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Cruises from Santiago to Buenos Aires

Are you looking for a cruise from Santiago to Buenos Aires? February and November are the most popular months to cruise between Santiago and Buenos Aires and there are 28 departures available from eight of the world's leading cruise lines.
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13 Days
31 Days
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$3,400pp
$79,110pp
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16 Cruises (28 Cruise Departures)
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (4)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Feb 2025 to Feb 2027
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$10,775
SUITE
$19,791
Save (per person) 356
From (per person) 10,775
View Trip
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
Cruise
 (1)

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2025 to Nov 2026
Countries Visited: Chile, Argentina
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$12,568
SUITE
$17,815
Save (per person) 2,427
From (per person) 12,568
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 December 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$3,552
OCEANVIEW
$3,938
BALCONY
$5,384
SUITE
$6,869
From (per person) 3,552
View Trip
15 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 23 February 2027
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$3,457
OCEANVIEW
$3,853
BALCONY
$5,289
SUITE
$6,972
From (per person) 3,457
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Eclipse II
Departures: Feb 2026 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Antarctica, Argentina
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$51,660
SUITE
$61,622
Save (per person) 5,499
From (per person) 51,660
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$18,793
SUITE
$19,387
Save (per person) 6,967
From (per person) 18,793
View Trip
31 Day Chilean Fjords, Glaciers & Antarctic Wildlife Explorer with Scenic
Cruise

31 Days (30 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Countries Visited: Chile, Argentina, Falkland Islands, South Georgia Island (+1 more), Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$63,025
SUITE
$79,449
Save (per person) 16,085
From (per person) 63,025
View Trip
20 Day Ushuaia & The White Continent with Regent Seven Seas
Cruise

20 Days (19 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 February 2025
Countries Visited: Chile, Argentina, Antarctica, Falkland Islands (+1 more), Uruguay
Exclusive DealUpgrade Your Horizon
INSIDE
-
OCEANVIEW
-
BALCONY
$20,864
SUITE
$21,597
Save (per person) 8,036
From (per person) 20,864
View Trip
22 Day Puerto Williams to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Santiago to Buenos Aires
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 10 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$37,125
Save (per person) 2,875
From (per person) 37,125
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 14 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$26,460
SUITE
$27,499
Save (per person) 2,635
From (per person) 26,460
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Countries Visited: Chile, Argentina
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$22,124
SUITE
$28,064
Save (per person) 6,691
From (per person) 22,124
View Trip
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$58,013
SUITE
$65,438
Save (per person) 7,052
From (per person) 58,013
View Trip
22 Day Puerto Williams to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Santiago to Buenos Aires
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 04 March 2027
Countries Visited: Chile, Antarctica, South Georgia Island, Falkland Islands (+1 more), Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$32,472
Save (per person) 4,328
From (per person) 32,472
View Trip
24 Day Antarctica & Falklands - From Punta Arenas To Buenos Aires with HX Hurtigruten Expeditions
Cruise

24 Days (23 Nights) Santiago to Buenos Aires
Ship: MS Fram
Departure: 20 March 2026
Countries Visited: Chile, Antarctica, Falkland Islands, Argentina
Wave Offer
INSIDE
-
OCEANVIEW
$23,648
BALCONY
-
SUITE
$31,628
Save (per person) 5,862
From (per person) 23,648
View Trip
15 Day Cape Horn & Strait of Magellan with Princess
Cruise

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 21 February 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$4,423
OCEANVIEW
$4,620
BALCONY
$7,136
SUITE
$8,086
From (per person) 4,423
View Trip
17 Day Cape Horn & Strait of Magellan with Princess
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 06 December 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$5,211
OCEANVIEW
$5,257
BALCONY
$7,633
SUITE
$9,200
From (per person) 5,211
View Trip
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