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Panama Tours & Cruises Starting In September 2026

If you're looking at joining a tour to Panama in September 2026, we have 15 unique cruises, small group tours and adventures with 178 departures from the world's leading tour operators departing in September.
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Departures (September 2026)
< August 2026 October 2026 >
Duration
8 Days
41 Days
Types
Budget
Start & End Cities
Operators
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Price
$100pp
$214,598pp
Countries
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15 Trips (178 Trip Departures)
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Jewel of the Seas, Serenade of the Seas
Departures: Oct 2025 to Apr 2027
Countries Visited: Panama, Colombia, Aruba, Curacao
Latest Offer
INSIDE
$824
OCEANVIEW
$853
BALCONY
$974
SUITE
$1,266
Save (per person) 747
From (per person) 824
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Jewel of the Seas, Serenade of the Seas
Departures: Oct 2025 to Apr 2027
Countries Visited: Colombia, Aruba, Curacao, Panama
Latest Offer
INSIDE
$881
OCEANVIEW
$921
BALCONY
$1,041
SUITE
$1,353
Save (per person) 842
From (per person) 881
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (2)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Oct 2025 to Apr 2027
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Aruba
Exclusive DealSpring Swing Offer
INSIDE
$1,179
OCEANVIEW
$1,327
BALCONY
$2,006
SUITE
$2,713
From (per person) 1,179
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Jewel of the Seas, Serenade of the Seas
Departures: Dec 2025 to Sep 2026
Countries Visited: Colombia, Bonaire, Aruba, Curacao (+1 more), Panama
Latest OfferExclusive Solo Offer
INSIDE
$893
OCEANVIEW
$933
BALCONY
$1,053
SUITE
$1,365
Save (per person) 825
From (per person) 893
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise

24 Days (23 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 27 September 2026
Countries Visited: Canada, USA, Mexico, Panama (+1 more), Aruba
Exclusive DealSpring Swing Offer
INSIDE
$2,882
OCEANVIEW
$3,777
BALCONY
$5,271
SUITE
$8,736
From (per person) 2,882
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 05 September 2026
Countries Visited: Panama, Colombia, Bonaire, Aruba (+1 more), Curacao
Latest Offer
INSIDE
$892
OCEANVIEW
$929
BALCONY
$1,045
SUITE
$1,397
Save (per person) 469
From (per person) 892
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Colombia
Escape To Sea
INSIDE
$1,799
OCEANVIEW
$2,019
BALCONY
$2,479
SUITE
$4,719
From (per person) 1,799
View Trip
28 Day Amazing Central America with Intrepid Travel
Tour

28 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Apr 2025 to Dec 2026
Trip Styles: Adventure, Small Group
Countries Visited: Guatemala, Honduras, El Salvador, Nicaragua (+2 more), Costa Rica, Panama
Exclusive Deal
Save (per person) 423
From (per person) 3,807
View Trip
22 Day Seattle To Miami with Cunard
Cruise
 (12)

22 Days (21 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2026
Countries Visited: USA, Mexico, Guatemala, Panama (+2 more), Curacao, Aruba
Exclusive Deal
INSIDE
$4,259
OCEANVIEW
$4,709
BALCONY
$5,459
SUITE
$14,259
From (per person) 4,259
View Trip
23 Day Panama Canal & Pacific Coast with Princess
Cruise
 (2)

23 Days (22 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Coral Princess
Departure: 23 September 2026
Countries Visited: Canada, USA, Mexico, Costa Rica (+2 more), Panama, Aruba
Exclusive DealSpring Swing Offer
INSIDE
-
OCEANVIEW
$2,362
BALCONY
$3,550
SUITE
$4,807
From (per person) 2,362
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise

25 Days (24 Nights) Seattle to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 September 2026
Countries Visited: USA, Mexico, Costa Rica, Panama (+3 more), Colombia, Cayman Islands, Jamaica
Escape To Sea
INSIDE
$2,148
OCEANVIEW
$2,438
BALCONY
$3,218
SUITE
-
From (per person) 2,148
View Trip
29 Day Seattle To Miami with Cunard
Cruise
 (12)

29 Days (28 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2026
Countries Visited: USA, Canada, Mexico, Guatemala (+3 more), Panama, Curacao, Aruba
Exclusive Deal
INSIDE
$4,929
OCEANVIEW
$5,429
BALCONY
$6,379
SUITE
$16,479
From (per person) 4,929
View Trip
22 Day Panama Canal with Holland America
Cruise
 (1)

22 Days (21 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 27 September 2026
Countries Visited: Canada, USA, Mexico, Guatemala (+4 more), El Salvador, Panama, Colombia, Bahamas
Exclusive Deal
INSIDE
$3,203
OCEANVIEW
$3,599
BALCONY
$4,589
SUITE
$6,965
From (per person) 3,203
View Trip
34 Day Seattle To Miami with Cunard
Cruise
 (12)

34 Days (33 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2026
Countries Visited: USA, Mexico, Guatemala, Panama (+8 more), Curacao, Aruba, Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados, Saint Martin, Virgin Islands
Exclusive Deal
INSIDE
$5,739
OCEANVIEW
$6,439
BALCONY
$7,639
SUITE
$20,439
From (per person) 5,739
View Trip
41 Day Seattle To Miami with Cunard
Cruise
 (12)

41 Days (40 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2026
Countries Visited: USA, Canada, Mexico, Guatemala (+9 more), Panama, Curacao, Aruba, Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados, Saint Martin, Virgin Islands
Exclusive Deal
INSIDE
$6,659
OCEANVIEW
$7,459
BALCONY
$8,859
SUITE
$23,959
From (per person) 6,659
View Trip
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