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Spain Cruises Starting In May 2025

If you're looking at joining a cruise to Spain in May 2025, we have 55 unique cruise itineraries and 421 departures available, operated by fifteen of the world's leading cruise lines departing in May.
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Departures (May 2025)
< April 2025 June 2025 >
Duration
4 Days
16 Days
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$200pp
$33,280pp
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55 Cruises (421 Cruise Departures)
6 Day Grand Prix Voyage with Azamara Cruises
Cruise
 (1)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 22 May 2025
Countries Visited: Spain, France
INSIDE
$2,977
OCEANVIEW
$3,194
BALCONY
$3,194
SUITE
$5,452
From (per person) 2,977
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 07 May 2025
Countries Visited: Spain, Italy
Early Booking Offer
INSIDE
$670
OCEANVIEW
$728
BALCONY
$806
SUITE
$1,330
From (per person) 670
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: May 2025 to Oct 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$1,601
OCEANVIEW
$1,751
BALCONY
$1,693
SUITE
$2,626
Save (per person) 1,201
From (per person) 1,601
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Harmony of the Seas
Departures: Apr 2025 to Jul 2026
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
$1,471
OCEANVIEW
$1,727
BALCONY
$1,696
SUITE
$2,640
Save (per person) 1,088
From (per person) 1,471
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Harmony of the Seas
Departures: Apr 2025 to Jun 2026
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$1,518
OCEANVIEW
$1,745
BALCONY
$1,839
SUITE
$2,609
Save (per person) 1,083
From (per person) 1,518
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2025 to Oct 2025
Countries Visited: Italy, Spain, France
Seasational SaleBlack Friday Cruise Only
INSIDE
$1,570
OCEANVIEW
$1,667
BALCONY
$1,929
SUITE
$2,598
From (per person) 1,570
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Feb 2025 to Sep 2026
Countries Visited: Italy, Monaco, France, Spain
Limited Time Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$4,648
SUITE
$7,123
Save (per person) 992
From (per person) 4,648
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: May 2025 to Oct 2025
Countries Visited: Spain, Italy, France
Early Booking Offer
INSIDE
$1,279
OCEANVIEW
$1,522
BALCONY
$1,648
SUITE
$2,346
From (per person) 1,279
View Trip
7 Day Europe - Western Mediterranean - Rome with Norwegian Cruise Line
Cruise
 (1)

7 Days (6 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 08 May 2025
Countries Visited: Italy, Spain, France
INSIDE
$2,155
OCEANVIEW
-
BALCONY
$2,615
SUITE
$2,966
From (per person) 2,155
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Italy
Seasational SaleBlack Friday Cruise Only
INSIDE
$1,522
OCEANVIEW
$1,716
BALCONY
$1,910
SUITE
$2,598
From (per person) 1,522
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Cannes to Cannes
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2025 to Oct 2025
Countries Visited: France, Italy, Spain
Seasational Sale
INSIDE
$1,473
OCEANVIEW
$1,667
BALCONY
$1,910
SUITE
$2,647
From (per person) 1,473
View Trip
8 Day Mediterranean Spring with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 06 May 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
$3,961
OCEANVIEW
-
BALCONY
-
SUITE
-
Save (per person) 2,029
From (per person) 3,961
View Trip
12 Day The Iberian Peninsula and Fortified Cities of the Atlantic with Ponant
Cruise
 (1)

12 Days (11 Nights) Lisbon to Honfleur
Cruise Line: Ponant
Ship: Le Boreal
Departure: 03 May 2025
Countries Visited: Portugal, Spain, France
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
$8,062
BALCONY
$8,728
SUITE
$14,922
Save (per person) 148
From (per person) 8,062
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2025 to Oct 2025
Countries Visited: Italy, Spain, France
Seasational Sale
INSIDE
$1,493
OCEANVIEW
$1,716
BALCONY
$1,949
SUITE
$2,647
From (per person) 1,493
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

15 Days (14 Nights) London to London
Cruise Line: P&O Cruises Worldwide
Ships: Britannia, Ventura
Departures: Apr 2025 to Oct 2026
Countries Visited: England, Portugal, Spain
Latest Offer
INSIDE
$2,250
OCEANVIEW
$2,693
BALCONY
$3,027
SUITE
$5,631
From (per person) 2,250
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 06 May 2025
Countries Visited: Italy, Spain, France
Seasational Sale
INSIDE
$1,561
OCEANVIEW
$1,707
BALCONY
$1,891
SUITE
$2,667
From (per person) 1,561
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Barcelona to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 04 May 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$1,561
SUITE
$1,842
From (per person) 1,561
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 04 May 2025
Countries Visited: Spain, France, Italy
Black Friday Cruise OnlySeasational Sale
INSIDE
$1,289
OCEANVIEW
$1,406
BALCONY
$1,561
SUITE
$2,618
From (per person) 1,289
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Italy
Seasational Sale
INSIDE
$1,493
OCEANVIEW
$1,716
BALCONY
$1,910
SUITE
$2,647
From (per person) 1,493
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Marseille to Cannes
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 05 May 2025
Countries Visited: France, Italy, Spain
Seasational Sale
INSIDE
$1,513
OCEANVIEW
$1,658
BALCONY
$1,842
SUITE
$2,618
From (per person) 1,513
View Trip
8 Day Barcelona to Rome & More with Virgin Voyages
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 25 May 2025
Countries Visited: Spain, Italy, Corsica
INSIDE
$1,941
OCEANVIEW
$2,266
BALCONY
$2,592
SUITE
$6,092
From (per person) 1,941
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: May 2025 to Oct 2025
Countries Visited: France, Spain, Italy
Early Booking Offer
INSIDE
$1,279
OCEANVIEW
$1,522
BALCONY
$1,648
SUITE
$2,511
From (per person) 1,279
View Trip
9 Day Mediterranean with MSC Cruises
Cruise

9 Days (8 Nights) Genoa to Rome
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 05 May 2025
Countries Visited: Italy, France, Spain
Early Booking Offer
INSIDE
$1,153
OCEANVIEW
$1,338
BALCONY
$1,483
SUITE
$2,259
From (per person) 1,153
View Trip
13 Day Barcelona to Rome with Silversea
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 May 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,662
Save (per person) 5,138
From (per person) 13,662
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: Apr 2025 to Oct 2025
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
$1,719
OCEANVIEW
$2,010
BALCONY
$2,124
SUITE
$2,969
Save (per person) 1,268
From (per person) 1,719
View Trip
10 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2025 to Sep 2026
Countries Visited: Spain, Portugal, Morocco
Exclusive DealBlack Friday Cyber Sale
INSIDE
$1,996
OCEANVIEW
$2,459
BALCONY
$2,885
SUITE
$8,184
Save (per person) 3,747
From (per person) 1,996
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: May 2025 to Sep 2025
Countries Visited: Italy, France, Spain
Early Booking Offer
INSIDE
$1,279
OCEANVIEW
$1,522
BALCONY
$1,648
SUITE
$2,346
From (per person) 1,279
View Trip
10 Day Wonders Of Spain with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 May 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,426
SUITE
$13,604
Save (per person) 10,514
From (per person) 12,426
View Trip
11 Day Spain And Portugal with P&O Cruises Worldwide
Cruise

11 Days (10 Nights) London to London
Cruise Line: P&O Cruises Worldwide
Ship: Ventura
Departures: May 2025 to Jun 2026
Countries Visited: England, Spain, Portugal
Latest Offer
INSIDE
$1,853
OCEANVIEW
$2,119
BALCONY
$2,554
SUITE
$4,812
From (per person) 1,853
View Trip
8 Day Western Europe with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) London to London
Cruise Line: P&O Cruises Worldwide
Ship: Ventura
Departures: May 2025 to Oct 2026
Countries Visited: England, Spain, France
Latest Offer
INSIDE
$1,120
OCEANVIEW
$1,357
BALCONY
$1,643
SUITE
$2,762
From (per person) 1,120
View Trip
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