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Italy Cruises Starting In April 2025

If you're looking at joining a cruise to Italy in April 2025, we have 62 unique cruise itineraries and 514 departures available, operated by sixteen of the world's leading cruise lines departing in April.
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Departures (April 2025)
< March 2025 May 2025 >
Duration
2 Days
16 Days
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$79pp
$38,980pp
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62 Cruises (514 Cruise Departures)
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 21 April 2025
Countries Visited: Italy, France
One Way Cruise Offer
INSIDE
$115
OCEANVIEW
$175
BALCONY
$235
SUITE
$505
From (per person) 115
View Trip
12 Day Venice and Croatian Islands Cruise with Collette
Tour + Cruise

12 Days Split to Venice or Venice to Split
Operated By: Collette
Departures: Apr 2025 to May 2026
Trip Styles: Coach, Cruise, Island Hopping, Scenic
Countries Visited: Croatia, Italy
From (per person) 3,999
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
One Way Cruise Offer
INSIDE
$181
OCEANVIEW
$241
BALCONY
$331
SUITE
$591
From (per person) 181
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 17 April 2025
Countries Visited: Italy, Spain
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
-
BALCONY
$976
SUITE
-
From (per person) 976
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 16 April 2025
Countries Visited: Italy, Spain
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
$821
BALCONY
$961
SUITE
$1,481
From (per person) 821
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 21 April 2025
Countries Visited: Italy, Spain
One Way Cruise Offer
INSIDE
$133
OCEANVIEW
$193
BALCONY
$253
SUITE
-
From (per person) 133
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Marseille to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2025
Countries Visited: France, Italy
One Way Cruise Offer
INSIDE
$255
OCEANVIEW
$315
BALCONY
$375
SUITE
-
From (per person) 255
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Magnifica (+2 more), MSC Musica, MSC Opera
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France
One Way Cruise Offer
INSIDE
$79
OCEANVIEW
$109
BALCONY
$159
SUITE
$309
From (per person) 79
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 21 April 2025
Countries Visited: France, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$190
OCEANVIEW
-
BALCONY
$280
SUITE
$510
From (per person) 190
View Trip
12 Day Venice and Croatian Islands Cruise with Collette
Tour + Cruise

12 Days Venice to Split or Split to Venice
Operated By: Collette
Departures: Apr 2025 to May 2026
Trip Styles: Coach, Cruise, Island Hopping, Scenic
Countries Visited: Italy, Croatia
Last Minute DealLatest Offer
Save (per person) 400
From (per person) 3,599
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Musica
Departures: Apr 2025 to Dec 2025
Countries Visited: Italy, France
One Way Cruise OfferEscape To Sea - Cruise Only
INSIDE
$177
OCEANVIEW
$210
BALCONY
$274
SUITE
$514
From (per person) 177
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Apr 2025 to Apr 2026
Countries Visited: Greece, Turkey, Italy
Escape To Sea - Cruise OnlyBook Early Offer + Onboard Credit
INSIDE
$517
OCEANVIEW
$707
BALCONY
$1,027
SUITE
$1,297
From (per person) 517
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 18 April 2025
Countries Visited: Spain, Italy, France
Escape To Sea - Cruise Only
INSIDE
$789
OCEANVIEW
$939
BALCONY
$1,089
SUITE
$1,729
From (per person) 789
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Izmir to Izmir
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Mar 2025 to Apr 2026
Countries Visited: Turkey, Greece, Italy
Escape To Sea - Cruise Only
INSIDE
$522
OCEANVIEW
$762
BALCONY
$1,032
SUITE
$1,302
From (per person) 522
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (7)

8 Days (7 Nights) Rome to Venice
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vesta
Departures: Apr 2025 to Jul 2027
Countries Visited: Italy, Sicily, Croatia
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$3,799
SUITE
$5,349
From (per person) 3,799
View Trip
12 Day Barcelona to Rome with Silversea
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 26 April 2025
Countries Visited: Spain, France, Monaco, Italy
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,450
From (per person) 7,450
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Apr 2025 to Nov 2025
Countries Visited: Spain, France, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$354
OCEANVIEW
$464
BALCONY
$514
SUITE
$784
From (per person) 354
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departures: Apr 2025 to Oct 2025
Countries Visited: Italy, Greece, Croatia
Escape To Sea - Cruise Only
INSIDE
$727
OCEANVIEW
$897
BALCONY
$1,357
SUITE
$1,551
From (per person) 727
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Apr 2025 to Apr 2025
Countries Visited: France, Spain, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$460
OCEANVIEW
$550
BALCONY
$590
SUITE
$940
From (per person) 460
View Trip
11 Day Flair, Flavor & Culture with Regent Seven Seas
Cruise

11 Days (10 Nights) Monte Carlo to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 April 2025
Countries Visited: Monaco, Italy, Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$18,198
SUITE
$11,899
Save (per person) 17,099
From (per person) 11,899
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 April 2025
Countries Visited: Italy, France, Spain
One Way Cruise Offer
INSIDE
-
OCEANVIEW
$315
BALCONY
$405
SUITE
-
From (per person) 315
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Rome to Venice
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 07 April 2025
Countries Visited: Italy, Greece, Croatia
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$1,149
From (per person) 1,149
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Genoa to Valletta
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 13 April 2025
Countries Visited: Italy, Sicily, Malta
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$1,460
From (per person) 1,460
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 20 April 2025
Countries Visited: Spain, France, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$461
OCEANVIEW
-
BALCONY
$591
SUITE
$941
From (per person) 461
View Trip
8 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (2)

8 Days (7 Nights) Rome to Athens
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Sep 2025
Countries Visited: Italy, Greece, Turkey
Exclusive DealSpring Swing Offer
INSIDE
$1,131
OCEANVIEW
$1,491
BALCONY
$1,963
SUITE
$2,113
From (per person) 1,131
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Amalfi to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 26 April 2025
Countries Visited: Italy, Greece, Turkey
One Way Cruise Offer
INSIDE
$514
OCEANVIEW
$634
BALCONY
$744
SUITE
$1,154
From (per person) 514
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Genoa to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 April 2025
Countries Visited: Italy, Greece, Turkey
One Way Cruise Offer
INSIDE
$476
OCEANVIEW
$626
BALCONY
$766
SUITE
$1,286
From (per person) 476
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 26 April 2025
Countries Visited: Italy, Sicily, Spain
One Way Cruise Offer
INSIDE
$429
OCEANVIEW
$539
BALCONY
$649
SUITE
$1,149
From (per person) 429
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Splendida
Departures: Apr 2025 to May 2025
Countries Visited: Italy, France, Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$1,429
OCEANVIEW
$1,557
BALCONY
$514
SUITE
$789
From (per person) 514
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 03 April 2025
Countries Visited: France, Spain, Italy
One Way Cruise Offer
INSIDE
$359
OCEANVIEW
$459
BALCONY
$719
SUITE
$879
From (per person) 359
View Trip
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