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Panama Tours & Cruises Starting In May 2026

If you're looking at joining a tour to Panama in May 2026, we have 5 unique cruises, small group tours and adventures with 89 departures from the world's leading tour operators departing in May.
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Departures (May 2026)
< April 2026 June 2026 >
Duration
15 Days
28 Days
Types
Budget
Start & End Cities
Operators
Price
$200pp
$257,000pp
Countries
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5 Trips (89 Trip Departures)
21 Day Seattle to Miami with Silversea
Cruise

21 Days (20 Nights) Seattle to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 11 May 2026
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Colombia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,415
Save (per person) 4,085
From (per person) 8,415
View Trip
15 Day Grand World Voyage with Holland America
Cruise

15 Days (14 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 03 May 2026
Countries Visited: USA, Mexico, El Salvador, Panama (+1 more), Colombia
Exclusive Deal
INSIDE
$5,652
OCEANVIEW
$6,087
BALCONY
$10,265
SUITE
-
From (per person) 5,652
View Trip
20 Day Panama Canal Passage with Seabourn
Cruise

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Ships: Seabourn Encore, Seabourn Quest, Seabourn Sojourn
Departures: Apr 2025 to May 2026
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Colombia
Sail Of The Year
INSIDE
-
OCEANVIEW
$10,634
BALCONY
$11,306
SUITE
$20,057
From (per person) 10,634
View Trip
28 Day Amazing Central America with Intrepid Travel
Tour

28 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Feb 2025 to Dec 2026
Trip Styles: Adventure, Small Group
Countries Visited: Guatemala, Honduras, El Salvador, Nicaragua (+2 more), Costa Rica, Panama
Big Sale
Save (per person) 1,400
From (per person) 4,447
View Trip
25 Day Panama Canal Passage with Seabourn
Cruise

25 Days (24 Nights) Vancouver to Miami
Cruise Line: Seabourn
Ship: Seabourn Sojourn
Departure: 15 May 2026
Countries Visited: Canada, USA, Mexico, Guatemala (+3 more), Costa Rica, Panama, Colombia
Sail Of The Year
INSIDE
-
OCEANVIEW
$11,905
BALCONY
$14,514
SUITE
$23,013
From (per person) 11,905
View Trip
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