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Med Cruises Starting In September 2025

If you're looking at joining a cruise sailing in and around the Mediterranean in September 2025, we have 168 unique cruises with 2,674 departures from the world's leading cruise lines departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
5 Days
36 Days
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$78pp
$48,798pp
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168 Cruises (2,674 Cruise Departures)
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Barcelona
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jul 2025 to Sep 2027
Countries Visited: Italy, Monaco, France, Spain
INSIDE
-
OCEANVIEW
-
BALCONY
$2,799
SUITE
$5,049
From (per person) 2,799
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2025 to Oct 2026
Countries Visited: Spain, France, Italy, Sicily (+1 more), Malta
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$937
OCEANVIEW
$1,155
BALCONY
$1,333
SUITE
$1,966
From (per person) 937
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Italy, France, Spain, Portugal (+1 more), Sardinia
Escape To Sea - Cruise Only
INSIDE
$1,250
OCEANVIEW
$1,359
BALCONY
$1,686
SUITE
$2,631
From (per person) 1,250
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: May 2025 to Oct 2026
Countries Visited: Italy, Spain, France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$892
OCEANVIEW
$916
BALCONY
$1,153
SUITE
$1,638
From (per person) 892
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: May 2025 to Oct 2026
Countries Visited: Spain, Italy, France
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$851
OCEANVIEW
$895
BALCONY
$1,034
SUITE
$2,455
From (per person) 851
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: May 2025 to Oct 2026
Countries Visited: Spain, France, Italy
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$900
OCEANVIEW
$1,108
BALCONY
$1,167
SUITE
$1,732
From (per person) 900
View Trip
11 Day Wine Lovers Dream with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 13 September 2025
Countries Visited: Spain, France, Italy, Sicily (+2 more), Turkey, Greece
Upgrade Your HorizonExclusive Deal
INSIDE
-
OCEANVIEW
$9,899
BALCONY
$9,899
SUITE
$11,899
Save (per person) 9,899
From (per person) 9,899
View Trip
29 Day Mediterranean's Iconic Shores with Viking Cruises
Cruise
 (5)

29 Days (28 Nights) Barcelona to Istanbul
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+6 more), Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vesta
Departures: Jul 2025 to Jul 2027
Countries Visited: Spain, France, Monaco, Italy (+5 more), Sicily, Croatia, Montenegro, Greece, Turkey
INSIDE
-
OCEANVIEW
-
BALCONY
$13,796
SUITE
$20,396
From (per person) 13,796
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2025 to Nov 2026
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$968
OCEANVIEW
$1,201
BALCONY
$1,379
SUITE
$2,013
From (per person) 968
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Tarragona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 20 September 2025
Countries Visited: Spain, France, Italy, Sicily (+1 more), Malta
Escape To Sea - Cruise Only
INSIDE
-
OCEANVIEW
-
BALCONY
$945
SUITE
$1,519
From (per person) 945
View Trip
21 Day Tyrrhenian Treasures & Mediterranean Jewels with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 September 2025
Countries Visited: Spain, Sardinia, Corsica, Italy (+4 more), France, Monaco, Sicily, Malta
Sail Of The Year Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$11,899
SUITE
$22,014
From (per person) 11,899
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2025 to Nov 2025
Countries Visited: France, Spain, Sardinia, Italy
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$701
OCEANVIEW
$850
BALCONY
$968
SUITE
$1,750
From (per person) 701
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Spain, Sardinia, Italy, France (+1 more), Portugal
Escape To Sea - Cruise Only
INSIDE
$1,194
OCEANVIEW
$1,333
BALCONY
-
SUITE
$2,619
From (per person) 1,194
View Trip
22 Day The Best of the Mediterranean with Princess
Cruise
 (2)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 20 September 2025
Countries Visited: Spain, Gibraltar, France, Italy (+4 more), Sicily, Greece, Turkey, Montenegro
Exclusive Deal
INSIDE
$4,746
OCEANVIEW
$5,506
BALCONY
$5,896
SUITE
$6,976
From (per person) 4,746
View Trip
11 Day Flamenco & Jaleo with Regent Seven Seas
Cruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 14 September 2025
Countries Visited: Portugal, Spain, France
Exclusive DealUpgrade Your Horizon
INSIDE
-
OCEANVIEW
-
BALCONY
$7,299
SUITE
$10,999
Save (per person) 13,699
From (per person) 7,299
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2025 to Oct 2026
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$999
OCEANVIEW
$1,223
BALCONY
$1,343
SUITE
$2,035
From (per person) 999
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Seaside
Departures: May 2025 to Oct 2026
Countries Visited: Sicily, Italy, France, Spain (+1 more), Tunisia
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$872
OCEANVIEW
$1,080
BALCONY
$1,056
SUITE
$1,541
From (per person) 872
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Splendida
Departures: May 2025 to Oct 2026
Countries Visited: Spain, France, Italy, Sicily (+1 more), Malta
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$812
OCEANVIEW
$931
BALCONY
$881
SUITE
$1,456
From (per person) 812
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Cagliari to Cagliari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2025 to Nov 2025
Countries Visited: Sardinia, Italy, France, Spain
Escape To Sea - Cruise Only
INSIDE
$727
OCEANVIEW
$851
BALCONY
$1,088
SUITE
-
From (per person) 727
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Countries Visited: Malta, Sicily, Italy
Complimentary Hotel Night
From (per person) 12,490
View Trip
8 Day A Journey of Limoncello Days & Sardinian Sunsets with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Aug 2025 to Sep 2025
Countries Visited: Italy, Sicily, Sardinia, Spain
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$4,815
SUITE
$5,535
From (per person) 4,815
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Seaside
Departures: Apr 2025 to Oct 2026
Countries Visited: Spain, Tunisia, Sicily, Italy (+1 more), France
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$881
OCEANVIEW
$1,089
BALCONY
$1,103
SUITE
$1,588
From (per person) 881
View Trip
15 Day Eastern Mediterranean: Egypt & Istanbul Overnight with Holland America
Cruise
 (2)

15 Days (14 Nights) Barcelona to Athens
Cruise Line: Holland America
Ship: Nieuw Statendam
Departure: 20 September 2025
Countries Visited: Spain, Malta, Egypt, Cyprus (+2 more), Greece, Turkey
Exclusive Deal
INSIDE
$2,059
OCEANVIEW
$2,659
BALCONY
$2,659
SUITE
$3,959
From (per person) 2,059
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2025 to Nov 2025
Countries Visited: Italy, France, Spain, Sardinia
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$693
OCEANVIEW
$842
BALCONY
$1,044
SUITE
$1,743
From (per person) 693
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2025 to Oct 2026
Countries Visited: France, Italy, Sicily, Malta (+1 more), Spain
Escape To Sea - Cruise OnlyDrinks and Wi-Fi Included
INSIDE
$901
OCEANVIEW
$1,154
BALCONY
$1,332
SUITE
$1,965
From (per person) 901
View Trip
8 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (2)

8 Days (7 Nights) Naples to Athens
Cruise Line: Princess
Ship: Sun Princess
Departure: 27 September 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
$1,596
OCEANVIEW
$2,026
BALCONY
$2,246
SUITE
$2,696
From (per person) 1,596
View Trip
15 Day An Extended Journey To Modernist Masterpieces And Sunny Shores with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Sardinia, Spain (+1 more), France
Explora Extended Journey SavingUnique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$10,400
SUITE
$12,015
From (per person) 10,400
View Trip
7 Day Corsican Shores, Under Sail Aboard Le Ponant with Ponant
Cruise

7 Days (6 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 27 September 2025
Countries Visited: France, Corsica
INSIDE
-
OCEANVIEW
$12,620
BALCONY
$16,180
SUITE
$17,360
From (per person) 12,620
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Harmony of the Seas
Departures: May 2025 to Aug 2026
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
$878
OCEANVIEW
$1,131
BALCONY
$1,133
SUITE
$1,968
Save (per person) 966
From (per person) 878
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Messina to Messina
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2025 to Oct 2026
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Drinks and Wi-Fi IncludedEscape To Sea - Cruise Only
INSIDE
$937
OCEANVIEW
$1,154
BALCONY
$1,372
SUITE
$3,369
From (per person) 937
View Trip
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Cruise Lines Exploring The Med

Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

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