malta, Sicily, Tunisia (+3 more), Sardinia, Spain, Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,098
BALCONY
$11,088
SUITE
$17,523
Save (per person) 4,102
From (per person) 10,098
View Trip
11 Day Rome to Lisbon with Silversea
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 17 May 2025
Countries Visited: Italy, France, Spain, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$7,078
BALCONY
$9,058
SUITE
$8,464
From (per person) 7,078
View Trip
18 Day Andalusian Nights & Barcelona Open with Seabourn
Cruise

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 13 April 2025
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
Sail Of The Year
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,400
From (per person) 13,400
View Trip
15 Day Rivieras, Minarets & More with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 28 April 2026
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
Exclusive Deal
INSIDE
$7,165
OCEANVIEW
$8,661
BALCONY
$9,733
SUITE
$14,022
Save (per person) 2,435
From (per person) 7,165
View Trip
17 Day Rome to Lisbon with Silversea
Cruise

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+4 more), Spain, Gibraltar, Morocco, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$15,147
From (per person) 15,147
View Trip
10 Day Spain's Southern Coast & Riviera Gems with Seabourn
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ships: Seabourn Encore, Seabourn Quest
Departures: Nov 2025 to Nov 2026
Countries Visited: Italy, Corsica, Sardinia, Spain (+1 more), Portugal
Sail Of The Year
INSIDE
-
OCEANVIEW
$6,068
BALCONY
$5,647
SUITE
$12,126
From (per person) 5,647
View Trip
15 Day Fado & Fun In Lisbon with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 May 2025
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$19,681
Save (per person) 10,269
From (per person) 19,681
View Trip
10 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sky
Departure: 14 October 2025
Countries Visited: Italy, France, Spain, Portugal
Exclusive Solo Offer
INSIDE
$3,353
OCEANVIEW
$3,953
BALCONY
$6,214
SUITE
$11,280
From (per person) 3,353
View Trip
10 Day Europe - Adriatic, Greece & Turkey - Venice with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sky
Departure: 25 June 2025
Countries Visited: Italy, France, Spain, Portugal
INSIDE
$3,812
OCEANVIEW
$4,836
BALCONY
$7,436
SUITE
$14,109
From (per person) 3,812
View Trip
Results: 24 results

No Results found. Try changing your search filters.




Cruises found! Scroll up to view

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Black Sea Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Food & Wine Cruises Luxury Cruises Short Cruise Breaks

Countries

Albania Corsica Croatia Cyprus England France Gibraltar Italy Malta Mexico Monaco Montenegro Morocco Portugal Sardinia Sicily Spain Tunisia Turkey USA

Cities

Rome

Routes

Cruises from Rome to Lisbon

Country Routes

Cruises from Italy to Portugal

Cruise Lines Exploring The Med

Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises P&O (UK) Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2025. Global Journeys. You're viewing our site in Australian dollars.

    

About Us | View Your Booking | Terms & Conditions | Site Map

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (AITA). No. A11351.

Travel Industry Associations