Home > Cruises > Central America Cruises > Panama > April 2026

Panama Cruises Starting In April 2026

If you're looking at joining a cruise to Panama in April 2026, we have 1 unique cruise itineraries and 1 departures available, operated by one of the world's leading cruise lines departing in April.

Filter Results

Departures (April 2026)

< March 2026

Price

Countries

Filter Results

1 Cruises (1 Cruise Departures)

Cruise

Southern Caribbean Cruise

2 Days (1 Nights) Colon to Cartagena

Cruise Line: Royal Caribbean

Ship: Serenade of the Seas

Departure: 18 April 2026

Countries Visited: Panama, Colombia

INSIDE

$223

OCEANVIEW

$298

BALCONY

$371

SUITE

$519

Save (per person) 76

From (per person) 223

View Trip

Results: 1 results

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

Luxury Cruises

Departure Months

January 2025 February 2025 March 2025 May 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 October 2026

Cities

Colon Panama City Santiago

Routes

Colon to Colon Miami to Panama City Panama City to Miami

Country Routes

Panama to USA USA to Panama

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Ponant Central America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking Central America Cruises Viking South America Cruises

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours