Italy Cruises Starting In April 2025

If you're looking at joining a cruise to Italy in April 2025, we have 70 unique cruise itineraries and 569 departures available, operated by eighteen of the world's leading cruise lines departing in April.
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Departures (April 2025)
Duration
2 Days
26 Days
Countries Visited
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Ship Size
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Price
$200pp
$53,820pp
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70 Cruises (569 Cruise Departures)
Cruise
 (1)

3 Days (2 Nights) Marseille to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2025
Countries Visited: France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$710
BALCONY
$760
SUITE
-
From (per person) 710
Cruise
 (1)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Departure: 16 April 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$1,042
OCEANVIEW
$1,220
BALCONY
$1,428
SUITE
$2,378
From (per person) 1,042
Cruise
 (1)

3 Days (2 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Departure: 16 April 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$512
BALCONY
$621
SUITE
$1,017
From (per person) 512
Cruise
 (1)

6 Days (5 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Departure: 17 April 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$1,270
OCEANVIEW
-
BALCONY
$1,735
SUITE
-
From (per person) 1,270
Tour + Cruise

12 Days Split to Venice or Venice to Split
Operated By: Collette
Departures: Apr 2025 to May 2026
Trip Styles: Coach, Cruise, Island Hopping, Scenic
Countries Visited: Croatia, Italy
Exclusive Savings
From (per person) 5,890
Cruise

3 Days (2 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Departures: Apr 2025 to Dec 2025
Countries Visited: Italy, France
Exclusive DealEarly Booking Offer
INSIDE
$275
OCEANVIEW
$354
BALCONY
$403
SUITE
$839
From (per person) 275
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Departures: Apr 2025 to Jul 2026
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
$1,329
OCEANVIEW
$1,709
BALCONY
$1,704
SUITE
$2,524
Save (per person) 1,112
From (per person) 1,329
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France
Exclusive Deal
INSIDE
$267
OCEANVIEW
$316
BALCONY
$395
SUITE
$643
From (per person) 267
Cruise

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Departures: Apr 2025 to Nov 2025
Countries Visited: France, Italy
Exclusive DealEarly Booking Offer
INSIDE
$285
OCEANVIEW
$374
BALCONY
$433
SUITE
$760
From (per person) 285
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Departures: Apr 2025 to Jun 2026
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$1,441
OCEANVIEW
$1,655
BALCONY
$1,714
SUITE
$3,320
Save (per person) 1,358
From (per person) 1,441
Cruise
 (2)

8 Days (7 Nights) Rome to Athens
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Sep 2025
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
$2,167
OCEANVIEW
$2,945
BALCONY
$3,410
SUITE
$3,866
From (per person) 2,167
Tour + Cruise
 (5)

26 Days Milan to Dubrovnik
Operated By: Bunnik Tours
Departures: Apr 2025 to Aug 2025
Countries Visited: Italy, Slovenia, Croatia
Exclusive Savings
Save (per person) 357
From (per person) 17,648
Cruise
 (1)

7 Days (6 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Departure: 18 April 2025
Countries Visited: Spain, Italy, France
Exclusive Deal
INSIDE
$1,446
OCEANVIEW
$1,654
BALCONY
$1,902
SUITE
-
From (per person) 1,446
Cruise
 (1)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Departures: Apr 2025 to May 2026
Countries Visited: Turkey, Greece, Italy
Exclusive Deal
INSIDE
$530
OCEANVIEW
$560
BALCONY
$738
SUITE
$995
From (per person) 530
Cruise
 (3)

8 Days (7 Nights) London to Rome
Cruise Line: Cunard
Ship: Queen Mary 2
Departure: 13 April 2025
Countries Visited: England, Spain, Italy
Exclusive Deal
INSIDE
$2,368
OCEANVIEW
-
BALCONY
$3,387
SUITE
$6,427
From (per person) 2,368
Cruise
 (1)

7 Days (6 Nights) Genoa to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 April 2025
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
$1,318
BALCONY
$1,536
SUITE
$2,328
From (per person) 1,318
Cruise
 (1)

9 Days (8 Nights) Venice to Venice
Cruise Line: Azamara Cruises
Departure: 23 April 2025
Countries Visited: Italy, Croatia, Montenegro
INSIDE
$3,614
OCEANVIEW
$3,841
BALCONY
-
SUITE
-
From (per person) 3,614
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Departures: Apr 2025 to Nov 2025
Countries Visited: Spain, France, Italy
Exclusive DealSave And Sail Offer
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,221
From (per person) 608
Cruise
 (1)

6 Days (5 Nights) Amalfi to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 26 April 2025
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$1,299
SUITE
$1,923
From (per person) 1,299
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Departures: Apr 2025 to Nov 2025
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,221
From (per person) 608
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Departure: 26 April 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,761
SUITE
$14,818
Save (per person) 189
From (per person) 9,761
Cruise
 (2)

4 Days (3 Nights) Genoa to Valletta
Cruise Line: MSC Cruises
Departure: 13 April 2025
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$2,380
From (per person) 2,380
Cruise
 (1)

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2025 to Apr 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$679
SUITE
$1,471
From (per person) 679
Cruise
 (1)

6 Days (5 Nights) Genoa to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 21 April 2025
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$1,388
SUITE
-
From (per person) 1,388
Cruise
 (1)

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2025 to Apr 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$413
OCEANVIEW
-
BALCONY
$571
SUITE
$1,415
From (per person) 413
Cruise
 (1)

13 Days (12 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Departure: 11 April 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$4,764
OCEANVIEW
$5,071
BALCONY
-
SUITE
$10,486
From (per person) 4,764
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Departures: Apr 2025 to Nov 2025
Countries Visited: France, Italy, Spain
Exclusive Deal
INSIDE
$608
OCEANVIEW
$736
BALCONY
$806
SUITE
$1,320
From (per person) 608
Cruise
 (1)

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 April 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$857
SUITE
-
From (per person) 857
Cruise

18 Days (17 Nights) Monte Carlo to Istanbul
Cruise Line: Regent Seven Seas
Departure: 20 April 2025
Countries Visited: Monaco, Italy, Turkey, Greece
Upgrade Your HorizonExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,426
SUITE
$20,416
Save (per person) 9,344
From (per person) 16,426
Tour + Cruise

16 Days Venice to Athens
Operated By: Cosmos
Departures: May 2025 to Sep 2025
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
Save (per person) 217
From (per person) 6,539
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